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Items: 1 to 20 of 440

1.

Preclinical candidate for the treatment of visceral leishmaniasis that acts through proteasome inhibition.

Wyllie S, Brand S, Thomas M, De Rycker M, Chung CW, Pena I, Bingham RP, Bueren-Calabuig JA, Cantizani J, Cebrian D, Craggs PD, Ferguson L, Goswami P, Hobrath J, Howe J, Jeacock L, Ko EJ, Korczynska J, MacLean L, Manthri S, Martinez MS, Mata-Cantero L, Moniz S, Nühs A, Osuna-Cabello M, Pinto E, Riley J, Robinson S, Rowland P, Simeons FRC, Shishikura Y, Spinks D, Stojanovski L, Thomas J, Thompson S, Viayna Gaza E, Wall RJ, Zuccotto F, Horn D, Ferguson MAJ, Fairlamb AH, Fiandor JM, Martin J, Gray DW, Miles TJ, Gilbert IH, Read KD, Marco M, Wyatt PG.

Proc Natl Acad Sci U S A. 2019 Apr 8. pii: 201820175. doi: 10.1073/pnas.1820175116. [Epub ahead of print]

2.

Stratification of asthma phenotypes by airway proteomic signatures.

Schofield JPR, Burg D, Nicholas B, Strazzeri F, Brandsma J, Staykova D, Folisi C, Bansal AT, Xian Y, Guo Y, Rowe A, Corfield J, Wilson S, Ward J, Lutter R, Shaw DE, Bakke PS, Caruso M, Dahlen SE, Fowler SJ, Horváth I, Howarth P, Krug N, Montuschi P, Sanak M, Sandström T, Sun K, Pandis I, Riley J, Auffray C, De Meulder B, Lefaudeux D, Sousa AR, Adcock IM, Chung KF, Sterk PJ, Skipp PJ, Djukanović R; U-BIOPRED Study Group.

J Allergy Clin Immunol. 2019 Mar 27. pii: S0091-6749(19)30415-4. doi: 10.1016/j.jaci.2019.03.013. [Epub ahead of print]

PMID:
30928653
3.

Deep Brain Stimulation for Parkinson Disease.

Kogan M, McGuire M, Riley J.

Neurosurg Clin N Am. 2019 Apr;30(2):137-146. doi: 10.1016/j.nec.2019.01.001. Review.

PMID:
30898266
4.

Lysyl-tRNA synthetase as a drug target in malaria and cryptosporidiosis.

Baragaña B, Forte B, Choi R, Nakazawa Hewitt S, Bueren-Calabuig JA, Pisco JP, Peet C, Dranow DM, Robinson DA, Jansen C, Norcross NR, Vinayak S, Anderson M, Brooks CF, Cooper CA, Damerow S, Delves M, Dowers K, Duffy J, Edwards TE, Hallyburton I, Horst BG, Hulverson MA, Ferguson L, Jiménez-Díaz MB, Jumani RS, Lorimer DD, Love MS, Maher S, Matthews H, McNamara CW, Miller P, O'Neill S, Ojo KK, Osuna-Cabello M, Pinto E, Post J, Riley J, Rottmann M, Sanz LM, Scullion P, Sharma A, Shepherd SM, Shishikura Y, Simeons FRC, Stebbins EE, Stojanovski L, Straschil U, Tamaki FK, Tamjar J, Torrie LS, Vantaux A, Witkowski B, Wittlin S, Yogavel M, Zuccotto F, Angulo-Barturen I, Sinden R, Baum J, Gamo FJ, Mäser P, Kyle DE, Winzeler EA, Myler PJ, Wyatt PG, Floyd D, Matthews D, Sharma A, Striepen B, Huston CD, Gray DW, Fairlamb AH, Pisliakov AV, Walpole C, Read KD, Van Voorhis WC, Gilbert IH.

Proc Natl Acad Sci U S A. 2019 Apr 2;116(14):7015-7020. doi: 10.1073/pnas.1814685116. Epub 2019 Mar 20.

5.

