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Items: 1 to 20 of 26

1.

Structural and Biochemical Investigation of PglF from Campylobacter jejuni Reveals a New Mechanism for a Member of the Short Chain Dehydrogenase/Reductase Superfamily.

Riegert AS, Thoden JB, Schoenhofen IC, Watson DC, Young NM, Tipton PA, Holden HM.

Biochemistry. 2017 Nov 14;56(45):6030-6040. doi: 10.1021/acs.biochem.7b00910. Epub 2017 Nov 3.

2.

Biosynthesis of Legionaminic Acid and Its Incorporation Into Glycoconjugates.

Schoenhofen IC, Young NM, Gilbert M.

Methods Enzymol. 2017;597:187-207. doi: 10.1016/bs.mie.2017.06.042. Epub 2017 Sep 9.

PMID:
28935102
3.

Characterization of the dTDP-Fuc3N and dTDP-Qui3N biosynthetic pathways in Campylobacter jejuni 81116.

Li ZZ, Riegert AS, Goneau MF, Cunningham AM, Vinogradov E, Li J, Schoenhofen IC, Thoden JB, Holden HM, Gilbert M.

Glycobiology. 2017 Apr 1;27(4):358-369. doi: 10.1093/glycob/cww136.

4.

Tannerella forsythia strains display different cell-surface nonulosonic acids: biosynthetic pathway characterization and first insight into biological implications.

Friedrich V, Janesch B, Windwarder M, Maresch D, Braun ML, Megson ZA, Vinogradov E, Goneau MF, Sharma A, Altmann F, Messner P, Schoenhofen IC, Schäffer C.

Glycobiology. 2017 Apr 1;27(4):342-357. doi: 10.1093/glycob/cww129.

5.

Total Biosynthesis of Legionaminic Acid, a Bacterial Sialic Acid Analogue.

Hassan MI, Lundgren BR, Chaumun M, Whitfield DM, Clark B, Schoenhofen IC, Boddy CN.

Angew Chem Int Ed Engl. 2016 Sep 19;55(39):12018-21. doi: 10.1002/anie.201606006. Epub 2016 Aug 19.

PMID:
27538580
6.

Utilizing CMP-Sialic Acid Analogs to Unravel Neisseria gonorrhoeae Lipooligosaccharide-Mediated Complement Resistance and Design Novel Therapeutics.

Gulati S, Schoenhofen IC, Whitfield DM, Cox AD, Li J, St Michael F, Vinogradov EV, Stupak J, Zheng B, Ohnishi M, Unemo M, Lewis LA, Taylor RE, Landig CS, Diaz S, Reed GW, Varki A, Rice PA, Ram S.

PLoS Pathog. 2015 Dec 2;11(12):e1005290. doi: 10.1371/journal.ppat.1005290. eCollection 2015 Dec.

7.

Erratum to: Mass spectrometric analysis of products of metabolic glycan engineering with azido-modification of sialic acids.

Bodnar E, Raymond C, Lopez PG, Villacrés C, Butler M, Schoenhofen IC, Durocher Y, Perreault H.

Anal Bioanal Chem. 2015 Dec;407(30):9191-3. doi: 10.1007/s00216-015-9158-4. Epub 2015 Nov 9. No abstract available.

PMID:
26549112
8.

Mass spectrometric analysis of products of metabolic glycan engineering with azido-modification of sialic acids.

Bodnar E, Raymond C, Lopez PG, Villacrés C, Butler M, Schoenhofen IC, Durocher Y, Perreault H.

Anal Bioanal Chem. 2015 Dec;407(30):8945-58. doi: 10.1007/s00216-015-9010-x. Epub 2015 Sep 11. Erratum in: Anal Bioanal Chem. 2015 Dec;407(30):9191-3.

PMID:
26362153
9.

Sialyltransferases with enhanced legionaminic acid transferase activity for the preparation of analogs of sialoglycoconjugates.

Watson DC, Wakarchuk WW, Leclerc S, Schur MJ, Schoenhofen IC, Young NM, Gilbert M.

Glycobiology. 2015 Jul;25(7):767-73. doi: 10.1093/glycob/cwv017. Epub 2015 Apr 3.

PMID:
25840968
10.

