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Effect of apolipoprotein E ε4 allele on the progression of cognitive decline in the early stage of Alzheimer's disease.

Suzuki K, Hirakawa A, Ihara R, Iwata A, Ishii K, Ikeuchi T, Sun CK, Donohue M, Iwatsubo T; Alzheimer's Disease Neuroimaging Initiative, Japanese Alzheimer's Disease Neuroimaging Initiative.

Alzheimers Dement (N Y). 2020 Mar 20;6(1):e12007. doi: 10.1002/trc2.12007. eCollection 2020.


Roles of Collagen XXV and Its Putative Receptors PTPσ/δ in Intramuscular Motor Innervation and Congenital Cranial Dysinnervation Disorder.

Munezane H, Oizumi H, Wakabayashi T, Nishio S, Hirasawa T, Sato T, Harada A, Yoshida T, Eguchi T, Yamanashi Y, Hashimoto T, Iwatsubo T.

Cell Rep. 2019 Dec 24;29(13):4362-4376.e6. doi: 10.1016/j.celrep.2019.11.112.


Seeding Activity-Based Detection Uncovers the Different Release Mechanisms of Seed-Competent Tau Versus Inert Tau via Lysosomal Exocytosis.

Tanaka Y, Yamada K, Satake K, Nishida I, Heuberger M, Kuwahara T, Iwatsubo T.

Front Neurosci. 2019 Nov 21;13:1258. doi: 10.3389/fnins.2019.01258. eCollection 2019.


High incidence of head and neck cancers after endoscopic resection for esophageal cancer in younger patients.

Maekawa A, Ishihara R, Iwatsubo T, Nakagawa K, Ohmori M, Iwagami H, Matsuno K, Inoue S, Arao M, Nakahira H, Matsuura N, Schichijo S, Kanesaka T, Yamamoto S, Takeuchi Y, Higashino K, Uedo N, Fujii T, Morishima T, Miyashiro I.

J Gastroenterol. 2020 Apr;55(4):401-407. doi: 10.1007/s00535-019-01653-y. Epub 2019 Dec 7.


Evaluation of drug-drug interactions in drug metabolism: Differences and harmonization in guidance/guidelines.

Iwatsubo T.

Drug Metab Pharmacokinet. 2020 Feb;35(1):71-75. doi: 10.1016/j.dmpk.2019.10.006. Epub 2019 Oct 22. Review.


Evaluation of PiB visual interpretation with CSF Aβ and longitudinal SUVR in J-ADNI study.

Okada Y, Kato T, Iwata K, Kimura Y, Nakamura A, Hattori H, Toyama H, Ishii K, Ishii K, Senda M, Ito K, Iwatsubo T; Japanese Alzheimer’s Disease Neuroimaging Initiative.

Ann Nucl Med. 2020 Feb;34(2):108-118. doi: 10.1007/s12149-019-01420-2. Epub 2019 Nov 20.


Author Correction: Collagen XXV promotes myoblast fusion during myogenic differentiation and muscle formation.

Gonçalves TJM, Boutillon F, Lefebvre S, Goffin V, Iwatsubo T, Wakabayashi T, Oury F, Armand AS.

Sci Rep. 2019 Nov 21;9(1):17519. doi: 10.1038/s41598-019-53896-7.


Endoscopic full-thickness resection of gastric gastrointestinal stromal tumor: a Japanese case series.

Shichijo S, Uedo N, Yanagimoto Y, Yamamoto K, Kono M, Fukuda H, Shimamoto Y, Nakagawa K, Ohmori M, Arao M, Iwatsubo T, Iwagami H, Inoue S, Matsuno K, Matsuura N, Nakahira H, Maekawa A, Kanesaka T, Takeuchi Y, Higashino K, Ohmori T, Ishihara R.

Ann Gastroenterol. 2019 Nov-Dec;32(6):593-599. doi: 10.20524/aog.2019.0413. Epub 2019 Sep 23.


Endoscopic appearance of esophageal xanthoma.

Hamada K, Uedo N, Kubo C, Tomita Y, Ishihara R, Yamasaki Y, Omori M, Arao M, Suzuki S, Iwatsubo T, Kato M, Tonai Y, Shichijo S, Matsuura N, Nakahira H, Kanesaka T, Yamamoto S, Akasaka T, Hanaoka N, Takeuchi Y, Higashino K, Okada H, Iishi H.

Endosc Int Open. 2019 Oct;7(10):E1214-E1220. doi: 10.1055/a-0966-8544. Epub 2019 Oct 1.


Calcium Carbonate Skeletal Material Is Synthesized via Phase Transition of the Calcium Carbonate Cartilaginous Material.

Iwatsubo T, Kishi R, Yamaguchi T.

ACS Omega. 2019 Sep 4;4(12):14820-14830. doi: 10.1021/acsomega.9b01420. eCollection 2019 Sep 17.


Feasibility of underwater endoscopic mucosal resection and management of residues for superficial non-ampullary duodenal epithelial neoplasms.

