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Items: 13


Disease Phenotypes in a Mouse Model of RNA Toxicity Are Independent of Protein Kinase Cα and Protein Kinase Cβ.

Kim YK, Yadava RS, Mandal M, Mahadevan K, Yu Q, Leitges M, Mahadevan MS.

PLoS One. 2016 Sep 22;11(9):e0163325. doi: 10.1371/journal.pone.0163325. eCollection 2016.


TWEAK Regulates Muscle Functions in a Mouse Model of RNA Toxicity.

Yadava RS, Foff EP, Yu Q, Gladman JT, Zheng TS, Mahadevan MS.

PLoS One. 2016 Feb 22;11(2):e0150192. doi: 10.1371/journal.pone.0150192. eCollection 2016. Erratum in: PLoS One. 2018 Feb 8;13(2):e0192816.


TWEAK/Fn14, a pathway and novel therapeutic target in myotonic dystrophy.

Yadava RS, Foff EP, Yu Q, Gladman JT, Kim YK, Bhatt KS, Thornton CA, Zheng TS, Mahadevan MS.

Hum Mol Genet. 2015 Apr 1;24(7):2035-48. doi: 10.1093/hmg/ddu617. Epub 2014 Dec 11.


NKX2-5, a modifier of skeletal muscle pathology due to RNA toxicity.

Gladman JT, Yadava RS, Mandal M, Yu Q, Kim YK, Mahadevan MS.

Hum Mol Genet. 2015 Jan 1;24(1):251-64. doi: 10.1093/hmg/ddu443. Epub 2014 Aug 28.


Evaluating the effects of CELF1 deficiency in a mouse model of RNA toxicity.

Kim YK, Mandal M, Yadava RS, Paillard L, Mahadevan MS.

Hum Mol Genet. 2014 Jan 15;23(2):293-302. doi: 10.1093/hmg/ddt419. Epub 2013 Sep 2.


The RNA-binding protein Staufen1 is increased in DM1 skeletal muscle and promotes alternative pre-mRNA splicing.

Ravel-Chapuis A, Bélanger G, Yadava RS, Mahadevan MS, DesGroseillers L, Côté J, Jasmin BJ.

J Cell Biol. 2012 Mar 19;196(6):699-712. doi: 10.1083/jcb.201108113.


RNA toxicity in myotonic muscular dystrophy induces NKX2-5 expression.

Yadava RS, Frenzel-McCardell CD, Yu Q, Srinivasan V, Tucker AL, Puymirat J, Thornton CA, Prall OW, Harvey RP, Mahadevan MS.

Nat Genet. 2008 Jan;40(1):61-8. Epub 2007 Dec 16.


Reversible model of RNA toxicity and cardiac conduction defects in myotonic dystrophy.

Mahadevan MS, Yadava RS, Yu Q, Balijepalli S, Frenzel-McCardell CD, Bourne TD, Phillips LH.

Nat Genet. 2006 Sep;38(9):1066-70. Epub 2006 Jul 30.


Expression of lexA targeted ribozyme in Escherichia coli BL-21 (DE3) cells.

Yadava RS, Kumar R, Yadava PK.

Mol Cell Biochem. 2005 Mar;271(1-2):197-203.


Kinetic analysis of ribozyme-substrate complex formation in yeast.

Yadava RS, Mahen EM, Fedor MJ.

RNA. 2004 May;10(5):863-79.


Hairpin ribozymes with four-way helical junctions mediate intracellular RNA ligation.

Yadava RS, Choi AJ, Lebruska LL, Fedor MJ.

J Mol Biol. 2001 Jun 15;309(4):893-902.


The kinetic mechanism of the hairpin ribozyme in vivo: influence of RNA helix stability on intracellular cleavage kinetics.

Donahue CP, Yadava RS, Nesbitt SM, Fedor MJ.

J Mol Biol. 2000 Jan 21;295(3):693-707.


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