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Items: 19

1.

Identification of Der p 23, a peritrophin-like protein, as a new major Dermatophagoides pteronyssinus allergen associated with the peritrophic matrix of mite fecal pellets.

Weghofer M, Grote M, Resch Y, Casset A, Kneidinger M, Kopec J, Thomas WR, Fernández-Caldas E, Kabesch M, Ferrara R, Mari A, Purohit A, Pauli G, Horak F, Keller W, Valent P, Valenta R, Vrtala S.

J Immunol. 2013 Apr 1;190(7):3059-67. doi: 10.4049/jimmunol.1202288. Epub 2013 Mar 4.

2.

Glucocorticosteroids rescue basophils from dasatinib-augmented immunoglobulin E-mediated histamine release.

Herrmann H, Blatt K, Ghanim V, Kneidinger M, Marth K, Valenta R, Valent P.

Int Arch Allergy Immunol. 2012;159(1):15-22. doi: 10.1159/000335146. Epub 2012 Apr 27.

PMID:
22555087
3.

Carrier-bound nonallergenic Der p 2 peptides induce IgG antibodies blocking allergen-induced basophil activation in allergic patients.

Chen KW, Focke-Tejkl M, Blatt K, Kneidinger M, Gieras A, Dall'Antonia F, Faé I, Fischer G, Keller W, Valent P, Valenta R, Vrtala S.

Allergy. 2012 May;67(5):609-21. doi: 10.1111/j.1398-9995.2012.02794.x. Epub 2012 Feb 17.

4.

The Hsp32 inhibitors SMA-ZnPP and PEG-ZnPP exert major growth-inhibitory effects on D34+/CD38+ and CD34+/CD38- AML progenitor cells.

Herrmann H, Kneidinger M, Cerny-Reiterer S, Rülicke T, Willmann M, Gleixner KV, Blatt K, Hörmann G, Peter B, Samorapoompichit P, Pickl W, Bharate GY, Mayerhofer M, Sperr WR, Maeda H, Valent P.

Curr Cancer Drug Targets. 2012 Jan;12(1):51-63.

PMID:
22165967
5.

Midostaurin (PKC412) inhibits immunoglobulin E-dependent activation and mediator release in human blood basophils and mast cells.

Krauth MT, Mirkina I, Herrmann H, Baumgartner C, Kneidinger M, Valent P.

Clin Exp Allergy. 2009 Nov;39(11):1711-20. doi: 10.1111/j.1365-2222.2009.03353.x.

PMID:
19860818
6.

Identification of proapoptotic Bim as a tumor suppressor in neoplastic mast cells: role of KIT D816V and effects of various targeted drugs.

Aichberger KJ, Gleixner KV, Mirkina I, Cerny-Reiterer S, Peter B, Ferenc V, Kneidinger M, Baumgartner C, Mayerhofer M, Gruze A, Pickl WF, Sillaber C, Valent P.

Blood. 2009 Dec 17;114(26):5342-51. doi: 10.1182/blood-2008-08-175190. Epub 2009 Oct 22.

7.

The protein tyrosine kinase Tec regulates mast cell function.

Schmidt U, Abramova A, Boucheron N, Eckelhart E, Schebesta A, Bilic I, Kneidinger M, Unger B, Hammer M, Sibilia M, Valent P, Ellmeier W.

Eur J Immunol. 2009 Nov;39(11):3228-38. doi: 10.1002/eji.200838839.

8.

A combination vaccine for allergy and rhinovirus infections based on rhinovirus-derived surface protein VP1 and a nonallergenic peptide of the major timothy grass pollen allergen Phl p 1.

Edlmayr J, Niespodziana K, Linhart B, Focke-Tejkl M, Westritschnig K, Scheiblhofer S, Stoecklinger A, Kneidinger M, Valent P, Campana R, Thalhamer J, Popow-Kraupp T, Valenta R.

J Immunol. 2009 May 15;182(10):6298-306. doi: 10.4049/jimmunol.0713622.

9.

Trimolecular complex formation of IgE, Fc epsilon RI, and a recombinant nonanaphylactic single-chain antibody fragment with high affinity for IgE.

Lupinek C, Roux KH, Laffer S, Rauter I, Reginald K, Kneidinger M, Blatt K, Ball T, Pree I, Jahn-Schmid B, Allam JP, Novak N, Drescher A, Kricek F, Valent P, Englund H, Valenta R.

J Immunol. 2009 Apr 15;182(8):4817-29. doi: 10.4049/jimmunol.0800726.

10.

CD203c is overexpressed on neoplastic mast cells in systemic mastocytosis and is upregulated upon IgE receptor cross-linking.

Hauswirth AW, Escribano L, Prados A, Nuñez R, Mirkina I, Kneidinger M, Florian S, Sonneck K, Vales A, Schernthaner GH, Sanchez-Muñoz L, Sperr WR, Bühring HJ, Orfao A, Valent P.

