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Items: 1 to 20 of 231

1.

Oxidative stress-induced senescence markedly increases disc cell bioenergetics.

Patil P, Falabella M, Saeed A, Lee D, Kaufman B, Shiva S, Croix CS, Van Houten B, Neidernhofer LJ, Robbins PD, Lee J, Gwendolyn S, Vo N.

Mech Ageing Dev. 2019 Apr 16. pii: S0047-6374(18)30198-2. doi: 10.1016/j.mad.2019.04.006. [Epub ahead of print]

PMID:
31002926
2.

Guidelines for DNA recombination and repair studies: Mechanistic assays of DNA repair processes.

Klein HL, Ang KKH, Arkin MR, Beckwitt EC, Chang YH, Fan J, Kwon Y, Morten MJ, Mukherjee S, Pambos OJ, El Sayyed H, Thrall ES, Vieira-da-Rocha JP, Wang Q, Wang S, Yeh HY, Biteen JS, Chi P, Heyer WD, Kapanidis AN, Loparo JJ, Strick TR, Sung P, Van Houten B, Niu H, Rothenberg E.

Microb Cell. 2019 Jan 7;6(1):65-101. doi: 10.15698/mic2019.01.665. Review.

3.

Age-related declines in α-Klotho drive progenitor cell mitochondrial dysfunction and impaired muscle regeneration.

Sahu A, Mamiya H, Shinde SN, Cheikhi A, Winter LL, Vo NV, Stolz D, Roginskaya V, Tang WY, St Croix C, Sanders LH, Franti M, Van Houten B, Rando TA, Barchowsky A, Ambrosio F.

Nat Commun. 2018 Nov 19;9(1):4859. doi: 10.1038/s41467-018-07253-3.

4.

Mitochondrial energetics is impaired in very long-chain acyl-CoA dehydrogenase deficiency and can be rescued by treatment with mitochondria-targeted electron scavengers.

Seminotti B, Leipnitz G, Karunanidhi A, Kochersperger C, Roginskaya VY, Basu S, Wang Y, Wipf P, Van Houten B, Mohsen AW, Vockley J.

Hum Mol Genet. 2018 Nov 16. doi: 10.1093/hmg/ddy403. [Epub ahead of print]

5.

Age-dependent changes in intervertebral disc cell mitochondria and bioenergetics.

Hartman R, Patil P, Tisherman R, St Croix C, Niedernhofer LJ, Robbins PD, Ambrosio F, Van Houten B, Sowa G, Vo N.

Eur Cell Mater. 2018 Oct 18;36:171-183. doi: 10.22203/eCM.v036a13.

6.

Key regulators of lipid metabolism drive endocrine resistance in invasive lobular breast cancer.

Du T, Sikora MJ, Levine KM, Tasdemir N, Riggins RB, Wendell SG, Van Houten B, Oesterreich S.

Breast Cancer Res. 2018 Sep 4;20(1):106. doi: 10.1186/s13058-018-1041-8.

7.

Single-cell mutagenic responses and cell death revealed in real time.

Van Houten B, Kad NM.

Proc Natl Acad Sci U S A. 2018 Jul 10;115(28):7168-7170. doi: 10.1073/pnas.1808986115. Epub 2018 Jun 26. No abstract available.

8.

Cancer-Associated Fibroblasts Drive Glycolysis in a Targetable Signaling Loop Implicated in Head and Neck Squamous Cell Carcinoma Progression.

Kumar D, New J, Vishwakarma V, Joshi R, Enders J, Lin F, Dasari S, Gutierrez WR, Leef G, Ponnurangam S, Chavan H, Ganaden L, Thornton MM, Dai H, Tawfik O, Straub J, Shnayder Y, Kakarala K, Tsue TT, Girod DA, Van Houten B, Anant S, Krishnamurthy P, Thomas SM.

Cancer Res. 2018 Jul 15;78(14):3769-3782. doi: 10.1158/0008-5472.CAN-17-1076. Epub 2018 May 16.

PMID:
29769197
9.

