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Items: 1 to 20 of 274


The Multiple Biological Targets of Hops and Bioactive Compounds.

Bolton JL, Dunlap TL, Hajirahimkhan DA, Mbachu OC, Chen SN, Chadwick L, Nikolic D, van Breemen RB, Pauli GF, Dietz BM.

Chem Res Toxicol. 2019 Jan 4. doi: 10.1021/acs.chemrestox.8b00345. [Epub ahead of print]


Finding the bad actor: Challenges in identifying toxic constituents in botanical dietary supplements.

Roberts GK, Gardner D, Foster PM, Howard PC, Lui E, Walker L, van Breemen RB, Auerbach SS, Rider C.

Food Chem Toxicol. 2018 Dec 21;124:431-438. doi: 10.1016/j.fct.2018.12.026. [Epub ahead of print] Review.


Evidence for Chemopreventive and Resilience Activity of Licorice: Glycyrrhiza Glabra and G. Inflata Extracts Modulate Estrogen Metabolism in ACI Rats.

Wang S, Dunlap TL, Huang L, Liu Y, Simmler C, Lantvit DD, Crosby J, Howell CE, Dong H, Chen SN, Pauli GF, van Breemen RB, Dietz BM, Bolton JL.

Cancer Prev Res (Phila). 2018 Dec;11(12):819-830. doi: 10.1158/1940-6207.CAPR-18-0178. Epub 2018 Oct 4.


Rapid Determination of Procyanidins Using MALDI-ToF/ToF Mass Spectrometry.

Rush MD, Rue EA, Wong A, Kowalski P, Glinski JA, van Breemen RB.

J Agric Food Chem. 2018 Oct 31;66(43):11355-11361. doi: 10.1021/acs.jafc.8b04258. Epub 2018 Oct 16.


Analysis of lanthionine ketimine ethyl ester in mouse serum, whole blood and tissues using ultrahigh-pressure liquid chromatography/tandem mass spectrometry.

Muchiri RN, Kowal KE, Hensley K, Feinstein DL, van Breemen RB.

Rapid Commun Mass Spectrom. 2018 Nov 30;32(22):1941-1948. doi: 10.1002/rcm.8263.


Matrix-Assisted Laser Desorption/Ionization Imaging Portrays Locoregional Drug Delivery.

Gaba RC, Kowalski PJ, van Breemen RB.

J Vasc Interv Radiol. 2018 Aug;29(8):1109. doi: 10.1016/j.jvir.2017.12.003. No abstract available.


Procyanidins: a comprehensive review encompassing structure elucidation via mass spectrometry.

Rue EA, Rush MD, van Breemen RB.

Phytochem Rev. 2018 Feb;17(1):1-16. doi: 10.1007/s11101-017-9507-3. Epub 2017 May 9.


Estrogen Receptor (ER) Subtype Selectivity Identifies 8-Prenylapigenin as an ERβ Agonist from Glycyrrhiza inflata and Highlights the Importance of Chemical and Biological Authentication.

Hajirahimkhan A, Mbachu O, Simmler C, Ellis SG, Dong H, Nikolic D, Lankin DC, van Breemen RB, Chen SN, Pauli GF, Dietz BM, Bolton JL.

J Nat Prod. 2018 Apr 27;81(4):966-975. doi: 10.1021/acs.jnatprod.7b01070. Epub 2018 Apr 11.


Analysis of age-related changes in psychosine metabolism in the human brain.

Marshall MS, Jakubauskas B, Bogue W, Stoskute M, Hauck Z, Rue E, Nichols M, DiAntonio LL, van Breemen RB, Kordower JH, Saavedra-Matiz CA, Bongarzone ER.

PLoS One. 2018 Feb 26;13(2):e0193438. doi: 10.1371/journal.pone.0193438. eCollection 2018.


Long-Term Improvement of Neurological Signs and Metabolic Dysfunction in a Mouse Model of Krabbe's Disease after Global Gene Therapy.

Marshall MS, Issa Y, Jakubauskas B, Stoskute M, Elackattu V, Marshall JN, Bogue W, Nguyen D, Hauck Z, Rue E, Karumuthil-Melethil S, Zaric V, Bosland M, van Breemen RB, Givogri MI, Gray SJ, Crocker SJ, Bongarzone ER.

