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Items: 1 to 20 of 113

1.

Gallium disrupts bacterial iron metabolism and has therapeutic effects in mice and humans with lung infections.

Goss CH, Kaneko Y, Khuu L, Anderson GD, Ravishankar S, Aitken ML, Lechtzin N, Zhou G, Czyz DM, McLean K, Olakanmi O, Shuman HA, Teresi M, Wilhelm E, Caldwell E, Salipante SJ, Hornick DB, Siehnel RJ, Becker L, Britigan BE, Singh PK.

Sci Transl Med. 2018 Sep 26;10(460). pii: eaat7520. doi: 10.1126/scitranslmed.aat7520.

PMID:
30257953
2.

GigA and GigB are Master Regulators of Antibiotic Resistance, Stress Responses, and Virulence in Acinetobacter baumannii.

Gebhardt MJ, Shuman HA.

J Bacteriol. 2017 Apr 25;199(10). pii: e00066-17. doi: 10.1128/JB.00066-17. Print 2017 May 15.

3.

Seeing red; the development of pON.mCherry, a broad-host range constitutive expression plasmid for Gram-negative bacteria.

Gebhardt MJ, Jacobson RK, Shuman HA.

PLoS One. 2017 Mar 3;12(3):e0173116. doi: 10.1371/journal.pone.0173116. eCollection 2017.

4.

A dual-targeting approach to inhibit Brucella abortus replication in human cells.

Czyż DM, Jain-Gupta N, Shuman HA, Crosson S.

Sci Rep. 2016 Oct 21;6:35835. doi: 10.1038/srep35835.

5.

Direct targeting of membrane fusion by SNARE mimicry: Convergent evolution of Legionella effectors.

Shi X, Halder P, Yavuz H, Jahn R, Shuman HA.

Proc Natl Acad Sci U S A. 2016 Aug 2;113(31):8807-12. doi: 10.1073/pnas.1608755113. Epub 2016 Jul 19.

6.

Genomic analysis of 38 Legionella species identifies large and diverse effector repertoires.

Burstein D, Amaro F, Zusman T, Lifshitz Z, Cohen O, Gilbert JA, Pupko T, Shuman HA, Segal G.

Nat Genet. 2016 Feb;48(2):167-75. doi: 10.1038/ng.3481. Epub 2016 Jan 11.

7.

Joint Transcriptional Control of Virulence and Resistance to Antibiotic and Environmental Stress in Acinetobacter baumannii.

Gebhardt MJ, Gallagher LA, Jacobson RK, Usacheva EA, Peterson LR, Zurawski DV, Shuman HA.

MBio. 2015 Nov 10;6(6):e01660-15. doi: 10.1128/mBio.01660-15.

8.

Diverse protist grazers select for virulence-related traits in Legionella.

Amaro F, Wang W, Gilbert JA, Anderson OR, Shuman HA.

ISME J. 2015 Jul;9(7):1607-18. doi: 10.1038/ismej.2014.248. Epub 2015 Jan 9.

9.

Genetic Manipulation of Acinetobacter baumannii.

Jacobs AC, Thompson MG, Gebhardt M, Corey BW, Yildirim S, Shuman HA, Zurawski DV.

Curr Protoc Microbiol. 2014 Nov 3;35:6G.2.1-11. doi: 10.1002/9780471729259.mc06g02s35.

PMID:
25367274
10.

Host-directed antimicrobial drugs with broad-spectrum efficacy against intracellular bacterial pathogens.

Czyż DM, Potluri LP, Jain-Gupta N, Riley SP, Martinez JJ, Steck TL, Crosson S, Shuman HA, Gabay JE.

MBio. 2014 Jul 29;5(4):e01534-14. doi: 10.1128/mBio.01534-14.

11.

Identification of novel Coxiella burnetii Icm/Dot effectors and genetic analysis of their involvement in modulating a mitogen-activated protein kinase pathway.

Lifshitz Z, Burstein D, Schwartz K, Shuman HA, Pupko T, Segal G.

Infect Immun. 2014 Sep;82(9):3740-52. doi: 10.1128/IAI.01729-14. Epub 2014 Jun 23.

12.

Analysis of the transcriptome of Legionella pneumophila hfq mutant reveals a new mobile genetic element.

Trigui H, Dudyk P, Sum J, Shuman HA, Faucher SP.

Microbiology. 2013 Aug;159(Pt 8):1649-60. doi: 10.1099/mic.0.067983-0. Epub 2013 May 31.

13.

Legionella pneumophila transcriptional response following exposure to CuO nanoparticles.

Lu J, Struewing I, Buse HY, Kou J, Shuman HA, Faucher SP, Ashbolt NJ.

Appl Environ Microbiol. 2013 Apr;79(8):2713-20. doi: 10.1128/AEM.03462-12. Epub 2013 Feb 15.

14.

Computational modeling and experimental validation of the Legionella and Coxiella virulence-related type-IVB secretion signal.

Lifshitz Z, Burstein D, Peeri M, Zusman T, Schwartz K, Shuman HA, Pupko T, Segal G.

Proc Natl Acad Sci U S A. 2013 Feb 19;110(8):E707-15. doi: 10.1073/pnas.1215278110. Epub 2013 Feb 4.

15.

In vitro derivation of macrophage from guinea pig bone marrow with human M-CSF.

Yu KO, Porcelli SA, Shuman HA.

J Immunol Methods. 2013 Mar 29;389(1-2):88-94. doi: 10.1016/j.jim.2013.01.005. Epub 2013 Jan 16.

PMID:
23333710
16.

Methods to study legionella transcriptome in vitro and in vivo.

Faucher SP, Shuman HA.

Methods Mol Biol. 2013;954:567-82. doi: 10.1007/978-1-62703-161-5_35.

PMID:
23150421
17.

A pathogen's journey in the host cell: Bridges between actin and traffic.

Franco IS, Shuman HA.

Bioarchitecture. 2012 Feb 1;2(2):38-42.

18.

The Legionella pneumophila effector VipA is an actin nucleator that alters host cell organelle trafficking.

Franco IS, Shohdy N, Shuman HA.

PLoS Pathog. 2012 Feb;8(2):e1002546. doi: 10.1371/journal.ppat.1002546. Epub 2012 Feb 23.

19.

Whole-genome sequence of the human pathogen Legionella pneumophila serogroup 12 strain 570-CO-H.

Amaro F, Gilbert JA, Owens S, Trimble W, Shuman HA.

J Bacteriol. 2012 Mar;194(6):1613-4. doi: 10.1128/JB.06626-11.

20.

Small Regulatory RNA and Legionella pneumophila.

Faucher SP, Shuman HA.

Front Microbiol. 2011 May 6;2:98. doi: 10.3389/fmicb.2011.00098. eCollection 2011.

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