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Supplementation with dairy matrices impacts on homocysteine levels and gut microbiota composition of hyperhomocysteinemic mice.

Zinno P, Motta V, Guantario B, Natella F, Roselli M, Bello C, Comitato R, Carminati D, Tidona F, Meucci A, Aiello P, Perozzi G, Virgili F, Trevisi P, Canali R, Devirgiliis C.

Eur J Nutr. 2019 Jan 30. doi: 10.1007/s00394-019-01911-y. [Epub ahead of print]


Protective Effect of Proanthocyanidins in a Rat Model of Mild Intestinal Inflammation and Impaired Intestinal Permeability Induced by LPS.

Gil-Cardoso K, Comitato R, Ginés I, Ardévol A, Pinent M, Virgili F, Terra X, Blay M.

Mol Nutr Food Res. 2019 Apr;63(8):e1800720. doi: 10.1002/mnfr.201800720. Epub 2019 Jan 23.


Genetic Polymorphisms and Zinc Status: Implications for Supplementation in Metabolic Diseases.

Virgili F, Ambra R, McCormack J, Simpson EEA, Ciarapica D, Barnaba L, Azzini E, Polito A.

Curr Pharm Des. 2018;24(35):4131-4143. doi: 10.2174/1381612824666181016155903.


Alpha-lipoic acid, but not di-hydrolipoic acid, activates Nrf2 response in primary human umbilical-vein endothelial cells and protects against TNF-α induced endothelium dysfunction.

Fratantonio D, Speciale A, Molonia MS, Bashllari R, Palumbo M, Saija A, Cimino F, Monastra G, Virgili F.

Arch Biochem Biophys. 2018 Oct 1;655:18-25. doi: 10.1016/ Epub 2018 Aug 8.


OxInflammation: From Subclinical Condition to Pathological Biomarker.

Valacchi G, Virgili F, Cervellati C, Pecorelli A.

Front Physiol. 2018 Jul 9;9:858. doi: 10.3389/fphys.2018.00858. eCollection 2018. Review.


Need (more than) two to Tango: Multiple tools to adapt to changes in oxygen availability.

Fratantonio D, Cimino F, Speciale A, Virgili F.

Biofactors. 2018 May;44(3):207-218. doi: 10.1002/biof.1419. Epub 2018 Feb 27. Review.


Proposed guidelines to evaluate scientific validity and evidence for genotype-based dietary advice.

Grimaldi KA, van Ommen B, Ordovas JM, Parnell LD, Mathers JC, Bendik I, Brennan L, Celis-Morales C, Cirillo E, Daniel H, de Kok B, El-Sohemy A, Fairweather-Tait SJ, Fallaize R, Fenech M, Ferguson LR, Gibney ER, Gibney M, Gjelstad IMF, Kaput J, Karlsen AS, Kolossa S, Lovegrove J, Macready AL, Marsaux CFM, Alfredo Martinez J, Milagro F, Navas-Carretero S, Roche HM, Saris WHM, Traczyk I, van Kranen H, Verschuren L, Virgili F, Weber P, Bouwman J.

Genes Nutr. 2017 Dec 15;12:35. doi: 10.1186/s12263-017-0584-0. eCollection 2017. Review.


Tocotrienols: A Family of Molecules with Specific Biological Activities.

Comitato R, Ambra R, Virgili F.

Antioxidants (Basel). 2017 Nov 18;6(4). pii: E93. doi: 10.3390/antiox6040093. Review.


Propelling the paradigm shift from reductionism to systems nutrition.

Kaput J, Perozzi G, Radonjic M, Virgili F.

Genes Nutr. 2017 Jan 25;12:3. doi: 10.1186/s12263-016-0549-8. eCollection 2017.


Tocotrienols induce endoplasmic reticulum stress and apoptosis in cervical cancer cells.

Comitato R, Guantario B, Leoni G, Nesaretnam K, Ronci MB, Canali R, Virgili F.