Int J Immunopathol Pharmacol. 2008 Oct-Dec;21(4):797-806.

PMID:
19144265
11.

Cigarette smoke facilitates allergen penetration across respiratory epithelium.

Gangl K, Reininger R, Bernhard D, Campana R, Pree I, Reisinger J, Kneidinger M, Kundi M, Dolznig H, Thurnher D, Valent P, Chen KW, Vrtala S, Spitzauer S, Valenta R, Niederberger V.

Allergy. 2009 Mar;64(3):398-405. doi: 10.1111/j.1398-9995.2008.01861.x. Epub 2008 Dec 16.

PMID:
19120070
12.

Targeting of heat-shock protein 32/heme oxygenase-1 in canine mastocytoma cells is associated with reduced growth and induction of apoptosis.

Hadzijusufovic E, Rebuzzi L, Gleixner KV, Ferenc V, Peter B, Kondo R, Gruze A, Kneidinger M, Krauth MT, Mayerhofer M, Samorapoompichit P, Greish K, Iyer AK, Pickl WF, Maeda H, Willmann M, Valent P.

Exp Hematol. 2008 Nov;36(11):1461-70. doi: 10.1016/j.exphem.2008.06.002. Epub 2008 Aug 23.

PMID:
18723263
13.

A hypoallergenic hybrid molecule with increased immunogenicity consisting of derivatives of the major grass pollen allergens, Phl p 2 and Phl p 6.

Linhart B, Mothes-Luksch N, Vrtala S, Kneidinger M, Valent P, Valenta R.

Biol Chem. 2008 Jul;389(7):925-33. doi: 10.1515/BC.2008.105.

PMID:
18627317
14.

Characterization of Der p 21, a new important allergen derived from the gut of house dust mites.

Weghofer M, Dall'Antonia Y, Grote M, Stöcklinger A, Kneidinger M, Balic N, Krauth MT, Fernández-Caldas E, Thomas WR, van Hage M, Vieths S, Spitzauer S, Horak F, Svergun DI, Konarev PV, Valent P, Thalhamer J, Keller W, Valenta R, Vrtala S.

Allergy. 2008 Jun;63(6):758-67. doi: 10.1111/j.1398-9995.2008.01647.x.

PMID:
18445190
15.

Immunohistochemical assessment of CD25 is equally sensitive and diagnostic in mastocytosis compared to flow cytometry.

Baumgartner C, Sonneck K, Krauth MT, Kneidinger M, Födinger M, Hauswirth AW, Müllauer L, Valent P.

Eur J Clin Invest. 2008 May;38(5):326-35. doi: 10.1111/j.1365-2362.2008.01942.x. Epub 2008 Mar 20.

PMID:
18363719
16.

A high-affinity monoclonal anti-IgE antibody for depletion of IgE and IgE-bearing cells.

Laffer S, Lupinek C, Rauter I, Kneidinger M, Drescher A, Jordan JH, Krauth MT, Valent P, Kricek F, Spitzauer S, Englund H, Valenta R.

Allergy. 2008 Jun;63(6):695-702. doi: 10.1111/j.1398-9995.2008.01664.x. Epub 2008 Mar 5.

PMID:
18325077
17.

The effects of dasatinib on IgE receptor-dependent activation and histamine release in human basophils.

Kneidinger M, Schmidt U, Rix U, Gleixner KV, Vales A, Baumgartner C, Lupinek C, Weghofer M, Bennett KL, Herrmann H, Schebesta A, Thomas WR, Vrtala S, Valenta R, Lee FY, Ellmeier W, Superti-Furga G, Valent P.

Blood. 2008 Mar 15;111(6):3097-107. doi: 10.1182/blood-2007-08-104372. Epub 2008 Jan 7.

18.

The Btk tyrosine kinase is a major target of the Bcr-Abl inhibitor dasatinib.

Hantschel O, Rix U, Schmidt U, Bürckstümmer T, Kneidinger M, Schütze G, Colinge J, Bennett KL, Ellmeier W, Valent P, Superti-Furga G.

Proc Natl Acad Sci U S A. 2007 Aug 14;104(33):13283-8. Epub 2007 Aug 7.

19.

Synergistic antiproliferative effects of KIT tyrosine kinase inhibitors on neoplastic canine mast cells.

Gleixner KV, Rebuzzi L, Mayerhofer M, Gruze A, Hadzijusufovic E, Sonneck K, Vales A, Kneidinger M, Samorapoompichit P, Thaiwong T, Pickl WF, Yuzbasiyan-Gurkan V, Sillaber C, Willmann M, Valent P.

Exp Hematol. 2007 Oct;35(10):1510-21. Epub 2007 Aug 2.

PMID:
17681669

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