Discovery of Soft-Drug Topical Tool Modulators of Sphingosine-1-phosphate Receptor 1 (S1PR1).

Bell M, Foley D, Naylor C, Wood G, Robinson C, Riley J, Epemolu O, Ellis L, Scullion P, Shishikura Y, Osuna-Cabello M, Ferguson L, Pinto E, Fletcher D, Katz E, McLean WHI, Wyatt P, Read KD, Woodland A.

ACS Med Chem Lett. 2019 Feb 14;10(3):341-347. doi: 10.1021/acsmedchemlett.8b00616. eCollection 2019 Mar 14.

6.

Understanding the factors associated with patients with dementia achieving their preferred place of death: a retrospective cohort study.

Wiggins N, Droney J, Mohammed K, Riley J, Sleeman KE.

Age Ageing. 2019 Feb 26. pii: afz015. doi: 10.1093/ageing/afz015. [Epub ahead of print]

PMID:
30806452
7.

Cerebral vasomotor reactivity during hypo- and hypercapnia across the adult lifespan.

Tomoto T, Riley J, Turner M, Zhang R, Tarumi T.

J Cereb Blood Flow Metab. 2019 Feb 15:271678X19828327. doi: 10.1177/0271678X19828327. [Epub ahead of print]

PMID:
30764704
8.

Fundamental clinical skills of adult cardiopulmonary bypass: results of the 2017 national survey.

Searles B, Darling E, Riley J, Wiles JR.

Perfusion. 2018 Dec 22:267659118816036. doi: 10.1177/0267659118816036. [Epub ahead of print]

PMID:
30582403
9.

Identification of GSK3186899/DDD853651 as a Preclinical Development Candidate for the Treatment of Visceral Leishmaniasis.

Thomas MG, De Rycker M, Ajakane M, Albrecht S, Álvarez-Pedraglio AI, Boesche M, Brand S, Campbell L, Cantizani-Perez J, Cleghorn LAT, Copley RCB, Crouch SD, Daugan A, Drewes G, Ferrer S, Ghidelli-Disse S, Gonzalez S, Gresham SL, Hill AP, Hindley SJ, Lowe RM, MacKenzie CJ, MacLean L, Manthri S, Martin F, Miguel-Siles J, Nguyen VL, Norval S, Osuna-Cabello M, Woodland A, Patterson S, Pena I, Quesada-Campos MT, Reid IH, Revill C, Riley J, Ruiz-Gomez JR, Shishikura Y, Simeons FRC, Smith A, Smith VC, Spinks D, Stojanovski L, Thomas J, Thompson S, Underwood T, Gray DW, Fiandor JM, Gilbert IH, Wyatt PG, Read KD, Miles TJ.

J Med Chem. 2019 Feb 14;62(3):1180-1202. doi: 10.1021/acs.jmedchem.8b01218. Epub 2018 Dec 20.

10.

Ice pack-induced perniosis: a rare and underrecognized association.

Tran D, Riley J, Xiao A, Jay S, Shitabata P, Nami N.

Cutis. 2018 Nov;102(5):E24-E26.

PMID:
30566562
11.

Clinically applicable delineation of the pallidal sensorimotor region in patients with advanced Parkinson's disease: study of probabilistic and deterministic tractography.

Muller J, Alizadeh M, Mohamed FB, Riley J, Pearce JJ, Trieu B, Liang TW, Romo V, Sharan A, Wu C.

J Neurosurg. 2018 Dec 1:1-12. doi: 10.3171/2018.7.JNS18541. [Epub ahead of print]

PMID:
30554176
12.

Eosinophilic asthma, according to a blood eosinophil criterion, is associated with disease severity and lack of control among underprivileged urban Brazilians.

Lima-Matos A, Ponte EV, de Jesus JPV, Almeida PCA, Lima VB, Kwon N, Riley J, de Mello LM, Cruz ÁA.

Respir Med. 2018 Dec;145:95-100. doi: 10.1016/j.rmed.2018.10.025. Epub 2018 Oct 23.

