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Items: 1 to 20 of 30


Assessing Risk of Future Suicidality in Emergency Department Patients.

Brucker K, Duggan C, Niezer J, Roseberry K, Le-Niculescu H, Niculescu AB, Kline JA.

Acad Emerg Med. 2018 Oct 30. doi: 10.1111/acem.13562. [Epub ahead of print]


Precision medicine for suicidality: from universality to subtypes and personalization.

Niculescu AB, Le-Niculescu H, Levey DF, Phalen PL, Dainton HL, Roseberry K, Niculescu EM, Niezer JO, Williams A, Graham DL, Jones TJ, Venugopal V, Ballew A, Yard M, Gelbart T, Kurian SM, Shekhar A, Schork NJ, Sandusky GE, Salomon DR.

Mol Psychiatry. 2017 Sep;22(9):1250-1273. doi: 10.1038/mp.2017.128. Epub 2017 Aug 15.


Dissecting Suicidality Using a Combined Genomic and Clinical Approach.

Niculescu AB, Le-Niculescu H.

Neuropsychopharmacology. 2017 Jan;42(1):360. doi: 10.1038/npp.2016.228. No abstract available.


Mood, stress and longevity: convergence on ANK3.

Rangaraju S, Levey DF, Nho K, Jain N, Andrews KD, Le-Niculescu H, Salomon DR, Saykin AJ, Petrascheck M, Niculescu AB.

Mol Psychiatry. 2016 Aug;21(8):1037-49. doi: 10.1038/mp.2016.65. Epub 2016 May 24.


Towards understanding and predicting suicidality in women: biomarkers and clinical risk assessment.

Levey DF, Niculescu EM, Le-Niculescu H, Dainton HL, Phalen PL, Ladd TB, Weber H, Belanger E, Graham DL, Khan FN, Vanipenta NP, Stage EC, Ballew A, Yard M, Gelbart T, Shekhar A, Schork NJ, Kurian SM, Sandusky GE, Salomon DR, Niculescu AB.

Mol Psychiatry. 2016 Jun;21(6):768-85. doi: 10.1038/mp.2016.31. Epub 2016 Apr 5.


Understanding and predicting suicidality using a combined genomic and clinical risk assessment approach.

Niculescu AB, Levey DF, Phalen PL, Le-Niculescu H, Dainton HD, Jain N, Belanger E, James A, George S, Weber H, Graham DL, Schweitzer R, Ladd TB, Learman R, Niculescu EM, Vanipenta NP, Khan FN, Mullen J, Shankar G, Cook S, Humbert C, Ballew A, Yard M, Gelbart T, Shekhar A, Schork NJ, Kurian SM, Sandusky GE, Salomon DR.

Mol Psychiatry. 2015 Nov;20(11):1266-85. doi: 10.1038/mp.2015.112. Epub 2015 Aug 18.


Psychiatric blood biomarkers: avoiding jumping to premature negative or positive conclusions.

Niculescu AB, Levey D, Le-Niculescu H, Niculescu E, Kurian SM, Salomon D.

Mol Psychiatry. 2015 Mar;20(3):286-8. doi: 10.1038/mp.2014.180. Epub 2015 Jan 13.


Genetic risk prediction and neurobiological understanding of alcoholism.

Levey DF, Le-Niculescu H, Frank J, Ayalew M, Jain N, Kirlin B, Learman R, Winiger E, Rodd Z, Shekhar A, Schork N, Kiefer F, Wodarz N, Müller-Myhsok B, Dahmen N; GESGA Consortium, Nöthen M, Sherva R, Farrer L, Smith AH, Kranzler HR, Rietschel M, Gelernter J, Niculescu AB.

Transl Psychiatry. 2014 May 20;4:e391. doi: 10.1038/tp.2014.29. Erratum in: Transl Psychiatry. 2014;4:e456. Kiefe, F [corrected to Kiefer, F].


Discovery and validation of blood biomarkers for suicidality.

Le-Niculescu H, Levey DF, Ayalew M, Palmer L, Gavrin LM, Jain N, Winiger E, Bhosrekar S, Shankar G, Radel M, Bellanger E, Duckworth H, Olesek K, Vergo J, Schweitzer R, Yard M, Ballew A, Shekhar A, Sandusky GE, Schork NJ, Kurian SM, Salomon DR, Niculescu AB 3rd.

Mol Psychiatry. 2013 Dec;18(12):1249-64. doi: 10.1038/mp.2013.95. Epub 2013 Aug 20.


Convergent functional genomics of schizophrenia: from comprehensive understanding to genetic risk prediction.

