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Usage, biological activity, and safety of selected botanical dietary supplements consumed in the United States.

Benatrehina PA, Pan L, Naman CB, Li J, Kinghorn AD.

J Tradit Complement Med. 2018 Mar 2;8(2):267-277. doi: 10.1016/j.jtcme.2018.01.006. eCollection 2018 Apr. Review.


Synthesis and antiproliferative activity of derivatives of the phyllanthusmin class of arylnaphthalene lignan lactones.

Woodard JL, Huntsman AC, Patel PA, Chai HB, Kanagasabai R, Karmahapatra S, Young AN, Ren Y, Cole MS, Herrera D, Yalowich JC, Kinghorn AD, Burdette JE, Fuchs JR.

Bioorg Med Chem. 2018 May 15;26(9):2354-2364. doi: 10.1016/j.bmc.2018.03.033. Epub 2018 Mar 23.


Changes for Volume 81.

Kinghorn AD.

J Nat Prod. 2018 Jan 26;81(1):1. doi: 10.1021/acs.jnatprod.7b01078. No abstract available.


Crystal Structures and Human Leukemia Cell Apoptosis Inducible Activities of Parthenolide Analogues Isolated from Piptocoma rufescens.

Ren Y, Gallucci JC, Li X, Chen L, Yu J, Kinghorn AD.

J Nat Prod. 2018 Mar 23;81(3):554-561. doi: 10.1021/acs.jnatprod.7b01079. Epub 2018 Jan 19.


Revisiting the linkage between ethnomedical use and development of new medicines: A novel plant collection strategy towards the discovery of anticancer agents.

Henkin JM, Sydara K, Xayvue M, Souliya O, Kinghorn AD, Burdette JE, Chen WL, Elkington BG, Soejarto DD.

J Med Plant Res. 2017 Oct;11(40):621-634. Epub 2017 Oct 25.


Bioassay-Guided Isolation of Antioxidant and Cytoprotective Constituents from a Maqui Berry (Aristotelia chilensis) Dietary Supplement Ingredient As Markers for Qualitative and Quantitative Analysis.

Li J, Yuan C, Pan L, Benatrehina PA, Chai H, Keller WJ, Naman CB, Kinghorn AD.

J Agric Food Chem. 2017 Oct 4;65(39):8634-8642. doi: 10.1021/acs.jafc.7b03261. Epub 2017 Sep 26.


Pentalinonsterol, a Constituent of Pentalinon andrieuxii, Possesses Potent Immunomodulatory Activity and Primes T Cell Immune Responses.

Oghumu S, Varikuti S, Saljoughian N, Terrazas C, Huntsman AC, Parinandi NL, Fuchs JR, Kinghorn AD, Satoskar AR.

J Nat Prod. 2017 Sep 22;80(9):2515-2523. doi: 10.1021/acs.jnatprod.7b00445. Epub 2017 Sep 6.


Overexpression of eIF4F components in meningiomas and suppression of meningioma cell growth by inhibiting translation initiation.

Oblinger JL, Burns SS, Huang J, Pan L, Ren Y, Shen R, Kinghorn AD, Welling DB, Chang LS.

Exp Neurol. 2018 Jan;299(Pt B):299-307. doi: 10.1016/j.expneurol.2017.06.015. Epub 2017 Jun 10.


An Intramolecular CAr-H•••O=C Hydrogen Bond and the Configuration of Rotenoids.

Ren Y, Gallucci JC, Kinghorn AD.

Planta Med. 2017 Oct;83(14-15):1194-1199. doi: 10.1055/s-0043-108910. Epub 2017 Apr 20.


(+)-Strebloside-Induced Cytotoxicity in Ovarian Cancer Cells Is Mediated through Cardiac Glycoside Signaling Networks.

Chen WL, Ren Y, Ren J, Erxleben C, Johnson ME, Gentile S, Kinghorn AD, Swanson SM, Burdette JE.

J Nat Prod. 2017 Mar 24;80(3):659-669. doi: 10.1021/acs.jnatprod.6b01150. Epub 2017 Feb 24.


Changes for Volume 80.

Kinghorn AD.

J Nat Prod. 2017 Jan 27;80(1):1. doi: 10.1021/acs.jnatprod.6b01155. No abstract available.