Iwagami H, Takeuchi Y, Yamasaki Y, Nakagawa K, Ohmori M, Matsuno K, Inoue S, Iwatsubo T, Nakahira H, Matsuura N, Shichijo S, Maekawa A, Kanesaka T, Higashino K, Uedo N, Ishihara R.

Dig Endosc. 2019 Sep 24. doi: 10.1111/den.13541. [Epub ahead of print]


Identification of prognostic factors to predict cognitive decline of patients with early Alzheimer's disease in the Japanese Alzheimer's Disease Neuroimaging Initiative study.

Yagi T, Kanekiyo M, Ito J, Ihara R, Suzuki K, Iwata A, Iwatsubo T, Aoshima K; Alzheimer's Disease Neuroimaging Initiative; Japanese Alzheimer's Disease Neuroimaging Initiative.

Alzheimers Dement (N Y). 2019 Aug 7;5:364-373. doi: 10.1016/j.trci.2019.06.004. eCollection 2019.


Visualizing modules of coordinated structural brain atrophy during the course of conversion to Alzheimer's disease by applying methodology from gene co-expression analysis.

Sato K, Mano T, Matsuda H, Senda M, Ihara R, Suzuki K, Arai H, Ishii K, Ito K, Ikeuchi T, Kuwano R, Toda T, Iwatsubo T, Iwata A; Japanese Alzheimer's Disease Neuroimaging Initiative.

Neuroimage Clin. 2019;24:101957. doi: 10.1016/j.nicl.2019.101957. Epub 2019 Jul 25.


Calcium-responsive transactivator (CREST) toxicity is rescued by loss of PBP1/ATXN2 function in a novel yeast proteinopathy model and in transgenic flies.

Park S, Park SK, Watanabe N, Hashimoto T, Iwatsubo T, Shelkovnikova TA, Liebman SW.

PLoS Genet. 2019 Aug 7;15(8):e1008308. doi: 10.1371/journal.pgen.1008308. eCollection 2019 Aug.


Does cold snare polypectomy completely resect the mucosal layer? A prospective single-center observational trial.

Shichijo S, Takeuchi Y, Kitamura M, Kono M, Shimamoto Y, Fukuda H, Nakagawa K, Ohmori M, Arao M, Iwatsubo T, Iwagami H, Matsuno K, Inoue S, Matsuura N, Nakahira H, Maekawa A, Kanesaka T, Higashino K, Uedo N, Fukui K, Ito Y, Nakatsuka SI, Ishihara R.

J Gastroenterol Hepatol. 2020 Feb;35(2):241-248. doi: 10.1111/jgh.14824. Epub 2019 Sep 10.


Differentiation between duodenal neoplasms and non-neoplasms using magnifying narrow-band imaging - Do we still need biopsies for duodenal lesions?

Yamasaki Y, Takeuchi Y, Kanesaka T, Kanzaki H, Kato M, Ohmori M, Tonai Y, Hamada K, Matsuura N, Iwatsubo T, Akasaka T, Hanaoka N, Higashino K, Uedo N, Ishihara R, Okada H, Iishi H.

Dig Endosc. 2020 Jan;32(1):84-95. doi: 10.1111/den.13485. Epub 2019 Aug 20.


Characterization of the unique In Vitro effects of unsaturated fatty acids on the formation of amyloid β fibrils.

Eto M, Hashimoto T, Shimizu T, Iwatsubo T.

PLoS One. 2019 Jul 10;14(7):e0219465. doi: 10.1371/journal.pone.0219465. eCollection 2019.


Combination Therapy for Alzheimer's Disease: Perspectives of the EU/US CTAD Task Force.

Gauthier S, Alam J, Fillit H, Iwatsubo T, Liu-Seifert H, Sabbagh M, Salloway S, Sampaio C, Sims JR, Sperling B, Sperling R, Welsh-Bohmer KA, Touchon J, Vellas B, Aisen P.

J Prev Alzheimers Dis. 2019;6(3):164-168. doi: 10.14283/jpad.2019.12.


Comparison of Underwater vs Conventional Endoscopic Mucosal Resection of Intermediate-Size Colorectal Polyps.

Yamashina T, Uedo N, Akasaka T, Iwatsubo T, Nakatani Y, Akamatsu T, Kawamura T, Takeuchi Y, Fujii S, Kusaka T, Shimokawa T.

Gastroenterology. 2019 Aug;157(2):451-461.e2. doi: 10.1053/j.gastro.2019.04.005. Epub 2019 Apr 11.


Differential effects of diet- and genetically-induced brain insulin resistance on amyloid pathology in a mouse model of Alzheimer's disease.

Wakabayashi T, Yamaguchi K, Matsui K, Sano T, Kubota T, Hashimoto T, Mano A, Yamada K, Matsuo Y, Kubota N, Kadowaki T, Iwatsubo T.

Mol Neurodegener. 2019 Apr 12;14(1):15. doi: 10.1186/s13024-019-0315-7.

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