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Items: 1 to 20 of 47


Plant-derived secretory component forms secretory IgA with shiga toxin 1-specific dimeric IgA produced by mouse cells and whole plants.

Nakanishi K, Morikane S, Hosokawa N, Kajihara Y, Kurohane K, Niwa Y, Kobayashi H, Imai Y.

Plant Cell Rep. 2019 Feb;38(2):161-172. doi: 10.1007/s00299-018-2358-6. Epub 2018 Nov 30.


Enhancement of mouse contact hypersensitivity appears with a short chain triacylglycerol but not with a long chain one.

Sekiguchi K, Kurohane K, Tsutsumi M, Mochizuki N, Orii A, Nose M, Imai Y.

Toxicology. 2019 Jan 15;412:48-54. doi: 10.1016/j.tox.2018.11.014. Epub 2018 Nov 29.


Skin Sensitization to Fluorescein Isothiocyanate Is Enhanced by Butyl Paraben in a Mouse Model.

Matsuoka T, Endo Y, Kurohane K, Imai Y.

Biol Pharm Bull. 2018 Dec 1;41(12):1853-1858. doi: 10.1248/bpb.b18-00584. Epub 2018 Oct 2.


Adjuvant effect of short chain triacylglycerol tributyrin on a mouse contact hypersensitivity model.

Sekiguchi K, Ogawa E, Kurohane K, Konishi H, Mochizuki N, Manabe K, Imai Y.

Toxicol Lett. 2018 Mar 1;284:56-62. doi: 10.1016/j.toxlet.2017.11.036. Epub 2017 Dec 2.


An Aliphatic Ester Diisopropyl Sebacate Exhibited an Adjuvant Effect on Fluorescein Isothiocyanate-Induced Contact Hypersensitivity Mouse Models.

Kurohane K, Kimura A, Terasawa R, Kobayashi K, Suzuki W, Matsuoka T, Imai Y.

Biol Pharm Bull. 2018 Jan 1;41(1):147-150. doi: 10.1248/bpb.b17-00723. Epub 2017 Oct 27.


Dibutyl Phthalate Rather than Monobutyl Phthalate Facilitates Contact Hypersensitivity to Fluorescein Isothiocyanate in a Mouse Model.

Kurohane K, Sekiguchi K, Ogawa E, Tsutsumi M, Imai Y.

Biol Pharm Bull. 2017 Nov 1;40(11):2010-2013. doi: 10.1248/bpb.b17-00557. Epub 2017 Aug 26.


Protection of Human Colon Cells from Shiga Toxin by Plant-based Recombinant Secretory IgA.

Nakanishi K, Morikane S, Ichikawa S, Kurohane K, Niwa Y, Akimoto Y, Matsubara S, Kawakami H, Kobayashi H, Imai Y.

Sci Rep. 2017 Apr 3;7:45843. doi: 10.1038/srep45843.


Dibutyl Maleate and Dibutyl Fumarate Enhance Contact Sensitization to Fluorescein Isothiocyanate in Mice.

Matsuoka T, Kurohane K, Suzuki W, Ogawa E, Kobayashi K, Imai Y.

Biol Pharm Bull. 2016;39(2):272-7. doi: 10.1248/bpb.b15-00683. Epub 2015 Dec 2.


Lack of Impact of High Dietary Vitamin A on T Helper 2-Dependent Contact Hypersensitivity to Fluorescein Isothiocyanate in Mice.

Kobayashi C, Kurohane K, Imai Y.

Biol Pharm Bull. 2015;38(11):1827-30. doi: 10.1248/bpb.b15-00534. Epub 2015 Aug 21.


Adjuvant Effect of an Alternative Plasticizer, Diisopropyl Adipate, on a Contact Hypersensitivity Mouse Model: Link with Sensory Ion Channel TRPA1 Activation.

Kurohane K, Kimura A, Terasawa R, Sahara Y, Kobayashi K, Suzuki W, Matsuoka T, Watanabe T, Imai Y.

Biol Pharm Bull. 2015;38(7):1054-62. doi: 10.1248/bpb.b15-00199. Epub 2015 May 9.


Recombinant immunoglobulin A specific for influenza A virus hemagglutinin: production, functional analysis, and formation of secretory immunoglobulin A.

Shoji K, Takahashi T, Kurohane K, Iwata K, Matsuoka T, Tsuruta S, Sugino T, Miyake M, Suzuki T, Imai Y.

Viral Immunol. 2015 Apr;28(3):170-8. doi: 10.1089/vim.2014.0098. Epub 2015 Feb 6.


Shiga toxin-induced apoptosis is more efficiently inhibited by dimeric recombinant hybrid-IgG/IgA immunoglobulins than by the parental IgG monoclonal antibodies.

Kurohane K, Nagano K, Nakanishi K, Iwata K, Miyake M, Imai Y.

Virulence. 2014;5(8):819-24. doi: 10.4161/21505594.2014.973804.


Stable expression and characterization of monomeric and dimeric recombinant hybrid-IgG/IgA immunoglobulins specific for Shiga toxin.

Iwata K, Kurohane K, Nakanishi K, Miyake M, Imai Y.

Biol Pharm Bull. 2014;37(9):1510-5. Epub 2014 Jul 1.


Production of hybrid-IgG/IgA plantibodies with neutralizing activity against Shiga toxin 1.

Nakanishi K, Narimatsu S, Ichikawa S, Tobisawa Y, Kurohane K, Niwa Y, Kobayashi H, Imai Y.

PLoS One. 2013 Nov 28;8(11):e80712. doi: 10.1371/journal.pone.0080712. eCollection 2013.


Lack of transient receptor potential melastatin 8 activation by phthalate esters that enhance contact hypersensitivity in mice.

Kurohane K, Sahara Y, Kimura A, Narukawa M, Watanabe T, Daimon T, Imai Y.

Toxicol Lett. 2013 Mar 13;217(3):192-6. doi: 10.1016/j.toxlet.2012.12.025. Epub 2013 Jan 4.


Transient receptor potential ankyrin 1 activation enhances hapten sensitization in a T-helper type 2-driven fluorescein isothiocyanate-induced contact hypersensitivity mouse model.

Shiba T, Tamai T, Sahara Y, Kurohane K, Watanabe T, Imai Y.

Toxicol Appl Pharmacol. 2012 Nov 1;264(3):370-6. doi: 10.1016/j.taap.2012.08.012. Epub 2012 Aug 23.


Establishment of recombinant hybrid-IgG/IgA immunoglobulin specific for Shiga toxin.

Tobisawa Y, Maruyama T, Tanikawa T, Nakanishi K, Kurohane K, Imai Y.

Scand J Immunol. 2011 Dec;74(6):574-84. doi: 10.1111/j.1365-3083.2011.02617.x.


Regulatory effect of cannabinoid receptor agonist on chemokine-induced lymphocyte chemotaxis.

Tanikawa T, Kurohane K, Imai Y.

Biol Pharm Bull. 2011;34(7):1090-3.


Phthalate esters reveal skin-sensitizing activity of phenethyl isothiocyanate in mice.

Matsuda T, Maruyama T, Iizuka H, Kondo A, Tamai T, Kurohane K, Imai Y.

Food Chem Toxicol. 2010 Jun;48(6):1704-8. doi: 10.1016/j.fct.2010.03.049. Epub 2010 Apr 3.


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