Ayalew M, Le-Niculescu H, Levey DF, Jain N, Changala B, Patel SD, Winiger E, Breier A, Shekhar A, Amdur R, Koller D, Nurnberger JI, Corvin A, Geyer M, Tsuang MT, Salomon D, Schork NJ, Fanous AH, O'Donovan MC, Niculescu AB.

Mol Psychiatry. 2012 Sep;17(9):887-905. doi: 10.1038/mp.2012.37. Epub 2012 May 15.


Convergent functional genomics of anxiety disorders: translational identification of genes, biomarkers, pathways and mechanisms.

Le-Niculescu H, Balaraman Y, Patel SD, Ayalew M, Gupta J, Kuczenski R, Shekhar A, Schork N, Geyer MA, Niculescu AB.

Transl Psychiatry. 2011 May 24;1:e9. doi: 10.1038/tp.2011.9.


Convergent functional genomic studies of ω-3 fatty acids in stress reactivity, bipolar disorder and alcoholism.

Le-Niculescu H, Case NJ, Hulvershorn L, Patel SD, Bowker D, Gupta J, Bell R, Edenberg HJ, Tsuang MT, Kuczenski R, Geyer MA, Rodd ZA, Niculescu AB.

Transl Psychiatry. 2011 Apr 26;1:e4. doi: 10.1038/tp.2011.1.


Convergent integration of animal model and human studies of bipolar disorder (manic-depressive illness).

Le-Niculescu H, Patel SD, Niculescu AB.

Curr Opin Pharmacol. 2010 Oct;10(5):594-600. doi: 10.1016/j.coph.2010.08.008. Review.


Coming to grips with complex disorders: genetic risk prediction in bipolar disorder using panels of genes identified through convergent functional genomics.

Patel SD, Le-Niculescu H, Koller DL, Green SD, Lahiri DK, McMahon FJ, Nurnberger JI Jr, Niculescu AB 3rd.

Am J Med Genet B Neuropsychiatr Genet. 2010 Jun 5;153B(4):850-77. doi: 10.1002/ajmg.b.31087.


The P-value illusion: how to improve (psychiatric) genetic studies.

Niculescu AB, Le-Niculescu H.

Am J Med Genet B Neuropsychiatr Genet. 2010 Jun 5;153B(4):847-9. doi: 10.1002/ajmg.b.31076.


Convergent Functional Genomics: what we have learned and can learn about genes, pathways, and mechanisms.

Niculescu AB, Le-Niculescu H.

Neuropsychopharmacology. 2010 Jan;35(1):355-6. doi: 10.1038/npp.2009.107. No abstract available.


Identification of blood biomarkers for psychosis using convergent functional genomics.

Kurian SM, Le-Niculescu H, Patel SD, Bertram D, Davis J, Dike C, Yehyawi N, Lysaker P, Dustin J, Caligiuri M, Lohr J, Lahiri DK, Nurnberger JI Jr, Faraone SV, Geyer MA, Tsuang MT, Schork NJ, Salomon DR, Niculescu AB.

Mol Psychiatry. 2011 Jan;16(1):37-58. doi: 10.1038/mp.2009.117. Epub 2009 Nov 24.


Evidence for genetic association of RORB with bipolar disorder.

McGrath CL, Glatt SJ, Sklar P, Le-Niculescu H, Kuczenski R, Doyle AE, Biederman J, Mick E, Faraone SV, Niculescu AB, Tsuang MT.

BMC Psychiatry. 2009 Nov 12;9:70. doi: 10.1186/1471-244X-9-70.


Convergent functional genomics of genome-wide association data for bipolar disorder: comprehensive identification of candidate genes, pathways and mechanisms.

Le-Niculescu H, Patel SD, Bhat M, Kuczenski R, Faraone SV, Tsuang MT, McMahon FJ, Schork NJ, Nurnberger JI Jr, Niculescu AB 3rd.

Am J Med Genet B Neuropsychiatr Genet. 2009 Mar 5;150B(2):155-81. doi: 10.1002/ajmg.b.30887.


Identifying blood biomarkers for mood disorders using convergent functional genomics.

Le-Niculescu H, Kurian SM, Yehyawi N, Dike C, Patel SD, Edenberg HJ, Tsuang MT, Salomon DR, Nurnberger JI Jr, Niculescu AB.

Mol Psychiatry. 2009 Feb;14(2):156-74. doi: 10.1038/mp.2008.11. Epub 2008 Feb 26. Erratum in: Mol Psychiatry. 2009 Dec;14(12):1143.


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