[Trimethylaminuria: 'Help, my child smells of fish!']

Stehmann TA, van Houten B, van der Deure J.

Ned Tijdschr Geneeskd. 2018;162:D2068. Dutch.

PMID:
29600922
10.

Combination of a thioxodihydroquinazolinone with cisplatin eliminates ovarian cancer stem cell-like cells (CSC-LCs) and shows preclinical potential.

Ma J, Salamoun J, Wipf P, Edwards R, Van Houten B, Qian W.

Oncotarget. 2017 Dec 26;9(5):6042-6054. doi: 10.18632/oncotarget.23679. eCollection 2018 Jan 19.

11.

Evaluation of mitochondrial bioenergetics, dynamics, endoplasmic reticulum-mitochondria crosstalk, and reactive oxygen species in fibroblasts from patients with complex I deficiency.

Leipnitz G, Mohsen AW, Karunanidhi A, Seminotti B, Roginskaya VY, Markantone DM, Grings M, Mihalik SJ, Wipf P, Van Houten B, Vockley J.

Sci Rep. 2018 Jan 18;8(1):1165. doi: 10.1038/s41598-018-19543-3.

12.

Recruitment of UvrBC complexes to UV-induced damage in the absence of UvrA increases cell survival.

Springall L, Hughes CD, Simons M, Azinas S, Van Houten B, Kad NM.

Nucleic Acids Res. 2018 Feb 16;46(3):1256-1265. doi: 10.1093/nar/gkx1244.

13.

DNA repair after oxidative stress: current challenges.

Van Houten B, Santa-Gonzalez GA, Camargo M.

Curr Opin Toxicol. 2018 Feb;7:9-16. doi: 10.1016/j.cotox.2017.10.009. Epub 2017 Oct 16.

14.

POLB: A new role of DNA polymerase beta in mitochondrial base excision repair.

Kaufman BA, Van Houten B.

DNA Repair (Amst). 2017 Dec;60:A1-A5. doi: 10.1016/j.dnarep.2017.11.002. Epub 2017 Nov 6. Review.

15.

PARP1 changes from three-dimensional DNA damage searching to one-dimensional diffusion after auto-PARylation or in the presence of APE1.

Liu L, Kong M, Gassman NR, Freudenthal BD, Prasad R, Zhen S, Watkins SC, Wilson SH, Van Houten B.

Nucleic Acids Res. 2017 Dec 15;45(22):12834-12847. doi: 10.1093/nar/gkx1047.

16.

Molecular cartography of mutational landscapes in melanomas.

Beckwitt EC, Van Houten B.

EMBO J. 2017 Oct 2;36(19):2812-2814. doi: 10.15252/embj.201797944. Epub 2017 Sep 20. No abstract available.

17.

Studying protein-DNA interactions using atomic force microscopy.

Beckwitt EC, Kong M, Van Houten B.

Semin Cell Dev Biol. 2018 Jan;73:220-230. doi: 10.1016/j.semcdb.2017.06.028. Epub 2017 Jun 30. Review.

18.

Single-Molecule Methods for Nucleotide Excision Repair: Building a System to Watch Repair in Real Time.

Kong M, Beckwitt EC, Springall L, Kad NM, Van Houten B.

Methods Enzymol. 2017;592:213-257. doi: 10.1016/bs.mie.2017.03.027. Epub 2017 May 31.

19.

Optical Control of DNA Helicase Function through Genetic Code Expansion.

Luo J, Kong M, Liu L, Samanta S, Van Houten B, Deiters A.

Chembiochem. 2017 Mar 2;18(5):466-469. doi: 10.1002/cbic.201600624. Epub 2017 Jan 25.

20.

Rad4 recognition-at-a-distance: Physical basis of conformation-specific anomalous diffusion of DNA repair proteins.

Kong M, Van Houten B.

Prog Biophys Mol Biol. 2017 Aug;127:93-104. doi: 10.1016/j.pbiomolbio.2016.12.004. Epub 2016 Dec 8. Review.

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