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Items: 1 to 20 of 188

1.

Structure and mechanisms of ROS generation by NADPH oxidases.

Magnani F, Mattevi A.

Curr Opin Struct Biol. 2019 Apr 30;59:91-97. doi: 10.1016/j.sbi.2019.03.001. [Epub ahead of print] Review.

PMID:
31051297
2.

Histone deacetylases as an epigenetic pillar for the development of hybrid inhibitors in cancer.

Stazi G, Fioravanti R, Mai A, Mattevi A, Valente S.

Curr Opin Chem Biol. 2019 Apr 12;50:89-100. doi: 10.1016/j.cbpa.2019.03.002. [Epub ahead of print] Review.

PMID:
30986654
3.

A Tail-Based Mechanism Drives Nucleosome Demethylation by the LSD2/NPAC Multimeric Complex.

Marabelli C, Marrocco B, Pilotto S, Chittori S, Picaud S, Marchese S, Ciossani G, Forneris F, Filippakopoulos P, Schoehn G, Rhodes D, Subramaniam S, Mattevi A.

Cell Rep. 2019 Apr 9;27(2):387-399.e7. doi: 10.1016/j.celrep.2019.03.061.

4.

Side-Chain Pruning Has Limited Impact on Substrate Preference in a Promiscuous Enzyme.

Fürst MJLJ, Romero E, Gómez Castellanos JR, Fraaije MW, Mattevi A.

ACS Catal. 2018 Dec 7;8(12):11648-11656. doi: 10.1021/acscatal.8b03793. Epub 2018 Oct 30.

5.

Characterization of a thermostable flavin-containing monooxygenase from Nitrincola lacisaponensis (NiFMO).

Lončar N, Fiorentini F, Bailleul G, Savino S, Romero E, Mattevi A, Fraaije MW.

Appl Microbiol Biotechnol. 2019 Feb;103(4):1755-1764. doi: 10.1007/s00253-018-09579-w. Epub 2019 Jan 4.

PMID:
30607493
6.

Development of alkyl glycerone phosphate synthase inhibitors: Structure-activity relationship and effects on ether lipids and epithelial-mesenchymal transition in cancer cells.

Stazi G, Battistelli C, Piano V, Mazzone R, Marrocco B, Marchese S, Louie SM, Zwergel C, Antonini L, Patsilinakos A, Ragno R, Viviano M, Sbardella G, Ciogli A, Fabrizi G, Cirilli R, Strippoli R, Marchetti A, Tripodi M, Nomura DK, Mattevi A, Mai A, Valente S.

Eur J Med Chem. 2019 Feb 1;163:722-735. doi: 10.1016/j.ejmech.2018.11.050. Epub 2018 Nov 28.

PMID:
30576903
7.

Structural and biochemical evaluation of Ceratitis capitata odorant-binding protein 22 affinity for odorants involved in intersex communication.

Falchetto M, Ciossani G, Scolari F, Di Cosimo A, Nenci S, Field LM, Mattevi A, Zhou JJ, Gasperi G, Forneris F.

Insect Mol Biol. 2019 Jun;28(3):431-443. doi: 10.1111/imb.12559. Epub 2019 Jan 17.

PMID:
30548711
8.

The Extreme Structural Plasticity in the CYP153 Subfamily of P450s Directs Development of Designer Hydroxylases.

Fiorentini F, Hatzl AM, Schmidt S, Savino S, Glieder A, Mattevi A.

Biochemistry. 2018 Dec 4;57(48):6701-6714. doi: 10.1021/acs.biochem.8b01052. Epub 2018 Nov 16.

PMID:
30398864
9.

Cryo-EM structures of human STEAP4 reveal mechanism of iron(III) reduction.

Oosterheert W, van Bezouwen LS, Rodenburg RNP, Granneman J, Förster F, Mattevi A, Gros P.

Nat Commun. 2018 Oct 18;9(1):4337. doi: 10.1038/s41467-018-06817-7.

10.

Engineering stability in NADPH oxidases: A common strategy for enzyme production.

Ceccon M, Millana Fananas E, Massari M, Mattevi A, Magnani F.

Mol Membr Biol. 2017 May - Dec;34(3-8):67-76. doi: 10.1080/09687688.2018.1535141. Epub 2019 Jan 10.

PMID:
30307338
11.