Cardiac Glycoside Constituents of Streblus asper with Potential Antineoplastic Activity.

Ren Y, Chen WL, Lantvit DD, Sass EJ, Shriwas P, Ninh TN, Chai HB, Zhang X, Soejarto DD, Chen X, Lucas DM, Swanson SM, Burdette JE, Kinghorn AD.

J Nat Prod. 2017 Mar 24;80(3):648-658. doi: 10.1021/acs.jnatprod.6b00924. Epub 2016 Dec 16.


Discovery of Anticancer Agents of Diverse Natural Origin.

Kinghorn AD, DE Blanco EJ, Lucas DM, Rakotondraibe HL, Orjala J, Soejarto DD, Oberlies NH, Pearce CJ, Wani MC, Stockwell BR, Burdette JE, Swanson SM, Fuchs JR, Phelps MA, Xu L, Zhang X, Shen YY.

Anticancer Res. 2016 Nov;36(11):5623-5637. Review.


Discovery of anabaenopeptin 679 from freshwater algal bloom material: Insights into the structure-activity relationship of anabaenopeptin protease inhibitors.

Harms H, Kurita KL, Pan L, Wahome PG, He H, Kinghorn AD, Carter GT, Linington RG.

Bioorg Med Chem Lett. 2016 Oct 15;26(20):4960-4965. doi: 10.1016/j.bmcl.2016.09.008. Epub 2016 Sep 6.


A Novel Sterol Isolated from a Plant Used by Mayan Traditional Healers Is Effective in Treatment of Visceral Leishmaniasis Caused by Leishmania donovani.

Gupta G, Peine KJ, Abdelhamid D, Snider H, Shelton AB, Rao L, Kotha SR, Huntsman AC, Varikuti S, Oghumu S, Naman CB, Pan L, Parinandi NL, Papenfuss TL, Kinghorn AD, Bachelder EM, Ainslie KM, Fuchs JR, Satoskar AR.

ACS Infect Dis. 2015 Oct 9;1(10):497-506. doi: 10.1021/acsinfecdis.5b00081. Epub 2015 Sep 21.


Isolation of Bioactive Rotenoids and Isoflavonoids from the Fruits of Millettia caerulea.

Ren Y, Benatrehina PA, Muñoz Acuña U, Yuan C, Chai HB, Ninh TN, Carcache de Blanco EJ, Soejarto DD, Kinghorn AD.

Planta Med. 2016 Jul;82(11-12):1096-104. doi: 10.1055/s-0042-108059. Epub 2016 Jun 9.


Development of Anticancer Agents from Plant-Derived Sesquiterpene Lactones.

Ren Y, Yu J, Kinghorn AD.

Curr Med Chem. 2016;23(23):2397-420. Review.


Cyclopenta[b]benzofuran and Secodammarane Derivatives from the Stems of Aglaia stellatopilosa.

Othman N, Pan L, Mejin M, Voong JC, Chai HB, Pannell CM, Kinghorn AD, Yeo TC.

J Nat Prod. 2016 Apr 22;79(4):784-91. doi: 10.1021/acs.jnatprod.5b00810. Epub 2016 Mar 14.


Components of the eIF4F complex are potential therapeutic targets for malignant peripheral nerve sheath tumors and vestibular schwannomas.

Oblinger JL, Burns SS, Akhmametyeva EM, Huang J, Pan L, Ren Y, Shen R, Miles-Markley B, Moberly AC, Kinghorn AD, Welling DB, Chang LS.

Neuro Oncol. 2016 Sep;18(9):1265-77. doi: 10.1093/neuonc/now032. Epub 2016 Mar 6.


Antileishmanial and Cytotoxic Activity of Some Highly Oxidized Abietane Diterpenoids from the Bald Cypress, Taxodium distichum.

Naman CB, Gromovsky AD, Vela CM, Fletcher JN, Gupta G, Varikuti S, Zhu X, Zywot EM, Chai H, Werbovetz KA, Satoskar AR, Kinghorn AD.

J Nat Prod. 2016 Mar 25;79(3):598-606. doi: 10.1021/acs.jnatprod.5b01131. Epub 2016 Feb 23.

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