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Items: 20

1.

Identification and Pharmacological Profile of an Indane Based Series of Ghrelin Receptor Full Agonists.

Gardelli C, Wada H, Ray A, Caffrey M, Llinas A, Shamovsky I, Tholander J, Larsson J, Sivars U, Hultin L, Andersson U, Sanganee HJ, Stenvall K, Leidvik B, Gedda K, Jinton L, Rydén Landergren M, Karabelas K.

J Med Chem. 2018 Jul 26;61(14):5974-5987. doi: 10.1021/acs.jmedchem.8b00322. Epub 2018 Jul 6.

PMID:
29909635
2.

Theoretical studies of the second step of the nitric oxide synthase reaction: Electron tunneling prevents uncoupling.

Shamovsky I, Belfield G, Lewis R, Narjes F, Ripa L, Tyrchan C, Öberg L, Sjö P.

J Inorg Biochem. 2018 Apr;181:28-40. doi: 10.1016/j.jinorgbio.2018.01.009. Epub 2018 Jan 10.

PMID:
29407906
3.

Mechanism of biofilm-mediated stress resistance and lifespan extension in C. elegans.

Smolentseva O, Gusarov I, Gautier L, Shamovsky I, DeFrancesco AS, Losick R, Nudler E.

Sci Rep. 2017 Aug 2;7(1):7137. doi: 10.1038/s41598-017-07222-8.

4.

Glycogen controls Caenorhabditis elegans lifespan and resistance to oxidative stress.

Gusarov I, Pani B, Gautier L, Smolentseva O, Eremina S, Shamovsky I, Katkova-Zhukotskaya O, Mironov A, Nudler E.

Nat Commun. 2017 Jun 19;8:15868. doi: 10.1038/ncomms15868.

5.

sRNA-Mediated Control of Transcription Termination in E. coli.

Sedlyarova N, Shamovsky I, Bharati BK, Epshtein V, Chen J, Gottesman S, Schroeder R, Nudler E.

Cell. 2016 Sep 22;167(1):111-121.e13. doi: 10.1016/j.cell.2016.09.004.

6.

Rates and mechanisms of bacterial mutagenesis from maximum-depth sequencing.

Jee J, Rasouly A, Shamovsky I, Akivis Y, Steinman SR, Mishra B, Nudler E.

Nature. 2016 Jun 30;534(7609):693-6. Epub 2016 Jun 22.

7.

The discovery of a selective and potent A2a agonist with extended lung retention.

Åstrand AB, Lamm Bergström E, Zhang H, Börjesson L, Söderdahl T, Wingren C, Jansson AH, Smailagic A, Johansson C, Bladh H, Shamovsky I, Tunek A, Drmota T.

Pharmacol Res Perspect. 2015 Jun;3(3):e00134. doi: 10.1002/prp2.134. Epub 2015 May 4.

8.

Theoretical studies of the mechanism of N-hydroxylation of primary aromatic amines by cytochrome P450 1A2: radicaloid or anionic?

Ripa L, Mee C, Sjö P, Shamovsky I.

Chem Res Toxicol. 2014 Feb 17;27(2):265-78. doi: 10.1021/tx400376u. Epub 2014 Jan 24.

PMID:
24410629
9.

Bacterial nitric oxide extends the lifespan of C. elegans.

Gusarov I, Gautier L, Smolentseva O, Shamovsky I, Eremina S, Mironov A, Nudler E.

Cell. 2013 Feb 14;152(4):818-30. doi: 10.1016/j.cell.2012.12.043.

10.

Theoretical studies of chemical reactivity of metabolically activated forms of aromatic amines toward DNA.

Shamovsky I, Ripa L, Blomberg N, Eriksson LA, Hansen P, Mee C, Tyrchan C, O'Donovan M, Sjö P.

Chem Res Toxicol. 2012 Oct 15;25(10):2236-52. doi: 10.1021/tx300313b. Epub 2012 Sep 20.

PMID:
22946514
11.

Explanation for main features of structure-genotoxicity relationships of aromatic amines by theoretical studies of their activation pathways in CYP1A2.

Shamovsky I, Ripa L, Börjesson L, Mee C, Nordén B, Hansen P, Hasselgren C, O'Donovan M, Sjö P.

J Am Chem Soc. 2011 Oct 12;133(40):16168-85. doi: 10.1021/ja206427u. Epub 2011 Sep 21.

PMID:
21894985
12.

Increasing selectivity of CC chemokine receptor 8 antagonists by engineering nondesolvation related interactions with the intended and off-target binding sites.

Shamovsky I, de Graaf C, Alderin L, Bengtsson M, Bladh H, Börjesson L, Connolly S, Dyke HJ, van den Heuvel M, Johansson H, Josefsson BG, Kristoffersson A, Linnanen T, Lisius A, Männikkö R, Nordén B, Price S, Ripa L, Rognan D, Rosendahl A, Skrinjar M, Urbahns K.

J Med Chem. 2009 Dec 10;52(23):7706-23. doi: 10.1021/jm900713y.

PMID:
19954248
13.

Targeting eEF1A by a Legionella pneumophila effector leads to inhibition of protein synthesis and induction of host stress response.

Shen X, Banga S, Liu Y, Xu L, Gao P, Shamovsky I, Nudler E, Luo ZQ.

Cell Microbiol. 2009 Jun;11(6):911-26. doi: 10.1111/j.1462-5822.2009.01301.x. Epub 2009 Feb 27.

14.

Isolation and characterization of the heat shock RNA 1.

Shamovsky I, Nudler E.

Methods Mol Biol. 2009;540:265-79. doi: 10.1007/978-1-59745-558-9_19.

15.

Modular RNA heats up.

Shamovsky I, Nudler E.

Mol Cell. 2008 Feb 29;29(4):415-7. doi: 10.1016/j.molcel.2008.02.001.

16.

Overcoming undesirable HERG potency of chemokine receptor antagonists using baseline lipophilicity relationships.

Shamovsky I, Connolly S, David L, Ivanova S, Nordén B, Springthorpe B, Urbahns K.

J Med Chem. 2008 Mar 13;51(5):1162-78. doi: 10.1021/jm070543k. Epub 2008 Feb 8.

PMID:
18257512
17.

New insights into the mechanism of heat shock response activation.

Shamovsky I, Nudler E.

Cell Mol Life Sci. 2008 Mar;65(6):855-61. doi: 10.1007/s00018-008-7458-y. Review.

PMID:
18239856
18.

Gene control by large noncoding RNAs.

Shamovsky I, Nudler E.

Sci STKE. 2006 Oct 3;2006(355):pe40. Review.

PMID:
17018852
19.

RNA-mediated response to heat shock in mammalian cells.

Shamovsky I, Ivannikov M, Kandel ES, Gershon D, Nudler E.

Nature. 2006 Mar 23;440(7083):556-60.

PMID:
16554823

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