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Items: 19


Association of soluble TREM-like transcript-1 with clinical features and patient reported outcomes in systemic lupus erythematosus.

Vázquez-Otero I, Rodríguez-Navedo Y, Vilá-Rivera K, Nieves-Plaza M, Morales-Ortiz J, Washington AV, Vilá LM.

Eur J Rheumatol. 2018 Oct 10:1-5. doi: 10.5152/eurjrheum.2018.18074. [Epub ahead of print]


TLT-1 is a Prognostic Indicator in ALI/ARDS and Prevents Tissue Damage in the Lungs in a Mouse model.

Morales-Ortíz J, Deal V, Reyes F, Maldonado-Martínez G, Ledesma N, Staback F, Croft C, Pacheco A, Ortiz-Zuazaga H, Yost CC, Rowley JW, Madera B, St John A, Chen J, Lopez J, Rondina MT, Hunter R, Gibson A, Washington AV.

Blood. 2018 Oct 3. pii: blood-2018-03-841593. doi: 10.1182/blood-2018-03-841593. [Epub ahead of print]


Amyloid Beta Peptide Is Released during Thrombosis in the Skin.

Kucheryavykh LY, Kucheryavykh YV, Washington AV, Inyushin MY.

Int J Mol Sci. 2018 Jun 8;19(6). pii: E1705. doi: 10.3390/ijms19061705.


High Levels of Soluble Triggering Receptor Expressed on Myeloid Cells-Like Transcript (TLT)-1 Are Associated With Acute Respiratory Distress Syndrome.

Morales-Ortíz J, Rondina MT, Brown SM, Grissom C, Washington AV.

Clin Appl Thromb Hemost. 2018 Oct;24(7):1122-1127. doi: 10.1177/1076029618774149. Epub 2018 May 14.


The Characterization of Monoclonal Antibodies to Mouse TLT-1 Suggests That TLT-1 Plays a Role in Wound Healing.

Manfredi B, Morales-Ortíz J, Díaz-Díaz LM, Hernandez-Matias L, Barreto-Vázquez D, Menéndez-Pérez J, Rodríguez-Cordero JA, Villalobos-Santos JC, Santiago-Rivera E, Rivera-Dompenciel A, Lozada-Delgado EL, Kuchibhotla M, Carrasquillo-Carrión K, Roche-Lima A, Washington AV.

Monoclon Antib Immunodiagn Immunother. 2018 Apr;37(2):78-86. doi: 10.1089/mab.2017.0063.


Platelets are responsible for the accumulation of β-amyloid in blood clots inside and around blood vessels in mouse brain after thrombosis.

Kucheryavykh LY, Dávila-Rodríguez J, Rivera-Aponte DE, Zueva LV, Washington AV, Sanabria P, Inyushin MY.

Brain Res Bull. 2017 Jan;128:98-105. doi: 10.1016/j.brainresbull.2016.11.008. Epub 2016 Nov 28.


The Rac Inhibitor EHop-016 Inhibits Mammary Tumor Growth and Metastasis in a Nude Mouse Model.

Castillo-Pichardo L, Humphries-Bickley T, De La Parra C, Forestier-Roman I, Martinez-Ferrer M, Hernandez E, Vlaar C, Ferrer-Acosta Y, Washington AV, Cubano LA, Rodriguez-Orengo J, Dharmawardhane S.

Transl Oncol. 2014 Oct 24;7(5):546-55. doi: 10.1016/j.tranon.2014.07.004. eCollection 2014 Oct.


Levels of soluble TREM-like transcript 1 in patients presenting to the emergency department with chest pain.

Esponda OL, Hunter R, Del Río JR, Washington AV.

Clin Appl Thromb Hemost. 2015 Jan;21(1):30-4. doi: 10.1177/1076029614547298. Epub 2014 Aug 21.


The addition of a pregnenolone pendant group enhances the anticancer properties of titanocene dichloride in a mcf-7 xenograft model.

