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Items: 1 to 20 of 66

1.

Thioredoxin-Interacting Protein (TXNIP) Associated NLRP3 Inflammasome Activation in Human Alzheimer's Disease Brain.

Li L, Ismael S, Nasoohi S, Sakata K, Liao FF, McDonald MP, Ishrat T.

J Alzheimers Dis. 2019 Feb 6. doi: 10.3233/JAD-180814. [Epub ahead of print]

PMID:
30741672
2.

Metabolic Syndrome, Brain Insulin Resistance, and Alzheimer's Disease: Thioredoxin Interacting Protein (TXNIP) and Inflammasome as Core Amplifiers.

Nasoohi S, Parveen K, Ishrat T.

J Alzheimers Dis. 2018;66(3):857-885. doi: 10.3233/JAD-180735.

PMID:
30372683
3.

Angiotensin receptor (AT2R) agonist C21 prevents cognitive decline after permanent stroke in aged animals-A randomized double- blind pre-clinical study.

Ahmed HA, Ishrat T, Pillai B, Bunting KM, Vazdarjanova A, Waller JL, Ergul A, Fagan SC.

Behav Brain Res. 2019 Feb 1;359:560-569. doi: 10.1016/j.bbr.2018.10.010. Epub 2018 Oct 5.

4.

RAS modulation prevents progressive cognitive impairment after experimental stroke: a randomized, blinded preclinical trial.

Ahmed HA, Ishrat T, Pillai B, Fouda AY, Sayed MA, Eldahshan W, Waller JL, Ergul A, Fagan SC.

J Neuroinflammation. 2018 Aug 13;15(1):229. doi: 10.1186/s12974-018-1262-x.

5.

Silencing VEGF-B Diminishes the Neuroprotective Effect of Candesartan Treatment After Experimental Focal Cerebral Ischemia.

Ishrat T, Soliman S, Eldahshan W, Pillai B, Ergul A, Fagan SC.

Neurochem Res. 2018 Oct;43(10):1869-1878. doi: 10.1007/s11064-018-2604-x. Epub 2018 Aug 7.

PMID:
30088238
6.

Inhibition of the NLRP3-inflammasome as a potential approach for neuroprotection after stroke.

Ismael S, Zhao L, Nasoohi S, Ishrat T.

Sci Rep. 2018 Apr 13;8(1):5971. doi: 10.1038/s41598-018-24350-x.

7.

Dose-response, therapeutic time-window and tPA-combinatorial efficacy of compound 21: A randomized, blinded preclinical trial in a rat model of thromboembolic stroke.

Ishrat T, Fouda AY, Pillai B, Eldahshan W, Ahmed H, Waller JL, Ergul A, Fagan SC.

J Cereb Blood Flow Metab. 2018 Mar 14:271678X18764773. doi: 10.1177/0271678X18764773. [Epub ahead of print]

PMID:
29537907
8.

Thioredoxin-Interacting Protein (TXNIP) in Cerebrovascular and Neurodegenerative Diseases: Regulation and Implication.

Nasoohi S, Ismael S, Ishrat T.

Mol Neurobiol. 2018 Oct;55(10):7900-7920. doi: 10.1007/s12035-018-0917-z. Epub 2018 Feb 27. Review.

PMID:
29488135
9.

MCC950, the Selective Inhibitor of Nucleotide Oligomerization Domain-Like Receptor Protein-3 Inflammasome, Protects Mice against Traumatic Brain Injury.

Ismael S, Nasoohi S, Ishrat T.

J Neurotrauma. 2018 Jun 1;35(11):1294-1303. doi: 10.1089/neu.2017.5344. Epub 2018 Apr 2.

PMID:
29295651
10.

Role of angiotensin system modulation on progression of cognitive impairment and brain MRI changes in aged hypertensive animals - A randomized double- blind pre-clinical study.

Ahmed HA, Ishrat T, Pillai B, Bunting KM, Patel A, Vazdarjanova A, Waller JL, Arbab AS, Ergul A, Fagan SC.

