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Machine intelligence decrypts β-lapachone as an allosteric 5-lipoxygenase inhibitor.

Rodrigues T, Werner M, Roth J, da Cruz EHG, Marques MC, Akkapeddi P, Lobo SA, Koeberle A, Corzana F, da Silva Júnior EN, Werz O, Bernardes GJL.

Chem Sci. 2018 Jul 17;9(34):6899-6903. doi: 10.1039/c8sc02634c. eCollection 2018 Sep 14.


[How many patients had their colon investigated within five years prior to colorectal cancer diagnosis?]

Falk H, Olsson H, Werner M, Karling P.

Lakartidningen. 2018 Oct 2;115. pii: E9YX. Swedish.


Pillars of Life: Is There a Relationship between Lifestyle Factors and the Surface Characteristics of Dragonfly Wings?

Cheeseman S, Owen S, Truong VK, Meyer D, Ng SH, Vongsvivut J, Linklater D, Tobin MJ, Werner M, Baulin VA, Luque P, Marchant R, Juodkazis S, Crawford RJ, Ivanova EP.

ACS Omega. 2018 Jun 30;3(6):6039-6046. doi: 10.1021/acsomega.8b00776. Epub 2018 Jun 5.


Large-Deviation Properties of Sequence Alignment of Correlated Sequences.

Werner M, Fieth P, Hartmann A.

J Comput Biol. 2018 Sep 10. doi: 10.1089/cmb.2017.0269. [Epub ahead of print]


Proteome Profiling of Primary Pancreatic Ductal Adenocarcinomas Undergoing Additive Chemoradiation Link ALDH1A1 to Early Local Recurrence and Chemoradiation Resistance.

Oria VO, Bronsert P, Thomsen AR, Föll MC, Zamboglou C, Hannibal L, Behringer S, Biniossek ML, Schreiber C, Grosu AL, Bolm L, Rades D, Keck T, Werner M, Wellner UF, Schilling O.

Transl Oncol. 2018 Dec;11(6):1307-1322. doi: 10.1016/j.tranon.2018.08.001. Epub 2018 Aug 30.


A Five-MicroRNA Signature Predicts Survival and Disease Control of Patients with Head and Neck Cancer Negative for HPV-infection.

Hess J, Unger K, Maihoefer C, Schüttrumpf L, Wintergerst L, Heider T, Weber P, Marschner S, Braselmann H, Samaga D, Kuger S, Pflugradt U, Baumeister P, Walch A, Woischke C, Kirchner T, Werner M, Werner K, Baumann M, Budach V, Combs SE, Debus J, Grosu AL, Krause M, Linge A, Rödel C, Stuschke M, Zips D, Zitzelsberger HF, Ganswindt U, Henke M, Belka C.

Clin Cancer Res. 2018 Aug 31. pii: clincanres.0776.2018. doi: 10.1158/1078-0432.CCR-18-0776. [Epub ahead of print]


Reconciling glacial Antarctic water stable isotopes with ice sheet topography and the isotopic paleothermometer.

Werner M, Jouzel J, Masson-Delmotte V, Lohmann G.

Nat Commun. 2018 Aug 30;9(1):3537. doi: 10.1038/s41467-018-05430-y.


Evaluation of FSH, LH, testosterone levels and semen parameters in male boron workers under extreme exposure conditions.

Duydu Y, Başaran N, Aydın S, Üstündağ A, Yalçın CÖ, Anlar HG, Bacanlı M, Aydos K, Atabekoğlu CS, Golka K, Ickstadt K, Schwerdtle T, Werner M, Meyer S, Bolt HM.

Arch Toxicol. 2018 Oct;92(10):3051-3059. doi: 10.1007/s00204-018-2296-7. Epub 2018 Aug 25.


[Osteomalacia-Clinical aspects, diagnostics and treatment].

Tiefenbach M, Scheel M, Maier A, Gehlen M, Schwarz-Eywill M, Werner M, Siebers-Renelt U, Hammer M.

Z Rheumatol. 2018 Oct;77(8):703-718. doi: 10.1007/s00393-018-0510-x. German.


Mesoscale substrate curvature overrules nanoscale contact guidance to direct bone marrow stromal cell migration.

Werner M, Kurniawan NA, Korus G, Bouten CVC, Petersen A.