Ramos G, Loperena Y, Ortiz G, Reyes F, Szeto A, Vera J, Velez J, Morales J, Morrero D, Castillo L, Dharmawardhane S, Melendez E, Washington AV.

Anticancer Res. 2014 Apr;34(4):1609-15.


Clinical studies support a role for trem-like transcript-1 during the progression of sepsis.

Esponda O, Morales J, Aguilar A, Gomez M, Washington AV.

Bol Asoc Med P R. 2010 Jul-Sep;102(3):59-61. Review.


Soluble TLT-1 modulates platelet-endothelial cell interactions and actin polymerization.

Morales J, Villa K, Gattis J, Castro W, Colon K, Lubkowski J, Sanabria P, Hunter R, Washington AV.

Blood Coagul Fibrinolysis. 2010 Apr;21(3):229-36. doi: 10.1097/MBC.0b013e3283358116.


Visualization and identification of IL-7 producing cells in reporter mice.

Mazzucchelli RI, Warming S, Lawrence SM, Ishii M, Abshari M, Washington AV, Feigenbaum L, Warner AC, Sims DJ, Li WQ, Hixon JA, Gray DH, Rich BE, Morrow M, Anver MR, Cherry J, Naf D, Sternberg LR, McVicar DW, Farr AG, Germain RN, Rogers K, Jenkins NA, Copeland NG, Durum SK.

PLoS One. 2009 Nov 10;4(11):e7637. doi: 10.1371/journal.pone.0007637.


TREM-like transcript-1 protects against inflammation-associated hemorrhage by facilitating platelet aggregation in mice and humans.

Washington AV, Gibot S, Acevedo I, Gattis J, Quigley L, Feltz R, De La Mota A, Schubert RL, Gomez-Rodriguez J, Cheng J, Dutra A, Pak E, Chertov O, Rivera L, Morales J, Lubkowski J, Hunter R, Schwartzberg PL, McVicar DW.

J Clin Invest. 2009 Jun;119(6):1489-501. doi: 10.1172/JCI36175. Epub 2009 May 11.


Phenotypic heterogeneity in the Gray platelet syndrome extends to the expression of TREM family member, TLT-1.

Nurden AT, Nurden P, Bermejo E, Combrié R, McVicar DW, Washington AV.

Thromb Haemost. 2008 Jul;100(1):45-51. doi: 10.1160/TH08-02-0067.


Combined resveratrol, quercetin, and catechin treatment reduces breast tumor growth in a nude mouse model.

Schlachterman A, Valle F, Wall KM, Azios NG, Castillo L, Morell L, Washington AV, Cubano LA, Dharmawardhane SF.

Transl Oncol. 2008 Mar;1(1):19-27.


Receptors involved in the regulation of murine NK cells.

Washington AV, McVicar DW.

Curr Protoc Immunol. 2004 May;Appendix 1:Appendix 1R. doi: 10.1002/0471142735.ima01rs59.


The structure of the extracellular domain of triggering receptor expressed on myeloid cells like transcript-1 and evidence for a naturally occurring soluble fragment.

Gattis JL, Washington AV, Chisholm MM, Quigley L, Szyk A, McVicar DW, Lubkowski J.

J Biol Chem. 2006 May 12;281(19):13396-403. Epub 2006 Feb 27.


A TREM family member, TLT-1, is found exclusively in the alpha-granules of megakaryocytes and platelets.

Washington AV, Schubert RL, Quigley L, Disipio T, Feltz R, Cho EH, McVicar DW.

Blood. 2004 Aug 15;104(4):1042-7. Epub 2004 Apr 20.


Initial characterization of TREM-like transcript (TLT)-1: a putative inhibitory receptor within the TREM cluster.

Washington AV, Quigley L, McVicar DW.

Blood. 2002 Nov 15;100(10):3822-4. Epub 2002 Jul 12.

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