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Items: 14


An Anti-β-Amyloid Vaccine for Treating Cognitive Deficits in a Mouse Model of Down Syndrome.

Belichenko PV, Madani R, Rey-Bellet L, Pihlgren M, Becker A, Plassard A, Vuillermot S, Giriens V, Nosheny RL, Kleschevnikov AM, Valletta JS, Bengtsson SK, Linke GR, Maloney MT, Hickman DT, Reis P, Granet A, Mlaki D, Lopez-Deber MP, Do L, Singhal N, Masliah E, Pearn ML, Pfeifer A, Muhs A, Mobley WC.

PLoS One. 2016 Mar 29;11(3):e0152471. doi: 10.1371/journal.pone.0152471. eCollection 2016.


Sleep and EEG features in genetic models of Down syndrome.

Colas D, Valletta JS, Takimoto-Kimura R, Nishino S, Fujiki N, Mobley WC, Mignot E.

Neurobiol Dis. 2008 Apr;30(1):1-7. doi: 10.1016/j.nbd.2007.07.014. Epub 2007 Jul 21.


A functional dynein-microtubule network is required for NGF signaling through the Rap1/MAPK pathway.

Wu C, Ramirez A, Cui B, Ding J, Delcroix JD, Valletta JS, Liu JJ, Yang Y, Chu S, Mobley WC.

Traffic. 2007 Nov;8(11):1503-20. Epub 2007 Sep 6.


Increased App expression in a mouse model of Down's syndrome disrupts NGF transport and causes cholinergic neuron degeneration.

Salehi A, Delcroix JD, Belichenko PV, Zhan K, Wu C, Valletta JS, Takimoto-Kimura R, Kleschevnikov AM, Sambamurti K, Chung PP, Xia W, Villar A, Campbell WA, Kulnane LS, Nixon RA, Lamb BT, Epstein CJ, Stokin GB, Goldstein LS, Mobley WC.

Neuron. 2006 Jul 6;51(1):29-42.


NGF signaling in sensory neurons: evidence that early endosomes carry NGF retrograde signals.

Delcroix JD, Valletta JS, Wu C, Hunt SJ, Kowal AS, Mobley WC.

Neuron. 2003 Jul 3;39(1):69-84.


The extracellular domain of p75NTR is necessary to inhibit neurotrophin-3 signaling through TrkA.

Mischel PS, Smith SG, Vining ER, Valletta JS, Mobley WC, Reichardt LF.

J Biol Chem. 2001 Apr 6;276(14):11294-301. Epub 2001 Jan 9.


Absence of p75NTR causes increased basal forebrain cholinergic neuron size, choline acetyltransferase activity, and target innervation.

Yeo TT, Chua-Couzens J, Butcher LL, Bredesen DE, Cooper JD, Valletta JS, Mobley WC, Longo FM.

J Neurosci. 1997 Oct 15;17(20):7594-605.


Endocytosis of activated TrkA: evidence that nerve growth factor induces formation of signaling endosomes.

Grimes ML, Zhou J, Beattie EC, Yuen EC, Hall DE, Valletta JS, Topp KS, LaVail JH, Bunnett NW, Mobley WC.

J Neurosci. 1996 Dec 15;16(24):7950-64.


A comprehensive study of the spatiotemporal pattern of beta-amyloid precursor protein mRNA and protein in the rat brain: lack of modulation by exogenously applied nerve growth factor.

Neve RL, Valletta JS, Li Y, Ventosa-Michelman M, Holtzman DM, Mobley WC.

Brain Res Mol Brain Res. 1996 Jul;39(1-2):185-97.


Multiple levels for regulation of TrkA in PC12 cells by nerve growth factor.

Zhou J, Valletta JS, Grimes ML, Mobley WC.

J Neurochem. 1995 Sep;65(3):1146-56.


p140trk mRNA marks NGF-responsive forebrain neurons: evidence that trk gene expression is induced by NGF.

Holtzman DM, Li Y, Parada LF, Kinsman S, Chen CK, Valletta JS, Zhou J, Long JB, Mobley WC.

Neuron. 1992 Sep;9(3):465-78.


Nerve growth factor induces gene expression of the prion protein and beta-amyloid protein precursor in the developing hamster central nervous system.

McKinley MP, Longo FM, Valletta JS, Rahbar F, Neve RL, Prusiner SB, Mobley WC.

Prog Brain Res. 1990;86:227-38. No abstract available.


Developmental regulation of nerve growth factor and its receptor in the rat caudate-putamen.

Mobley WC, Woo JE, Edwards RH, Riopelle RJ, Longo FM, Weskamp G, Otten U, Valletta JS, Johnston MV.

Neuron. 1989 Nov;3(5):655-64.


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