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J Foot Surg. 1990 Jan-Feb;29(1):84-7.

Detrimental effects of cigarette smoking on lower extremity wound healing.

Author information

1
Department of Surgery, Podiatry Section Southwest Detroit Hospital/Westland Medical Center, Michigan.

Abstract

The authors review the detrimental effects of cigarette smoke and its constituents to normal physiology. Nicotine and carbon monoxide, principle components of cigarette smoke appear to exert an influence on wound repair by inhibiting epithelization, damaging blood cellular components, and creating a cellular hypoxia. Recommendations for perioperative cessation of smoking by the patient are made.

PMID:
2181017
[Indexed for MEDLINE]

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