Structure-Based Engineering of Phanerochaete chrysosporium Alcohol Oxidase for Enhanced Oxidative Power toward Glycerol.

Nguyen QT, Romero E, Dijkman WP, de Vasconcellos SP, Binda C, Mattevi A, Fraaije MW.

Biochemistry. 2018 Oct 30;57(43):6209-6218. doi: 10.1021/acs.biochem.8b00918. Epub 2018 Oct 16.

12.

Kinetic Resolution of sec-Thiols by Enantioselective Oxidation with Rationally Engineered 5-(Hydroxymethyl)furfural Oxidase.

Pickl M, Swoboda A, Romero E, Winkler CK, Binda C, Mattevi A, Faber K, Fraaije MW.

Angew Chem Int Ed Engl. 2018 Mar 5;57(11):2864-2868. doi: 10.1002/anie.201713189. Epub 2018 Feb 15.

PMID:
29384246
13.

Same Substrate, Many Reactions: Oxygen Activation in Flavoenzymes.

Romero E, Gómez Castellanos JR, Gadda G, Fraaije MW, Mattevi A.

Chem Rev. 2018 Feb 28;118(4):1742-1769. doi: 10.1021/acs.chemrev.7b00650. Epub 2018 Jan 11.

PMID:
29323892
14.

Targeting the CoREST complex with dual histone deacetylase and demethylase inhibitors.

Kalin JH, Wu M, Gomez AV, Song Y, Das J, Hayward D, Adejola N, Wu M, Panova I, Chung HJ, Kim E, Roberts HJ, Roberts JM, Prusevich P, Jeliazkov JR, Roy Burman SS, Fairall L, Milano C, Eroglu A, Proby CM, Dinkova-Kostova AT, Hancock WW, Gray JJ, Bradner JE, Valente S, Mai A, Anders NM, Rudek MA, Hu Y, Ryu B, Schwabe JWR, Mattevi A, Alani RM, Cole PA.

Nat Commun. 2018 Jan 4;9(1):53. doi: 10.1038/s41467-017-02242-4.

15.

Probing the interaction of the p53 C-terminal domain to the histone demethylase LSD1.

Speranzini V, Ciossani G, Marabelli C, Mattevi A.

Arch Biochem Biophys. 2017 Oct 15;632:202-208. doi: 10.1016/j.abb.2017.07.021. Epub 2017 Aug 4.

PMID:
28784588
16.

Baeyer-Villiger Monooxygenase FMO5 as Entry Point in Drug Metabolism.

Fiorentini F, Romero E, Fraaije MW, Faber K, Hall M, Mattevi A.

ACS Chem Biol. 2017 Sep 15;12(9):2379-2387. doi: 10.1021/acschembio.7b00470. Epub 2017 Aug 21.

PMID:
28783300
17.

Two tyrosine residues, Tyr-108 and Tyr-503, are responsible for the deprotonation of phenolic substrates in vanillyl-alcohol oxidase.

Ewing TA, Nguyen QT, Allan RC, Gygli G, Romero E, Binda C, Fraaije MW, Mattevi A, van Berkel WJH.

J Biol Chem. 2017 Sep 1;292(35):14668-14679. doi: 10.1074/jbc.M117.778449. Epub 2017 Jul 17.

18.

3-Hydroxybenzoate 6-Hydroxylase from Rhodococcus jostii RHA1 Contains a Phosphatidylinositol Cofactor.

Montersino S, Te Poele E, Orru R, Westphal AH, Barendregt A, Heck AJR, van der Geize R, Dijkhuizen L, Mattevi A, van Berkel WJH.

Front Microbiol. 2017 Jun 16;8:1110. doi: 10.3389/fmicb.2017.01110. eCollection 2017.

19.

The VAO/PCMH flavoprotein family.

Ewing TA, Fraaije MW, Mattevi A, van Berkel WJH.

Arch Biochem Biophys. 2017 Oct 15;632:104-117. doi: 10.1016/j.abb.2017.06.022. Epub 2017 Jun 30. Review.

PMID:
28669855
20.

Crystal structures and atomic model of NADPH oxidase.

Magnani F, Nenci S, Millana Fananas E, Ceccon M, Romero E, Fraaije MW, Mattevi A.

Proc Natl Acad Sci U S A. 2017 Jun 27;114(26):6764-6769. doi: 10.1073/pnas.1702293114. Epub 2017 Jun 12.

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