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Items: 1 to 20 of 44


Mitotic spindle association of TACC3 requires Aurora-A-dependent stabilization of a cryptic α-helix.

Burgess SG, Mukherjee M, Sabir S, Joseph N, Gutiérrez-Caballero C, Richards MW, Huguenin-Dezot N, Chin JW, Kennedy EJ, Pfuhl M, Royle SJ, Gergely F, Bayliss R.

EMBO J. 2018 Apr 13;37(8). pii: e97902. doi: 10.15252/embj.201797902. Epub 2018 Mar 6.


New tools for "hot-wiring" clathrin-mediated endocytosis with temporal and spatial precision.

Wood LA, Larocque G, Clarke NI, Sarkar S, Royle SJ.

J Cell Biol. 2017 Dec 4;216(12):4351-4365. doi: 10.1083/jcb.201702188. Epub 2017 Sep 27.


FGFR3-TACC3 cancer gene fusions cause mitotic defects by removal of endogenous TACC3 from the mitotic spindle.

Sarkar S, Ryan EL, Royle SJ.

Open Biol. 2017 Aug;7(8). pii: 170080. doi: 10.1098/rsob.170080.


Congressing kinetochores progressively load Ska complexes to prevent force-dependent detachment.

Auckland P, Clarke NI, Royle SJ, McAinsh AD.

J Cell Biol. 2017 Jun 5;216(6):1623-1639. doi: 10.1083/jcb.201607096. Epub 2017 May 11.


Microtubule organization within mitotic spindles revealed by serial block face scanning electron microscopy and image analysis.

Nixon FM, Honnor TR, Clarke NI, Starling GP, Beckett AJ, Johansen AM, Brettschneider JA, Prior IA, Royle SJ.

J Cell Sci. 2017 May 15;130(10):1845-1855. doi: 10.1242/jcs.203877. Epub 2017 Apr 7.


The mesh is a network of microtubule connectors that stabilizes individual kinetochore fibers of the mitotic spindle.

Nixon FM, Gutiérrez-Caballero C, Hood FE, Booth DG, Prior IA, Royle SJ.

Elife. 2015 Jun 19;4. doi: 10.7554/eLife.07635.


A novel disorder reveals clathrin heavy chain-22 is essential for human pain and touch development.

Nahorski MS, Al-Gazali L, Hertecant J, Owen DJ, Borner GH, Chen YC, Benn CL, Carvalho OP, Shaikh SS, Phelan A, Robinson MS, Royle SJ, Woods CG.

Brain. 2015 Aug;138(Pt 8):2147-60. doi: 10.1093/brain/awv149. Epub 2015 Jun 11.


Hsp72 is targeted to the mitotic spindle by Nek6 to promote K-fiber assembly and mitotic progression.

O'Regan L, Sampson J, Richards MW, Knebel A, Roth D, Hood FE, Straube A, Royle SJ, Bayliss R, Fry AM.

J Cell Biol. 2015 May 11;209(3):349-58. doi: 10.1083/jcb.201409151. Epub 2015 May 4.


Zero tolerance: amphipathic helices in endocytosis.

Wood LA, Royle SJ.

Dev Cell. 2015 Apr 20;33(2):119-20. doi: 10.1016/j.devcel.2015.04.007.


TACC3-ch-TOG track the growing tips of microtubules independently of clathrin and Aurora-A phosphorylation.

Gutiérrez-Caballero C, Burgess SG, Bayliss R, Royle SJ.

Biol Open. 2015 Jan 16;4(2):170-9. doi: 10.1242/bio.201410843.


Super-duper resolution imaging of mitotic microtubules.

Royle SJ.

Nat Rev Mol Cell Biol. 2015 Feb;16(2):67. doi: 10.1038/nrm3937. Epub 2015 Jan 5. No abstract available.


Presynaptic clathrin levels are a limiting factor for synaptic transmission.

López-Murcia FJ, Royle SJ, Llobet A.

J Neurosci. 2014 Jun 18;34(25):8618-29. doi: 10.1523/JNEUROSCI.5081-13.2014.


Non-specificity of Pitstop 2 in clathrin-mediated endocytosis.

Willox AK, Sahraoui YM, Royle SJ.

Biol Open. 2014 Apr 4;3(5):326-31. doi: 10.1242/bio.20147955.


An unmet actin requirement explains the mitotic inhibition of clathrin-mediated endocytosis.

Kaur S, Fielding AB, Gassner G, Carter NJ, Royle SJ.

Elife. 2014 Feb 18;3:e00829. doi: 10.7554/eLife.00829.


Studying kinetochore-fiber ultrastructure using correlative light-electron microscopy.

Booth DG, Cheeseman LP, Prior IA, Royle SJ.

Methods Cell Biol. 2013;115:327-342. doi: 10.1016/B978-0-12-407757-7.00020-7.


Protein adaptation: mitotic functions for membrane trafficking proteins.

Royle SJ.

Nat Rev Mol Cell Biol. 2013 Sep;14(9):592-9. doi: 10.1038/nrm3641. Epub 2013 Aug 14. Review.


Coordination of adjacent domains mediates TACC3-ch-TOG-clathrin assembly and mitotic spindle binding.

Hood FE, Williams SJ, Burgess SG, Richards MW, Roth D, Straube A, Pfuhl M, Bayliss R, Royle SJ.

J Cell Biol. 2013 Aug 5;202(3):463-78. doi: 10.1083/jcb.201211127.


Specific removal of TACC3-ch-TOG-clathrin at metaphase deregulates kinetochore fiber tension.

Cheeseman LP, Harry EF, McAinsh AD, Prior IA, Royle SJ.

J Cell Sci. 2013 May 1;126(Pt 9):2102-13. doi: 10.1242/jcs.124834. Epub 2013 Mar 26.


Mitotic inhibition of clathrin-mediated endocytosis.

Fielding AB, Royle SJ.

Cell Mol Life Sci. 2013 Sep;70(18):3423-33. doi: 10.1007/s00018-012-1250-8. Epub 2013 Jan 11. Review.


Stonin 2 is a major adaptor protein for clathrin-mediated synaptic vesicle retrieval.

Willox AK, Royle SJ.

Curr Biol. 2012 Aug 7;22(15):1435-9. doi: 10.1016/j.cub.2012.05.048. Epub 2012 Jun 21.

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