J R Soc Interface. 2018 Aug;15(145). pii: 20180162. doi: 10.1098/rsif.2018.0162.


Proteomic distinction of renal oncocytomas and chromophobe renal cell carcinomas.

Drendel V, Heckelmann B, Schell C, Kook L, Biniossek ML, Werner M, Jilg CA, Schilling O.

Clin Proteomics. 2018 Aug 3;15:25. doi: 10.1186/s12014-018-9200-6. eCollection 2018.


Peri-arterial Autonomic Innervation of the Human Ear.

Cakmak YO, Cotofana S, Jäger C, Morawski M, Sora MC, Werner M, Hammer N.

Sci Rep. 2018 Jul 31;8(1):11469. doi: 10.1038/s41598-018-29839-z.


Utilization of 3D printing technology to facilitate and standardize soft tissue testing.

Scholze M, Singh A, Lozano PF, Ondruschka B, Ramezani M, Werner M, Hammer N.

Sci Rep. 2018 Jul 27;8(1):11340. doi: 10.1038/s41598-018-29583-4.


Discovery of a benzenesulfonamide-based dual inhibitor of microsomal prostaglandin E2 synthase-1 and 5-lipoxygenase that favorably modulates lipid mediator biosynthesis in inflammation.

Cheung SY, Werner M, Esposito L, Troisi F, Cantone V, Liening S, König S, Gerstmeier J, Koeberle A, Bilancia R, Rizza R, Rossi A, Roviezzo F, Temml V, Schuster D, Stuppner H, Schubert-Zsilavecz M, Werz O, Hanke T, Pace S.

Eur J Med Chem. 2018 Aug 5;156:815-830. doi: 10.1016/j.ejmech.2018.07.031. Epub 2018 Jul 25.


North Pacific freshwater events linked to changes in glacial ocean circulation.

Maier E, Zhang X, Abelmann A, Gersonde R, Mulitza S, Werner M, Méheust M, Ren J, Chapligin B, Meyer H, Stein R, Tiedemann R, Lohmann G.

Nature. 2018 Jul;559(7713):241-245. doi: 10.1038/s41586-018-0276-y. Epub 2018 Jul 11.


Bridging molecular simulation models and elastic theories for amphiphilic membranes.

Berthault A, Werner M, Baulin VA.

J Chem Phys. 2018 Jul 7;149(1):014902. doi: 10.1063/1.5027895.


CC-Chemokine Ligand 18 Is an Independent Prognostic Marker in Lymph Node-positive Non-small Cell Lung Cancer.

Schmid S, Csanadi A, Kozhuharov N, Tchudjin M, Kayser C, Rawluk J, Passlick B, Werner M, Prasse A, Kayser G.

Anticancer Res. 2018 Jul;38(7):3913-3918. doi: 10.21873/anticanres.12676.


Scale-up of the ex vivo expansion of encapsulated primary human T lymphocytes.

Kaiser P, Werner M, Jérôme V, Freitag R.

Biotechnol Bioeng. 2018 Oct;115(10):2632-2642. doi: 10.1002/bit.26786. Epub 2018 Jul 16.


Birth weights of newborns and pregnancy outcomes of environmentally boron-exposed females in Turkey.

Duydu Y, Başaran N, Üstündağ A, Aydın S, Yalçın CÖ, Anlar HG, Bacanlı M, Aydos K, Atabekoğlu CS, Golka K, Ickstadt K, Schwerdtle T, Werner M, Meyer S, Bolt HM.

Arch Toxicol. 2018 Aug;92(8):2475-2485. doi: 10.1007/s00204-018-2238-4. Epub 2018 Jun 8.


High-Grade Osteosarcoma of the Foot: Presentation, Treatment, Prognostic Factors, and Outcome of 23 Cooperative Osteosarcoma Study Group COSS Patients.

Schuster AJ, Kager L, Reichardt P, Baumhoer D, Csóka M, Hecker-Nolting S, Lang S, Lorenzen S, Mayer-Steinacker R, von Kalle T, Kevric M, Werner M, Windhager R, Wirth T, Bielack SS.

Sarcoma. 2018 May 2;2018:1632978. doi: 10.1155/2018/1632978. eCollection 2018.

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