Behav Brain Res. 2018 Jul 2;346:29-40. doi: 10.1016/j.bbr.2017.12.007. Epub 2017 Dec 8.

PMID:
29229547
11.

Mechanisms of acute neurovascular protection with AT1 blockade after stroke: Effect of prestroke hypertension.

Alhusban A, Kozak A, Pillai B, Ahmed H, Sayed MA, Johnson MH, Ishrat T, Ergul A, Fagan SC.

PLoS One. 2017 Jun 22;12(6):e0178867. doi: 10.1371/journal.pone.0178867. eCollection 2017.

12.

MyD88 contributes to neuroinflammatory responses induced by cerebral ischemia/reperfusion in mice.

Ye X, Kong D, Wang J, Ishrat T, Shi H, Ding X, Cui G, Hua F.

Biochem Biophys Res Commun. 2016 Nov 4;480(1):69-74. doi: 10.1016/j.bbrc.2016.10.007. Epub 2016 Oct 4.

13.

Progesterone improves long-term functional and histological outcomes after permanent stroke in older rats.

Wali B, Ishrat T, Stein DG, Sayeed I.

Behav Brain Res. 2016 May 15;305:46-56. doi: 10.1016/j.bbr.2016.02.024. Epub 2016 Feb 26.

14.

Brain-Derived Neurotrophic Factor Knockdown Blocks the Angiogenic and Protective Effects of Angiotensin Modulation After Experimental Stroke.

Fouda AY, Alhusban A, Ishrat T, Pillai B, Eldahshan W, Waller JL, Ergul A, Fagan SC.

Mol Neurobiol. 2017 Jan;54(1):661-670. doi: 10.1007/s12035-015-9675-3. Epub 2016 Jan 12.

15.

Sequential Therapy with Minocycline and Candesartan Improves Long-Term Recovery After Experimental Stroke.

Soliman S, Ishrat T, Fouda AY, Patel A, Pillai B, Fagan SC.

Transl Stroke Res. 2015 Aug;6(4):309-22. doi: 10.1007/s12975-015-0408-8. Epub 2015 May 26.

16.

Erratum to: Thioredoxin-interacting protein: a novel target for neuroprotection in experimental thromboembolic stroke in mice.

Ishrat T, Mohamed IN, Pillai B, Soliman S, Fouda AY, Ergul A, El-Remessy AB, Fagan SC.

Mol Neurobiol. 2015 Apr;51(2):779-80. doi: 10.1007/s12035-014-9025-x. No abstract available.

PMID:
25502293
17.

Sesamin attenuates neurotoxicity in mouse model of ischemic brain stroke.

Ahmad S, Elsherbiny NM, Haque R, Khan MB, Ishrat T, Shah ZA, Khan MM, Ali M, Jamal A, Katare DP, Liou GI, Bhatia K.

Neurotoxicology. 2014 Dec;45:100-10. doi: 10.1016/j.neuro.2014.10.002. Epub 2014 Oct 12.

PMID:
25316624
18.

Compound 21 is pro-angiogenic in the brain and results in sustained recovery after ischemic stroke.

Alhusban A, Fouda AY, Bindu Pillai, Ishrat T, Soliman S, Fagan SC.

J Hypertens. 2015 Jan;33(1):170-80. doi: 10.1097/HJH.0000000000000364.

PMID:
25304472
19.

Role of inflammasome activation in the pathophysiology of vascular diseases of the neurovascular unit.

Mohamed IN, Ishrat T, Fagan SC, El-Remessy AB.

Antioxid Redox Signal. 2015 May 1;22(13):1188-206. doi: 10.1089/ars.2014.6126. Epub 2014 Nov 11. Review.

20.

Role of matrix metalloproteinase activity in the neurovascular protective effects of Angiotensin antagonism.

Ishrat T, Kozak A, Alhusban A, Pillai B, Johnson MH, El-Remessy AB, Ergul A, Fagan SC.

Stroke Res Treat. 2014;2014:560491. doi: 10.1155/2014/560491. Epub 2014 Jul 24.

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