PMID:
30509723
13.

Concomitant fibrofolliculoma and trichodiscoma on the abdomen.

Riley J, Athalye L, Tran D, Fogelson S, Shitabata P.

Cutis. 2018 Oct;102(4):E30-E32.

PMID:
30489570
14.

Free-hand transperineal prostate biopsy provides acceptable cancer detection and minimizes risk of infection: evolving experience with a 10-sector template.

Ristau BT, Allaway M, Cendo D, Hart J, Riley J, Parousis V, Albertsen PC.

Urol Oncol. 2018 Dec;36(12):528.e15-528.e20. doi: 10.1016/j.urolonc.2018.09.013. Epub 2018 Nov 13.

PMID:
30446447
15.

Corrigendum to 'Role of cardiopulmonary exercise testing in clinical stratification in heart failure. A position paper from the Committee on Exercise Physiology and Training of the Heart Failure Association of the European Society of Cardiology' [Eur J Heart Fail 2018;20:3-15].

Corrà U, Agostoni PG, Anker SD, Coats AJS, Crespo Leiro MG, de Boer RA, Harjola VP, Hill L, Lainscak M, Lund LH, Metra M, Ponikowski P, Riley J, Seferović PM, Piepoli MF.

Eur J Heart Fail. 2018 Oct;20(10):1501. doi: 10.1002/ejhf.1186. Epub 2018 Mar 25. No abstract available.

PMID:
30303623
16.

Discovery of super soft-drug modulators of sphingosine-1-phosphate receptor 1.

Bell M, Foley D, Naylor C, Robinson C, Riley J, Epemolu O, Scullion P, Shishikura Y, Katz E, McLean WHI, Wyatt P, Read KD, Woodland A.

Bioorg Med Chem Lett. 2018 Oct 15;28(19):3255-3259. doi: 10.1016/j.bmcl.2018.07.044. Epub 2018 Jul 30.

17.

2,4-Diamino-6-methylpyrimidines for the potential treatment of Chagas' disease.

Thomas MG, De Rycker M, Cotillo Torrejon I, Thomas J, Riley J, Spinks D, Read KD, Miles TJ, Gilbert IH, Wyatt PG.

Bioorg Med Chem Lett. 2018 Oct 1;28(18):3025-3030. doi: 10.1016/j.bmcl.2018.08.005. Epub 2018 Aug 3.

PMID:
30104093
18.

Chemical synthesis, characterisation and in vitro and in vivo metabolism of the synthetic opioid MT-45 and its newly identified fluorinated analogue 2F-MT-45 with metabolite confirmation in urine samples from known drug users.

McKenzie C, Sutcliffe OB, Read KD, Scullion P, Epemolu O, Fletcher D, Helander A, Beck O, Rylski A, Antonides LH, Riley J, Smith SA, Nic Daeid N.

Forensic Toxicol. 2018;36(2):359-374. doi: 10.1007/s11419-018-0413-1. Epub 2018 Apr 5.

19.

Identification of Morpholino Thiophenes as Novel Mycobacterium tuberculosis Inhibitors, Targeting QcrB.

Cleghorn LAT, Ray PC, Odingo J, Kumar A, Wescott H, Korkegian A, Masquelin T, Lopez Moure A, Wilson C, Davis S, Huggett M, Turner P, Smith A, Epemolu O, Zuccotto F, Riley J, Scullion P, Shishikura Y, Ferguson L, Rullas J, Guijarro L, Read KD, Green SR, Hipskind P, Parish T, Wyatt PG.

J Med Chem. 2018 Aug 9;61(15):6592-6608. doi: 10.1021/acs.jmedchem.8b00172. Epub 2018 Jul 26.

20.

Digital Health Intervention for Asthma: Patient-Reported Value and Usability.

Merchant R, Inamdar R, Henderson K, Barrett M, Su JG, Riley J, Van Sickle D, Stempel D.

JMIR Mhealth Uhealth. 2018 Jun 4;6(6):e133. doi: 10.2196/mhealth.7362.

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