Small-molecule inhibitors of the pseudaminic acid biosynthetic pathway: targeting motility as a key bacterial virulence factor.

Ménard R, Schoenhofen IC, Tao L, Aubry A, Bouchard P, Reid CW, Lachance P, Twine SM, Fulton KM, Cui Q, Hogues H, Purisima EO, Sulea T, Logan SM.

Antimicrob Agents Chemother. 2014 Dec;58(12):7430-40. doi: 10.1128/AAC.03858-14. Epub 2014 Sep 29.

11.

Identification and recombinant expression of anandamide hydrolyzing enzyme from Dictyostelium discoideum.

Neelamegan D, Schoenhofen IC, Richards JC, Cox AD.

BMC Microbiol. 2012 Jun 25;12:124. doi: 10.1186/1471-2180-12-124.

12.

The application of NMR spectroscopy to functional glycomics.

Brisson JR, Vinogradov E, McNally DJ, Khieu NH, Schoenhofen IC, Logan SM, Jarrell H.

Methods Mol Biol. 2010;600:155-73. doi: 10.1007/978-1-60761-454-8_11.

PMID:
19882127
13.

Structural and functional analysis of Campylobacter jejuni PseG: a udp-sugar hydrolase from the pseudaminic acid biosynthetic pathway.

Rangarajan ES, Proteau A, Cui Q, Logan SM, Potetinova Z, Whitfield D, Purisima EO, Cygler M, Matte A, Sulea T, Schoenhofen IC.

J Biol Chem. 2009 Jul 31;284(31):20989-1000. doi: 10.1074/jbc.M109.012351. Epub 2009 May 29.

14.

The engineering of bacteria bearing azido-pseudaminic acid-modified flagella.

Liu F, Aubry AJ, Schoenhofen IC, Logan SM, Tanner ME.

Chembiochem. 2009 May 25;10(8):1317-20. doi: 10.1002/cbic.200900018.

PMID:
19422007
15.

The CMP-legionaminic acid pathway in Campylobacter: biosynthesis involving novel GDP-linked precursors.

Schoenhofen IC, Vinogradov E, Whitfield DM, Brisson JR, Logan SM.

Glycobiology. 2009 Jul;19(7):715-25. doi: 10.1093/glycob/cwp039. Epub 2009 Mar 12.

PMID:
19282391
16.

Mechanistic studies on PseB of pseudaminic acid biosynthesis: a UDP-N-acetylglucosamine 5-inverting 4,6-dehydratase.

Morrison JP, Schoenhofen IC, Tanner ME.

Bioorg Chem. 2008 Dec;36(6):312-20. doi: 10.1016/j.bioorg.2008.08.004. Epub 2008 Oct 9.

PMID:
18845311
17.

CMP-pseudaminic acid is a natural potent inhibitor of PseB, the first enzyme of the pseudaminic acid pathway in Campylobacter jejuni and Helicobacter pylori.

McNally DJ, Schoenhofen IC, Houliston RS, Khieu NH, Whitfield DM, Logan SM, Jarrell HC, Brisson JR.

ChemMedChem. 2008 Jan;3(1):55-9. No abstract available.

PMID:
17893902
18.

Protein glycosylation in Campylobacter jejuni: partial suppression of pglF by mutation of pseC.

Guerry P, Ewing CP, Schoenhofen IC, Logan SM.

J Bacteriol. 2007 Sep;189(18):6731-3. Epub 2007 Jul 13.

19.

Identification of labile UDP-ketosugars in Helicobacter pylori, Campylobacter jejuni and Pseudomonas aeruginosa: key metabolites used to make glycan virulence factors.

McNally DJ, Schoenhofen IC, Mulrooney EF, Whitfield DM, Vinogradov E, Lam JS, Logan SM, Brisson JR.

Chembiochem. 2006 Dec;7(12):1865-8. No abstract available.

PMID:
17031886
20.

Elucidation of the CMP-pseudaminic acid pathway in Helicobacter pylori: synthesis from UDP-N-acetylglucosamine by a single enzymatic reaction.

Schoenhofen IC, McNally DJ, Brisson JR, Logan SM.

Glycobiology. 2006 Sep;16(9):8C-14C. Epub 2006 Jun 3.

PMID:
16751642

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