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Randomized controlled trials define shape of dose response for Pollinex Quattro Birch allergoid immunotherapy.

Worm M, Higenbottam T, Pfaar O, Mösges R, Aberer W, Gunawardena K, Wessiepe D, Lee D, Kramer MF, Skinner M, Lees B, Zielen S.

Allergy. 2018 Sep;73(9):1812-1822. doi: 10.1111/all.13478. Epub 2018 Jun 19.


Microcrystalline Tyrosine and Aluminum as Adjuvants in Allergen-Specific Immunotherapy Protect from IgE-Mediated Reactivity in Mouse Models and Act Independently of Inflammasome and TLR Signaling.

Leuthard DS, Duda A, Freiberger SN, Weiss S, Dommann I, Fenini G, Contassot E, Kramer MF, Skinner MA, Kündig TM, Heath MD, Johansen P.

J Immunol. 2018 May 1;200(9):3151-3159. doi: 10.4049/jimmunol.1800035. Epub 2018 Mar 28.


Aluminium (Al) speciation in serum and urine after subcutaneous venom immunotherapy with Al as adjuvant.

Michalke B, Kramer MF, Brehler R.

J Trace Elem Med Biol. 2018 Sep;49:178-183. doi: 10.1016/j.jtemb.2018.02.014. Epub 2018 Feb 21.


Microcrystalline Tyrosine (MCT®): A Depot Adjuvant in Licensed Allergy Immunotherapy Offers New Opportunities in Malaria.

Cabral-Miranda G, Heath MD, Gomes AC, Mohsen MO, Montoya-Diaz E, Salman AM, Atcheson E, Skinner MA, Kramer MF, Reyes-Sandoval A, Bachmann MF.

Vaccines (Basel). 2017 Sep 27;5(4). pii: E32. doi: 10.3390/vaccines5040032.


The grass pollen season 2015: a proof of concept multi-approach study in three different European cities.

Kmenta M, Bastl K, Berger U, Kramer MF, Heath MD, Pätsi S, Pessi AM, Saarto A, Werchan B, Werchan M, Zetter R, Bergmann KC.

World Allergy Organ J. 2017 Sep 12;10(1):31. doi: 10.1186/s40413-017-0163-2. eCollection 2017.


Ultra-short-course booster is effective in recurrent grass pollen-induced allergic rhinoconjunctivitis.

Pfaar O, Lang S, Pieper-Fürst U, Astvatsatourov A, Gerich F, Klimek L, Kramer MF, Reydelet Y, Shah-Hosseini K, Mösges R.

Allergy. 2018 Jan;73(1):187-195. doi: 10.1111/all.13240. Epub 2017 Sep 5.


Virus-Like Particle (VLP) Plus Microcrystalline Tyrosine (MCT) Adjuvants Enhance Vaccine Efficacy Improving T and B Cell Immunogenicity and Protection against Plasmodium berghei/vivax.

Cabral-Miranda G, Heath MD, Mohsen MO, Gomes AC, Engeroff P, Flaxman A, Leoratti FMS, El-Turabi A, Reyes-Sandoval A, Skinner MA, Kramer MF, Bachmann MF.

Vaccines (Basel). 2017 May 2;5(2). pii: E10. doi: 10.3390/vaccines5020010.


Clinical use of adjuvants in allergen-immunotherapy.

Klimek L, Schmidt-Weber CB, Kramer MF, Skinner MA, Heath MD.

Expert Rev Clin Immunol. 2017 Jun;13(6):599-610. doi: 10.1080/1744666X.2017.1292133. Epub 2017 Feb 23. Review.


Real-Life Study for the Diagnosis of House Dust Mite Allergy - The Value of Recombinant Allergen-Based IgE Serology.

Becker S, Schlederer T, Kramer MF, Haack M, Vrtala S, Resch Y, Lupinek C, Valenta R, Gröger M.

Int Arch Allergy Immunol. 2016;170(2):132-7. doi: 10.1159/000447694. Epub 2016 Aug 10.


The grass pollen season 2014 in Vienna: A pilot study combining phenology, aerobiology and symptom data.

Kmenta M, Bastl K, Kramer MF, Hewings SJ, Mwange J, Zetter R, Berger U.

Sci Total Environ. 2016 Oct 1;566-567:1614-1620. doi: 10.1016/j.scitotenv.2016.06.059. Epub 2016 Jun 15.


Cytokine patterns in nasal secretion of non-atopic patients distinguish between chronic rhinosinusitis with or without nasal polys.

König K, Klemens C, Haack M, Nicoló MS, Becker S, Kramer MF, Gröger M.

Allergy Asthma Clin Immunol. 2016 Apr 27;12:19. doi: 10.1186/s13223-016-0123-3. eCollection 2016.


Analysis of aluminium in rat following administration of allergen immunotherapy using either aluminium or microcrystalline-tyrosine-based adjuvants.

McDougall SA, Heath MD, Kramer MF, Skinner MA.

Bioanalysis. 2016 Mar;8(6):547-56. doi: 10.4155/bio.16.10. Epub 2016 Feb 26.


In vitro evidence for efficacy in food intolerance for the multispecies probiotic formulation Ecologic® Tolerance (Syngut™).

Besseling-van der Vaart I, Heath MD, Guagnini F, Kramer MF.

Benef Microbes. 2016 Feb;7(1):111-118. doi: 10.3920/BM2015.0051. Epub 2015 Nov 13.


Cytokine profiles in nasal fluid of patients with seasonal or persistent allergic rhinitis.

König K, Klemens C, Eder K, San Nicoló M, Becker S, Kramer MF, Gröger M.

Allergy Asthma Clin Immunol. 2015 Sep 22;11(1):26. doi: 10.1186/s13223-015-0093-x. eCollection 2015.


Non-allergic rhinitis with eosinophilia syndrome is not associated with local production of specific IgE in nasal mucosa.

Becker S, Rasp J, Eder K, Berghaus A, Kramer MF, Gröger M.

Eur Arch Otorhinolaryngol. 2016 Jun;273(6):1469-75. doi: 10.1007/s00405-015-3769-4. Epub 2015 Sep 5.


Aluminium in allergen-specific subcutaneous immunotherapy--a German perspective.

Kramer MF, Heath MD.

Vaccine. 2014 Jul 16;32(33):4140-8. doi: 10.1016/j.vaccine.2014.05.063. Epub 2014 Jun 2.


Probiotics in the treatment of chronic rhinoconjunctivitis and chronic rhinosinusitis.

Kramer MF, Heath MD.

J Allergy (Cairo). 2014;2014:983635. doi: 10.1155/2014/983635. Epub 2014 Apr 28. Review.


[Diagnosis and treatment of acute and chronic rhinosinusitis].

Stelter K, Kramer MF.

MMW Fortschr Med. 2013 Mar 28;155 Spec No 1(1):49-53; quiz 54. Review. German. No abstract available.


Correlation of three variables describing nasal patency (HD, MCA, NOSE score) in healthy subjects.

Braun T, Rich M, Kramer MF.

Braz J Otorhinolaryngol. 2013 May-Jun;79(3):354-8. doi: 10.5935/1808-8694.20130062. English, Portuguese.


[Allergic rhinitis: burden of disease].

Kramer MF.

MMW Fortschr Med. 2013 Mar 21;155(5):57-60; quiz 61-2. Review. German. No abstract available.


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