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Items: 1 to 20 of 36


Phenotypic Screen for Cardiac Regeneration Identifies Molecules with Differential Activity in Human Epicardium-Derived Cells versus Cardiac Fibroblasts.

Paunovic AI, Drowley L, Nordqvist A, Ericson E, Mouchet E, Jonebring A, Grönberg G, Kvist AJ, Engkvist O, Brown MR, Gedda K, Goumans MJ, Wang QD, Plowright AT.

ACS Chem Biol. 2017 Jan 20;12(1):132-141. doi: 10.1021/acschembio.6b00683. Epub 2016 Nov 30.


Structure-Based Drug Design of Mineralocorticoid Receptor Antagonists to Explore Oxosteroid Receptor Selectivity.

Nordqvist A, O'Mahony G, Fridén-Saxin M, Fredenwall M, Hogner A, Granberg KL, Aagaard A, Bäckström S, Gunnarsson A, Kaminski T, Xue Y, Dellsén A, Hansson E, Hansson P, Ivarsson I, Karlsson U, Bamberg K, Hermansson M, Georgsson J, Lindmark B, Edman K.

ChemMedChem. 2017 Jan 5;12(1):50-65. doi: 10.1002/cmdc.201600529. Epub 2016 Dec 15.


Predicting the relative binding affinity of mineralocorticoid receptor antagonists by density functional methods.

Roos K, Hogner A, Ogg D, Packer MJ, Hansson E, Granberg KL, Evertsson E, Nordqvist A.

J Comput Aided Mol Des. 2015 Dec;29(12):1109-22. doi: 10.1007/s10822-015-9880-1. Epub 2015 Nov 16.


Correction to GPR103 Antagonists Demonstrating Anorexigenic Activity in Vivo: Design and Development of Pyrrolo[2,3-c]pyridines That Mimic the C-Terminal Arg-Phe Motif of QRFP26.

Georgsson J, Bergström F, Nordqvist A, Watson MJ, Blundell CD, Johansson MJ, Petersson AU, Yuan ZQ, Zhou Y, Kristensson L, Kakol-Palm D, Tyrchan C, Wellner E, Bauer U, Brodin P, Svensson Henriksson A.

J Med Chem. 2015 May 14;58(9):4086. doi: 10.1021/acs.jmedchem.5b00479. Epub 2015 Apr 15. No abstract available.


GPR103 antagonists demonstrating anorexigenic activity in vivo: design and development of pyrrolo[2,3-c]pyridines that mimic the C-terminal Arg-Phe motif of QRFP26.

Georgsson J, Bergström F, Nordqvist A, Watson MJ, Blundell CD, Johansson MJ, Petersson AU, Yuan ZQ, Zhou Y, Kristensson L, Kakol-Palm D, Tyrchan C, Wellner E, Bauer U, Brodin P, Svensson Henriksson A.

J Med Chem. 2014 Jul 24;57(14):5935-48. doi: 10.1021/jm401951t. Epub 2014 Jul 2. Erratum in: J Med Chem. 2015 May 14;58(9):4086.


New Hits as Antagonists of GPR103 Identified by HTS.

Nordqvist A, Kristensson L, Johansson KE, Isaksson da Silva K, Fex T, Tyrchan C, Svensson Henriksson A, Nilsson K.

ACS Med Chem Lett. 2014 Feb 22;5(5):527-32. doi: 10.1021/ml400519h. eCollection 2014 May 8.


Patients with shoulder impingement remain satisfied 6 years after arthroscopic subacromial decompression: a prospective study of 46 patients.

Lunsjö K, Bengtsson M, Nordqvist A, Abu-Zidan FM.

Acta Orthop. 2011 Dec;82(6):711-3. doi: 10.3109/17453674.2011.623571. Epub 2011 Oct 17.


Synthesis of functionalized cinnamaldehyde derivatives by an oxidative Heck reaction and their use as starting materials for preparation of Mycobacterium tuberculosis 1-deoxy-D-xylulose-5-phosphate reductoisomerase inhibitors.

Nordqvist A, Björkelid C, Andaloussi M, Jansson AM, Mowbray SL, Karlén A, Larhed M.