Mol Ther. 2018 Mar 7;26(3):874-889. doi: 10.1016/j.ymthe.2018.01.009. Epub 2018 Jan 17.


Does doxorubicin survive thermal ablation? Results of an ex vivo bench top study.

Morrison JD, Schlager CK, Lee AE, van Breemen RB, Gaba RC.

Diagn Interv Radiol. 2018 Jan-Feb;24(1):28-30. doi: 10.5152/dir.2018.17382.


Hepatic metabolism of licochalcone A, a potential chemopreventive chalcone from licorice (Glycyrrhiza inflata), determined using liquid chromatography-tandem mass spectrometry.

Huang L, Nikolic D, van Breemen RB.

Anal Bioanal Chem. 2017 Dec;409(30):6937-6948. doi: 10.1007/s00216-017-0642-x. Epub 2017 Nov 10.


Evaluation of estrogenic potency of a standardized hops extract on mammary gland biology and on MNU-induced mammary tumor growth in rats.

Keiler AM, Macejova D, Dietz BM, Bolton JL, Pauli GF, Chen SN, van Breemen RB, Nikolic D, Goerl F, Muders MH, Zierau O, Vollmer G.

J Steroid Biochem Mol Biol. 2017 Nov;174:234-241. doi: 10.1016/j.jsbmb.2017.09.020. Epub 2017 Sep 28.


A standardized Humulus lupulus (L.) ethanol extract partially prevents ovariectomy-induced bone loss in the rat without induction of adverse effects in the uterus.

Keiler AM, Helle J, Bader MI, Ehrhardt T, Nestler K, Kretzschmar G, Bernhardt R, Vollmer G, Nikolić D, Bolton JL, Pauli GF, Chen SN, Dietz BM, van Breemen RB, Zierau O.

Phytomedicine. 2017 Oct 15;34:50-58. doi: 10.1016/j.phymed.2017.08.001. Epub 2017 Aug 2.


DESIGNER Extracts as Tools to Balance Estrogenic and Chemopreventive Activities of Botanicals for Women's Health.

Dietz BM, Chen SN, Alvarenga RFR, Dong H, Nikolić D, Biendl M, van Breemen RB, Bolton JL, Pauli GF.

J Nat Prod. 2017 Aug 25;80(8):2284-2294. doi: 10.1021/acs.jnatprod.7b00284. Epub 2017 Aug 16.


Cytochrome P450 inhibition by three licorice species and fourteen licorice constituents.

Li G, Simmler C, Chen L, Nikolic D, Chen SN, Pauli GF, van Breemen RB.

Eur J Pharm Sci. 2017 Nov 15;109:182-190. doi: 10.1016/j.ejps.2017.07.034. Epub 2017 Jul 31.


Prostate Cancer Risk and DNA Methylation Signatures in Aging Rats following Developmental BPA Exposure: A Dose-Response Analysis.

Prins GS, Ye SH, Birch L, Zhang X, Cheong A, Lin H, Calderon-Gierszal E, Groen J, Hu WY, Ho SM, van Breemen RB.

Environ Health Perspect. 2017 Jul 11;125(7):077007. doi: 10.1289/EHP1050.


Isolation and structural characterization of dihydrobenzofuran congeners of licochalcone A.

Simmler C, Lankin DC, Nikolić D, van Breemen RB, Pauli GF.

Fitoterapia. 2017 Sep;121:6-15. doi: 10.1016/j.fitote.2017.06.017. Epub 2017 Jun 21.


Collision-induced dissociation of phenethylamides: role of ion-neutral complexes.

Nikolić D, Macias C, Lankin DC, van Breemen RB.

Rapid Commun Mass Spectrom. 2017 Sep 15;31(17):1385-1395. doi: 10.1002/rcm.7915.


Development of a Magnetic Microbead Affinity Selection Screen (MagMASS) Using Mass Spectrometry for Ligands to the Retinoid X Receptor-α.

Rush MD, Walker EM, Prehna G, Burton T, van Breemen RB.

J Am Soc Mass Spectrom. 2017 Mar;28(3):479-485. doi: 10.1007/s13361-016-1564-0. Epub 2016 Dec 13.

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