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Items: 1 to 20 of 219

1.

Four principles to make evidence synthesis more useful for policy.

Donnelly CA, Boyd I, Campbell P, Craig C, Vallance P, Walport M, Whitty CJM, Woods E, Wormald C.

Nature. 2018 Jun;558(7710):361-364. doi: 10.1038/d41586-018-05414-4. No abstract available.

PMID:
29925978
2.

Industry-Academic Relationship in a New Era of Drug Discovery.

Vallance P.

J Clin Oncol. 2016 Oct 10;34(29):3570-3575. doi: 10.1200/JCO.2016.68.4217. Review.

PMID:
27458309
3.

Data Sharing as Part of the Normal Scientific Process: A View from the Pharmaceutical Industry.

Vallance P, Freeman A, Stewart M.

PLoS Med. 2016 Jan 5;13(1):e1001936. doi: 10.1371/journal.pmed.1001936. eCollection 2016 Jan. No abstract available.

4.

Patrick Vallance: Inquisitive and geeky.

Vallance P.

BMJ. 2015 Mar 5;350:h1144. doi: 10.1136/bmj.h1144. No abstract available.

PMID:
25742697
5.

Secure use of individual patient data from clinical trials.

Vallance P, Chalmers I.

Lancet. 2013 Sep 28;382(9898):1073-4. doi: 10.1016/S0140-6736(13)62001-2. No abstract available.

PMID:
24075034
6.

Science as a public enterprise: the case for open data.

Boulton G, Rawlins M, Vallance P, Walport M.

Lancet. 2011 May 14;377(9778):1633-5. doi: 10.1016/S0140-6736(11)60647-8. No abstract available.

7.

Carriage of the V279F null allele within the gene encoding Lp-PLA₂ is protective from coronary artery disease in South Korean males.

Jang Y, Waterworth D, Lee JE, Song K, Kim S, Kim HS, Park KW, Cho HJ, Oh IY, Park JE, Lee BS, Ku HJ, Shin DJ, Lee JH, Jee SH, Han BG, Jang HY, Cho EY, Vallance P, Whittaker J, Cardon L, Mooser V.

PLoS One. 2011 Apr 5;6(4):e18208. doi: 10.1371/journal.pone.0018208.

8.

An audience with Patrick Vallance.

Vallance P.

Nat Rev Drug Discov. 2010 Nov;9(11):834. doi: 10.1038/nrd3307. Epub 2010 Oct 29. No abstract available.

PMID:
21030993
9.

The future is much closer collaboration between the pharmaceutical industry and academic medical centers.

Vallance P, Williams P, Dollery C.

Clin Pharmacol Ther. 2010 May;87(5):525-7. doi: 10.1038/clpt.2010.29. Review. No abstract available.

PMID:
20407455
10.

Regulation of the ADMA-DDAH system in endothelial cells: a novel mechanism for the sterol response element binding proteins, SREBP1c and -2.

Ivashchenko CY, Bradley BT, Ao Z, Leiper J, Vallance P, Johns DG.

Am J Physiol Heart Circ Physiol. 2010 Jan;298(1):H251-8. doi: 10.1152/ajpheart.00195.2009. Epub 2009 Nov 13.

11.

Immunolocalisation and activity of DDAH I and II in the heart and modification post-myocardial infarction.

Gray GA, Patrizio M, Sherry L, Miller AA, Malaki M, Wallace AF, Leiper JM, Vallance P.

Acta Histochem. 2010 Sep;112(5):413-23. doi: 10.1016/j.acthis.2009.02.009. Epub 2009 May 29.

PMID:
19481782
12.

Over-expression of GTP-cyclohydrolase 1 feedback regulatory protein attenuates LPS and cytokine-stimulated nitric oxide production.

Nandi M, Kelly P, Vallance P, Leiper J.

Vasc Med. 2008 Feb;13(1):29-36. doi: 10.1177/1358863X07085916.

PMID:
18372436
13.

Drug discovery and development in the age of molecular medicine.

Vallance P, Levick M.

Clin Pharmacol Ther. 2007 Oct;82(4):363-6. Review.

PMID:
17851574
14.

Isoform-specific regulation by N(G),N(G)-dimethylarginine dimethylaminohydrolase of rat serum asymmetric dimethylarginine and vascular endothelium-derived relaxing factor/NO.

Wang D, Gill PS, Chabrashvili T, Onozato ML, Raggio J, Mendonca M, Dennehy K, Li M, Modlinger P, Leiper J, Vallance P, Adler O, Leone A, Tojo A, Welch WJ, Wilcox CS.

Circ Res. 2007 Sep 14;101(6):627-35. Epub 2007 Aug 2.

PMID:
17673667
15.

Discovery of inhibitors of the pentein superfamily protein dimethylarginine dimethylaminohydrolase (DDAH), by virtual screening and hit analysis.

Hartzoulakis B, Rossiter S, Gill H, O'Hara B, Steinke E, Gane PJ, Hurtado-Guerrero R, Leiper JM, Vallance P, Rust JM, Selwood DL.

Bioorg Med Chem Lett. 2007 Jul 15;17(14):3953-6. Epub 2007 May 3.

PMID:
17543521
16.

Treatment of periodontitis and endothelial function.

Tonetti MS, D'Aiuto F, Nibali L, Donald A, Storry C, Parkar M, Suvan J, Hingorani AD, Vallance P, Deanfield J.

N Engl J Med. 2007 Mar 1;356(9):911-20. Erratum in: N Engl J Med. 2018 Jun 13;:null.

17.

The ADMA/DDAH pathway is a critical regulator of endothelial cell motility.

Wojciak-Stothard B, Torondel B, Tsang LY, Fleming I, Fisslthaler B, Leiper JM, Vallance P.

J Cell Sci. 2007 Mar 15;120(Pt 6):929-42. Epub 2007 Feb 27. Erratum in: J Cell Sci. 2007 Apr 15;120(Pt 8):1502.

18.

Disruption of methylarginine metabolism impairs vascular homeostasis.

Leiper J, Nandi M, Torondel B, Murray-Rust J, Malaki M, O'Hara B, Rossiter S, Anthony S, Madhani M, Selwood D, Smith C, Wojciak-Stothard B, Rudiger A, Stidwill R, McDonald NQ, Vallance P.

Nat Med. 2007 Feb;13(2):198-203. Epub 2007 Feb 4.

PMID:
17273169
19.

Asymmetric dimethylarginine in cerebral small vessel disease.

Khan U, Hassan A, Vallance P, Markus HS.

Stroke. 2007 Feb;38(2):411-3. Epub 2007 Jan 4.

PMID:
17204687
20.

Increasing dimethylarginine levels are associated with adverse clinical outcome in severe alcoholic hepatitis.

Mookerjee RP, Malaki M, Davies NA, Hodges SJ, Dalton RN, Turner C, Sen S, Williams R, Leiper J, Vallance P, Jalan R.

Hepatology. 2007 Jan;45(1):62-71.

PMID:
17187433

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