Genes Nutr. 2016 Dec 23;11:32. doi: 10.1186/s12263-016-0543-1. eCollection 2016.


Cyanidin-3-O-glucoside ameliorates palmitate-induced insulin resistance by modulating IRS-1 phosphorylation and release of endothelial derived vasoactive factors.

Fratantonio D, Cimino F, Molonia MS, Ferrari D, Saija A, Virgili F, Speciale A.

Biochim Biophys Acta Mol Cell Biol Lipids. 2017 Mar;1862(3):351-357. doi: 10.1016/j.bbalip.2016.12.008. Epub 2016 Dec 21.


Low nanomolar caffeic acid attenuates high glucose-induced endothelial dysfunction in primary human umbilical-vein endothelial cells by affecting NF-κB and Nrf2 pathways.

Fratantonio D, Speciale A, Canali R, Natarelli L, Ferrari D, Saija A, Virgili F, Cimino F.

Biofactors. 2017 Jan 2;43(1):54-62. doi: 10.1002/biof.1312. Epub 2016 Jul 13.


A red orange extract modulates the vascular response to a recreational dive: a pilot study on the effect of anthocyanins on the physiological consequences of scuba diving.

Balestra C, Cimino F, Theunissen S, Snoeck T, Provyn S, Canali R, Bonina A, Virgili F.

Nat Prod Res. 2016 Sep;30(18):2101-6. doi: 10.1080/14786419.2015.1107062. Epub 2015 Nov 7.


Nanomolar Caffeic Acid Decreases Glucose Uptake and the Effects of High Glucose in Endothelial Cells.

Natarelli L, Ranaldi G, Leoni G, Roselli M, Guantario B, Comitato R, Ambra R, Cimino F, Speciale A, Virgili F, Canali R.

PLoS One. 2015 Nov 6;10(11):e0142421. doi: 10.1371/journal.pone.0142421. eCollection 2015.


Human nutrition, environment, and health.

Kaput J, Kussmann M, Radonjic M, Virgili F, Perozzi G.

Genes Nutr. 2015 Sep;10(5):489. doi: 10.1007/s12263-015-0489-8. No abstract available.


Sex hormones and macronutrient metabolism.

Comitato R, Saba A, Turrini A, Arganini C, Virgili F.

Crit Rev Food Sci Nutr. 2015;55(2):227-41. doi: 10.1080/10408398.2011.651177. Review.


Bioavailability and molecular activities of anthocyanins as modulators of endothelial function.

Speciale A, Cimino F, Saija A, Canali R, Virgili F.

Genes Nutr. 2014 Jul;9(4):404. doi: 10.1007/s12263-014-0404-8. Epub 2014 May 17.


Transcriptome analysis of human primary endothelial cells (HUVEC) from umbilical cords of gestational diabetic mothers reveals candidate sites for an epigenetic modulation of specific gene expression.

Ambra R, Manca S, Palumbo MC, Leoni G, Natarelli L, De Marco A, Consoli A, Pandolfi A, Virgili F.

Genomics. 2014 May-Jun;103(5-6):337-48. doi: 10.1016/j.ygeno.2014.03.003. Epub 2014 Mar 22.


Vitamin C supplementation modulates gene expression in peripheral blood mononuclear cells specifically upon an inflammatory stimulus: a pilot study in healthy subjects.

Canali R, Natarelli L, Leoni G, Azzini E, Comitato R, Sancak O, Barella L, Virgili F.

Genes Nutr. 2014 May;9(3):390. doi: 10.1007/s12263-014-0390-x. Epub 2014 Mar 7.


Cyanidin-3-O-glucoside modulates intracellular redox status and prevents HIF-1 stabilization in endothelial cells in vitro exposed to chronic hypoxia.

Anwar S, Speciale A, Fratantonio D, Cristani M, Saija A, Virgili F, Cimino F.

Toxicol Lett. 2014 Apr 21;226(2):206-13. doi: 10.1016/j.toxlet.2014.01.048. Epub 2014 Feb 8.


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