J Org Chem. 2011 Nov 4;76(21):8986-98. doi: 10.1021/jo201715x. Epub 2011 Oct 7.


Comminuted fractures of the radial head.

Karlsson MK, Herbertsson P, Nordqvist A, Besjakov J, Josefsson PO, Hasserius R.

Acta Orthop. 2010 Apr;81(2):224-7. doi: 10.3109/17453671003717815. Erratum in: Acta Orthop. 2010 Oct;81(5):647.


Mason type IV fractures of the elbow: a 14- to 46-year follow-up study.

Herbertsson P, Hasserius R, Josefsson PO, Besjakov J, Nyquist F, Nordqvist A, Karlsson MK.

J Bone Joint Surg Br. 2009 Nov;91(11):1499-504. doi: 10.1302/0301-620X.91B11.21957.


Functionalized 3-amino-imidazo[1,2-a]pyridines: a novel class of drug-like Mycobacterium tuberculosis glutamine synthetase inhibitors.

Odell LR, Nilsson MT, Gising J, Lagerlund O, Muthas D, Nordqvist A, Karlén A, Larhed M.

Bioorg Med Chem Lett. 2009 Aug 15;19(16):4790-3. doi: 10.1016/j.bmcl.2009.06.045. Epub 2009 Jun 14.


Long-term outcome of displaced radial neck fractures in adulthood: 16-21 year follow-up of 5 patients treated with radial head excision.

Karlsson MK, Herbertsson P, Nordqvist A, Hasserius R, Besjakov J, Josefsson PO.

Acta Orthop. 2009 Jun;80(3):368-70. doi: 10.3109/17453670902967307.


Physical activity, muscle function, falls and fractures.

Karlsson MK, Nordqvist A, Karlsson C.

Food Nutr Res. 2008;52. doi: 10.3402/fnr.v52i0.1920. Epub 2008 Dec 30.


Physical activity increases bone mass during growth.

Karlsson MK, Nordqvist A, Karlsson C.

Food Nutr Res. 2008;52. doi: 10.3402/fnr.v52i0.1871. Epub 2008 Oct 1.


Sustainability of exercise-induced increases in bone density and skeletal structure.

Karlsson MK, Nordqvist A, Karlsson C.

Food Nutr Res. 2008;52. doi: 10.3402/fnr.v52i0.1872. Epub 2008 Oct 1.


Microwave-enhanced alpha-arylation of a protected glycine in water: evaluation of 3-phenylglycine derivatives as inhibitors of the tuberculosis enzyme, glutamine synthetase.

Lagerlund O, Odell LR, Mowbray SL, Nilsson MT, Krajewski WW, Nordqvist A, Karlén A, Larhed M.

Comb Chem High Throughput Screen. 2007 Nov;10(9):783-9.


Evaluation of the amino acid binding site of Mycobacterium tuberculosis glutamine synthetase for drug discovery.

Nordqvist A, Nilsson MT, Röttger S, Odell LR, Krajewski WW, Evalena Andersson C, Larhed M, Mowbray SL, Karlén A.

Bioorg Med Chem. 2008 May 15;16(10):5501-13. doi: 10.1016/j.bmc.2008.04.015. Epub 2008 Apr 11.


Increased mortality after anterior shoulder dislocation: 255 patients aged 12-40 years followed for 25 years.

Hovelius L, Nilsson JA, Nordqvist A.

Acta Orthop. 2007 Dec;78(6):822-6. doi: 10.1080/17453670710014617.


Links between bacterial production, amino-acid utilization and community composition in productive lakes.

Bertilsson S, Eiler A, Nordqvist A, Jørgensen NO.

ISME J. 2007 Oct;1(6):532-44. Epub 2007 Aug 2.


Quantitative structure-activity relationships of pine weevil antifeedants, a multivariate approach.

Sunnerheim K, Nordqvist A, Nordlander G, Borg-Karlson AK, Unelius CR, Bohman B, Nordenhem H, Hellqvist C, Karlén A.

J Agric Food Chem. 2007 Nov 14;55(23):9365-72. Epub 2007 Oct 10.


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