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Items: 20

1.

Short-term dietary methionine supplementation affects one-carbon metabolism and DNA methylation in the mouse gut and leads to altered microbiome profiles, barrier function, gene expression and histomorphology.

Miousse IR, Pathak R, Garg S, Skinner CM, Melnyk S, Pavliv O, Hendrickson H, Landes RD, Lumen A, Tackett AJ, Deutz NEP, Hauer-Jensen M, Koturbash I.

Genes Nutr. 2017 Sep 6;12:22. doi: 10.1186/s12263-017-0576-0. eCollection 2017.

2.

Effects of Obesity on Pro-Oxidative Conditions and DNA Damage in Liver of DMBA-Induced Mammary Carcinogenesis Models.

Melnyk S, Korourian S, Levy JW, Pavliv O, Evans T, Hakkak R.

Metabolites. 2017 Jun 8;7(2). pii: E26. doi: 10.3390/metabo7020026.

3.

Overexpression of LINE-1 Retrotransposons in Autism Brain.

Shpyleva S, Melnyk S, Pavliv O, Pogribny I, Jill James S.

Mol Neurobiol. 2018 Feb;55(2):1740-1749. doi: 10.1007/s12035-017-0421-x. Epub 2017 Feb 20.

PMID:
28220356
4.

Effects of local irradiation combined with sunitinib on early remodeling, mitochondria, and oxidative stress in the rat heart.

Sridharan V, Thomas CJ, Cao M, Melnyk SB, Pavliv O, Joseph J, Singh SP, Sharma S, Moros EG, Boerma M.

Radiother Oncol. 2016 May;119(2):259-64. doi: 10.1016/j.radonc.2016.03.027. Epub 2016 Apr 9.

5.

Radiation-induced changes in DNA methylation of repetitive elements in the mouse heart.

Koturbash I, Miousse IR, Sridharan V, Nzabarushimana E, Skinner CM, Melnyk SB, Pavliv O, Hauer-Jensen M, Nelson GA, Boerma M.

Mutat Res. 2016 May;787:43-53. doi: 10.1016/j.mrfmmm.2016.02.009. Epub 2016 Mar 2.

6.

A tocotrienol-enriched formulation protects against radiation-induced changes in cardiac mitochondria without modifying late cardiac function or structure.

Sridharan V, Tripathi P, Aykin-Burns N, Krager KJ, Sharma SK, Moros EG, Melnyk SB, Pavliv O, Hauer-Jensen M, Boerma M.

Radiat Res. 2015 Mar;183(3):357-66. doi: 10.1667/RR13915.1. Epub 2015 Feb 24.

7.

Elevated 5-hydroxymethylcytosine in the Engrailed-2 (EN-2) promoter is associated with increased gene expression and decreased MeCP2 binding in autism cerebellum.

James SJ, Shpyleva S, Melnyk S, Pavliv O, Pogribny IP.

Transl Psychiatry. 2014 Oct 7;4:e460. doi: 10.1038/tp.2014.87.

8.

Oxidative stress induces mitochondrial dysfunction in a subset of autism lymphoblastoid cell lines in a well-matched case control cohort.

Rose S, Frye RE, Slattery J, Wynne R, Tippett M, Pavliv O, Melnyk S, James SJ.

PLoS One. 2014 Jan 8;9(1):e85436. doi: 10.1371/journal.pone.0085436. eCollection 2014.

9.

Dietary intake and plasma levels of choline and betaine in children with autism spectrum disorders.

Hamlin JC, Pauly M, Melnyk S, Pavliv O, Starrett W, Crook TA, James SJ.

Autism Res Treat. 2013;2013:578429. doi: 10.1155/2013/578429. Epub 2013 Dec 16.

10.

Effectiveness of methylcobalamin and folinic Acid treatment on adaptive behavior in children with autistic disorder is related to glutathione redox status.

Frye RE, Melnyk S, Fuchs G, Reid T, Jernigan S, Pavliv O, Hubanks A, Gaylor DW, Walters L, James SJ.

Autism Res Treat. 2013;2013:609705. doi: 10.1155/2013/609705. Epub 2013 Oct 12.

11.

Complex epigenetic regulation of engrailed-2 (EN-2) homeobox gene in the autism cerebellum.

James SJ, Shpyleva S, Melnyk S, Pavliv O, Pogribny IP.

Transl Psychiatry. 2013 Feb 19;3:e232. doi: 10.1038/tp.2013.8.

12.

Intracellular and extracellular redox status and free radical generation in primary immune cells from children with autism.

Rose S, Melnyk S, Trusty TA, Pavliv O, Seidel L, Li J, Nick T, James SJ.

Autism Res Treat. 2012;2012:986519. doi: 10.1155/2012/986519. Epub 2011 Nov 24.

13.

Evidence of oxidative damage and inflammation associated with low glutathione redox status in the autism brain.

Rose S, Melnyk S, Pavliv O, Bai S, Nick TG, Frye RE, James SJ.

Transl Psychiatry. 2012 Jul 10;2:e134. doi: 10.1038/tp.2012.61.

14.

Metabolic imbalance associated with methylation dysregulation and oxidative damage in children with autism.

Melnyk S, Fuchs GJ, Schulz E, Lopez M, Kahler SG, Fussell JJ, Bellando J, Pavliv O, Rose S, Seidel L, Gaylor DW, James SJ.

J Autism Dev Disord. 2012 Mar;42(3):367-77. doi: 10.1007/s10803-011-1260-7.

15.

A functional polymorphism in the reduced folate carrier gene and DNA hypomethylation in mothers of children with autism.

James SJ, Melnyk S, Jernigan S, Pavliv O, Trusty T, Lehman S, Seidel L, Gaylor DW, Cleves MA.

Am J Med Genet B Neuropsychiatr Genet. 2010 Sep;153B(6):1209-20. doi: 10.1002/ajmg.b.31094.

16.

Cellular and mitochondrial glutathione redox imbalance in lymphoblastoid cells derived from children with autism.

James SJ, Rose S, Melnyk S, Jernigan S, Blossom S, Pavliv O, Gaylor DW.

FASEB J. 2009 Aug;23(8):2374-83. doi: 10.1096/fj.08-128926. Epub 2009 Mar 23.

17.

Efficacy of methylcobalamin and folinic acid treatment on glutathione redox status in children with autism.

James SJ, Melnyk S, Fuchs G, Reid T, Jernigan S, Pavliv O, Hubanks A, Gaylor DW.

Am J Clin Nutr. 2009 Jan;89(1):425-30. doi: 10.3945/ajcn.2008.26615. Epub 2008 Dec 3.

18.

Induction of oxidative stress and DNA damage in rat brain by a folate/methyl-deficient diet.

Bagnyukova TV, Powell CL, Pavliv O, Tryndyak VP, Pogribny IP.

Brain Res. 2008 Oct 27;1237:44-51. doi: 10.1016/j.brainres.2008.07.073. Epub 2008 Jul 29.

PMID:
18694737
19.

Interaction of the conserved oligomeric Golgi complex with t-SNARE Syntaxin5a/Sed5 enhances intra-Golgi SNARE complex stability.

Shestakova A, Suvorova E, Pavliv O, Khaidakova G, Lupashin V.

J Cell Biol. 2007 Dec 17;179(6):1179-92.

20.

Cog1p plays a central role in the organization of the yeast conserved oligomeric Golgi complex.

Fotso P, Koryakina Y, Pavliv O, Tsiomenko AB, Lupashin VV.

J Biol Chem. 2005 Jul 29;280(30):27613-23. Epub 2005 Jun 2.

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