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Items: 7


Regulation of hedgehog Ligand Expression by the N-End Rule Ubiquitin-Protein Ligase Hyperplastic Discs and the Drosophila GSK3β Homologue, Shaggy.

Moncrieff S, Moncan M, Scialpi F, Ditzel M.

PLoS One. 2015 Sep 3;10(9):e0136760. doi: 10.1371/journal.pone.0136760. eCollection 2015.


EDD, a ubiquitin-protein ligase of the N-end rule pathway, associates with spindle assembly checkpoint components and regulates the mitotic response to nocodazole.

Scialpi F, Mellis D, Ditzel M.

J Biol Chem. 2015 May 15;290(20):12585-94. doi: 10.1074/jbc.M114.625673. Epub 2015 Apr 1.


The E3 ubiquitin ligase WWP1 regulates ΔNp63-dependent transcription through Lys63 linkages.

Peschiaroli A, Scialpi F, Bernassola F, El Sherbini el S, Melino G.

Biochem Biophys Res Commun. 2010 Nov 12;402(2):425-30. doi: 10.1016/j.bbrc.2010.10.050. Epub 2010 Oct 15.


The F-box protein FBXO45 promotes the proteasome-dependent degradation of p73.

Peschiaroli A, Scialpi F, Bernassola F, Pagano M, Melino G.

Oncogene. 2009 Sep 3;28(35):3157-66. doi: 10.1038/onc.2009.177. Epub 2009 Jul 6.


Itch self-polyubiquitylation occurs through lysine-63 linkages.

Scialpi F, Malatesta M, Peschiaroli A, Rossi M, Melino G, Bernassola F.

Biochem Pharmacol. 2008 Dec 1;76(11):1515-21. doi: 10.1016/j.bcp.2008.07.028. Epub 2008 Jul 31.


Itch: a HECT-type E3 ligase regulating immunity, skin and cancer.

Melino G, Gallagher E, Aqeilan RI, Knight R, Peschiaroli A, Rossi M, Scialpi F, Malatesta M, Zocchi L, Browne G, Ciechanover A, Bernassola F.

Cell Death Differ. 2008 Jul;15(7):1103-12. doi: 10.1038/cdd.2008.60. Review.


Biochemical characterization of MLC1 protein in astrocytes and its association with the dystrophin-glycoprotein complex.

Ambrosini E, Serafini B, Lanciotti A, Tosini F, Scialpi F, Psaila R, Raggi C, Di Girolamo F, Petrucci TC, Aloisi F.

Mol Cell Neurosci. 2008 Mar;37(3):480-93. doi: 10.1016/j.mcn.2007.11.003. Epub 2007 Nov 17.


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