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Items: 1 to 20 of 417

1.

Reactive Oxygen Comes of Age: Mechanism-Based Therapy of Diabetic End-Organ Damage.

Elbatreek MH, Pachado MP, Cuadrado A, Jandeleit-Dahm K, Schmidt HHHW.

Trends Endocrinol Metab. 2019 May;30(5):312-327. doi: 10.1016/j.tem.2019.02.006. Epub 2019 Mar 27. Review.

2.

From single drug targets to synergistic network pharmacology in ischemic stroke.

Casas AI, Hassan AA, Larsen SJ, Gomez-Rangel V, Elbatreek M, Kleikers PWM, Guney E, Egea J, López MG, Baumbach J, Schmidt HHHW.

Proc Natl Acad Sci U S A. 2019 Apr 2;116(14):7129-7136. doi: 10.1073/pnas.1820799116. Epub 2019 Mar 20.

3.

Calcium-dependent blood-brain barrier breakdown by NOX5 limits postreperfusion benefit in stroke.

Casas AI, Kleikers PW, Geuss E, Langhauser F, Adler T, Busch DH, Gailus-Durner V, de Angelis MH, Egea J, Lopez MG, Kleinschnitz C, Schmidt HH.

J Clin Invest. 2019 Mar 18;130:1772-1778. doi: 10.1172/JCI124283. eCollection 2019 Mar 18.

4.

Achieving Complete Remission of Hepatocellular Carcinoma: A Significant Predictor for Recurrence-Free Survival after Liver Transplantation.

Bürger C, Maschmeier M, Hüsing-Kabar A, Wilms C, Köhler M, Schmidt M, Schmidt HH, Kabar I.

Can J Gastroenterol Hepatol. 2019 Jan 8;2019:5796074. doi: 10.1155/2019/5796074. eCollection 2019.

5.

E. coli gene regulatory networks are inconsistent with gene expression data.

Larsen SJ, Röttger R, Schmidt HHHW, Baumbach J.

Nucleic Acids Res. 2019 Jan 10;47(1):85-92. doi: 10.1093/nar/gky1176.

6.

Activation of Autophagy, Observed in Liver Tissues From Patients With Wilson Disease and From ATP7B-Deficient Animals, Protects Hepatocytes From Copper-Induced Apoptosis.

Polishchuk EV, Merolla A, Lichtmannegger J, Romano A, Indrieri A, Ilyechova EY, Concilli M, De Cegli R, Crispino R, Mariniello M, Petruzzelli R, Ranucci G, Iorio R, Pietrocola F, Einer C, Borchard S, Zibert A, Schmidt HH, Di Schiavi E, Puchkova LV, Franco B, Kroemer G, Zischka H, Polishchuk RS.

Gastroenterology. 2019 Mar;156(4):1173-1189.e5. doi: 10.1053/j.gastro.2018.11.032. Epub 2018 Nov 17.

PMID:
30452922
7.

Hepatocyte-like cells reveal novel role of SERPINA1 in transthyretin amyloidosis.

Niemietz C, Fleischhauer L, Sandfort V, Guttmann S, Zibert A, Schmidt HH.

J Cell Sci. 2018 Nov 26;131(23). pii: jcs219824. doi: 10.1242/jcs.219824.

PMID:
30333144
8.

Pictorial Representation of Illness and Self Measure (PRISM): A Novel Visual Instrument to Quantify Suffering in Liver Cirrhosis Patients and Liver Transplant Recipients.

Kabar I, Hüsing-Kabar A, Maschmeier M, Völler C, Dümke M, Schmidt HH, Heinzow H.

Ann Transplant. 2018 Sep 28;23:674-680. doi: 10.12659/AOT.910278.

9.

Acute allograft rejection in liver transplant recipients: Incidence, risk factors, treatment success, and impact on graft failure.

Dogan N, Hüsing-Kabar A, Schmidt HH, Cicinnati VR, Beckebaum S, Kabar I.

J Int Med Res. 2018 Sep;46(9):3979-3990. doi: 10.1177/0300060518785543. Epub 2018 Jul 12.

10.

Inotersen Treatment for Patients with Hereditary Transthyretin Amyloidosis.

Benson MD, Waddington-Cruz M, Berk JL, Polydefkis M, Dyck PJ, Wang AK, Planté-Bordeneuve V, Barroso FA, Merlini G, Obici L, Scheinberg M, Brannagan TH 3rd, Litchy WJ, Whelan C, Drachman BM, Adams D, Heitner SB, Conceição I, Schmidt HH, Vita G, Campistol JM, Gamez J, Gorevic PD, Gane E, Shah AM, Solomon SD, Monia BP, Hughes SG, Kwoh TJ, McEvoy BW, Jung SW, Baker BF, Ackermann EJ, Gertz MA, Coelho T.

N Engl J Med. 2018 Jul 5;379(1):22-31. doi: 10.1056/NEJMoa1716793.

11.

Patisiran, an RNAi Therapeutic, for Hereditary Transthyretin Amyloidosis.

Adams D, Gonzalez-Duarte A, O'Riordan WD, Yang CC, Ueda M, Kristen AV, Tournev I, Schmidt HH, Coelho T, Berk JL, Lin KP, Vita G, Attarian S, Planté-Bordeneuve V, Mezei MM, Campistol JM, Buades J, Brannagan TH 3rd, Kim BJ, Oh J, Parman Y, Sekijima Y, Hawkins PN, Solomon SD, Polydefkis M, Dyck PJ, Gandhi PJ, Goyal S, Chen J, Strahs AL, Nochur SV, Sweetser MT, Garg PP, Vaishnaw AK, Gollob JA, Suhr OB.

N Engl J Med. 2018 Jul 5;379(1):11-21. doi: 10.1056/NEJMoa1716153.

12.

Novel score predicts risk for cytomegalovirus infection in ulcerative colitis.

Nowacki TM, Bettenworth D, Meister T, Heidemann J, Lenze F, Schmidt HH, Heinzow HS.

J Clin Virol. 2018 Aug;105:103-108. doi: 10.1016/j.jcv.2018.06.002. Epub 2018 Jun 9.

PMID:
29940421
13.

Proximal Pathway Enrichment Analysis for Targeting Comorbid Diseases via Network Endopharmacology.

Aguirre-Plans J, Piñero J, Menche J, Sanz F, Furlong LI, Schmidt HHHW, Oliva B, Guney E.

Pharmaceuticals (Basel). 2018 Jun 22;11(3). pii: E61. doi: 10.3390/ph11030061.

14.

Is de novo hepatocellular carcinoma after transjugular intrahepatic portosystemic shunt increased?

Hüsing-Kabar A, Meister T, Köhler M, Domschke W, Kabar I, Wilms C, Hild B, Schmidt HH, Heinzow HS.

United European Gastroenterol J. 2018 Apr;6(3):413-421. doi: 10.1177/2050640617732886. Epub 2017 Sep 20.

15.

Functional Characterization of Novel ATP7B Variants for Diagnosis of Wilson Disease.

Guttmann S, Bernick F, Naorniakowska M, Michgehl U, Groba SR, Socha P, Zibert A, Schmidt HH.

Front Pediatr. 2018 Apr 30;6:106. doi: 10.3389/fped.2018.00106. eCollection 2018.

16.

[Transthyretin Familial Amyloid Polyneuropathy - Disease Profile of a Multisystem Disorder].

Niemietz C, Röcken C, Schilling M, Stypmann J, Uhlig CE, Schmidt HH.

Dtsch Med Wochenschr. 2018 Mar;143(6):e1. doi: 10.1055/a-0606-7749. Epub 2018 Apr 16. German. No abstract available.

PMID:
29660739
17.

[Transthyretin Familial Amyloid Polyneuropathy - Disease Profile of a Multisystem Disorder].

Niemietz C, Röcken C, Schilling M, Stypmann J, Uhlig CE, Schmidt HH.

Dtsch Med Wochenschr. 2018 Mar;143(6):427-430. doi: 10.1055/s-0043-123681. Epub 2018 Mar 15. German. Erratum in: Dtsch Med Wochenschr. 2018 Mar;143(6):e1.

PMID:
29544239
18.

Transcription Factor NRF2 as a Therapeutic Target for Chronic Diseases: A Systems Medicine Approach.

Cuadrado A, Manda G, Hassan A, Alcaraz MJ, Barbas C, Daiber A, Ghezzi P, León R, López MG, Oliva B, Pajares M, Rojo AI, Robledinos-Antón N, Valverde AM, Guney E, Schmidt HHHW.

Pharmacol Rev. 2018 Apr;70(2):348-383. doi: 10.1124/pr.117.014753. Review.

19.

A diseasome cluster-based drug repurposing of soluble guanylate cyclase activators from smooth muscle relaxation to direct neuroprotection.

Langhauser F, Casas AI, Dao VT, Guney E, Menche J, Geuss E, Kleikers PWM, López MG, Barabási AL, Kleinschnitz C, Schmidt HHHW.

NPJ Syst Biol Appl. 2018 Feb 5;4:8. doi: 10.1038/s41540-017-0039-7. eCollection 2018.

20.

Organic cation transporter 3 mediates cisplatin and copper cross-resistance in hepatoma cells.

Guttmann S, Chandhok G, Groba SR, Niemietz C, Sauer V, Gomes A, Ciarimboli G, Karst U, Zibert A, Schmidt HH.

Oncotarget. 2017 Dec 12;9(1):743-754. doi: 10.18632/oncotarget.23142. eCollection 2018 Jan 2.

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