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Items: 1 to 20 of 69


Screening for mismatch repair deficiency in colorectal cancer: data from three academic medical centers.

O'Kane GM, Ryan É, McVeigh TP, Creavin B, Hyland JM, O'Donoghue DP, Keegan D, Geraghty R, Flannery D, Nolan C, Donovan E, Mehigan BJ, McCormick P, Muldoon C, Farrell M, Shields C, Mulligan N, Kennedy MJ, Green AJ, Winter DC, MacMathuna P, Sheahan K, Gallagher DJ.

Cancer Med. 2017 Jun;6(6):1465-1472. doi: 10.1002/cam4.1025. Epub 2017 May 3.


Microsatellite instability is associated with reduced disease specific survival in stage III colon cancer.

Mohan HM, Ryan E, Balasubramanian I, Kennelly R, Geraghty R, Sclafani F, Fennelly D, McDermott R, Ryan EJ, O'Donoghue D, Hyland JM, Martin ST, O'Connell PR, Gibbons D, Winter D, Sheahan K.

Eur J Surg Oncol. 2016 Nov;42(11):1680-1686. doi: 10.1016/j.ejso.2016.05.013. Epub 2016 Jun 22.


The lymph node ratio does not provide additional prognostic information compared with the N1/N2 classification in Stage III colon cancer.

Mohan HM, Walsh C, Kennelly R, Ng CH, O'Connell PR, Hyland JM, Hanly A, Martin S, Gibbons D, Sheahan K, Winter DC.

Colorectal Dis. 2017 Feb;19(2):165-171. doi: 10.1111/codi.13410.


Enrichment of Inflammatory IL-17 and TNF-α Secreting CD4(+) T Cells within Colorectal Tumors despite the Presence of Elevated CD39(+) T Regulatory Cells and Increased Expression of the Immune Checkpoint Molecule, PD-1.

Dunne MR, Ryan C, Nolan B, Tosetto M, Geraghty R, Winter DC, O'Connell PR, Hyland JM, Doherty GA, Sheahan K, Ryan EJ, Fletcher JM.

Front Oncol. 2016 Mar 7;6:50. doi: 10.3389/fonc.2016.00050. eCollection 2016.


Brain metastasis from colorectal carcinoma: a single cancer centre experience.

Tevlin R, Larkin JO, Hyland JM, O'Connell PR, Winter DC.

Ir J Med Sci. 2015 Sep;184(3):673-5. doi: 10.1007/s11845-015-1272-y. Epub 2015 Mar 24.


Tumour microenvironment of both early- and late-stage colorectal cancer is equally immunosuppressive.

O'Toole A, Michielsen AJ, Nolan B, Tosetto M, Sheahan K, Mulcahy HE, Winter DC, Hyland JM, O'Connell PR, Fennelly D, O'Donoghue D, O'Sullivan J, Doherty GA, Ryan EJ.

Br J Cancer. 2014 Aug 26;111(5):927-32. doi: 10.1038/bjc.2014.367. Epub 2014 Jul 24.


Open versus laparoscopic abdominal rectopexy: an examination of early postoperative outcomes.

Tevlin R, Hanly AM, Rogers AC, Hyland JM, Winter DC, Brannigan AE, O'Connell PR.

Ir J Med Sci. 2015 Jun;184(2):389-93. doi: 10.1007/s11845-014-1125-0. Epub 2014 Apr 30.


Primary colorectal lymphoma - A single centre experience.

Tevlin R, Larkin JO, Hyland JM, O'Connell PR, Winter DC.

Surgeon. 2015 Jun;13(3):151-5. doi: 10.1016/j.surge.2014.01.002. Epub 2014 Mar 30.


Depth-dependent differences in community structure of the human colonic microbiota in health.

Lavelle A, Lennon G, Docherty N, Balfe A, Mulcahy HE, Doherty G, O Donoghue D, Hyland JM, Shanahan F, Sheahan K, Coffey JC, Winter DC, O Connell PR.

PLoS One. 2013 Nov 6;8(11):e78835. doi: 10.1371/journal.pone.0078835. eCollection 2013.


Prognostic significance of tumor budding in rectal cancer biopsies before neoadjuvant therapy.

Rogers AC, Gibbons D, Hanly AM, Hyland JM, O'Connell PR, Winter DC, Sheahan K.

Mod Pathol. 2014 Jan;27(1):156-62. doi: 10.1038/modpathol.2013.124. Epub 2013 Jul 26.


A comparative study of short- and medium-term outcomes comparing emergent surgery and stenting as a bridge to surgery in patients with acute malignant colonic obstruction.

Kavanagh DO, Nolan B, Judge C, Hyland JM, Mulcahy HE, O'Connell PR, Winter DC, Doherty GA.

Dis Colon Rectum. 2013 Apr;56(4):433-40. doi: 10.1097/DCR.0b013e3182760506.


Management of colorectal cancer in patients with inflammatory bowel disease.

Kavanagh DO, Carter MC, Keegan D, Doherty G, Smith MJ, Hyland JM, Mulcahy H, Sheahan K, O' Connell PR, O' Donoghue DP, Winter DC.

Tech Coloproctol. 2014 Jan;18(1):23-8. doi: 10.1007/s10151-013-0981-3. Epub 2013 Feb 14.


Inhibition of dendritic cell maturation by the tumor microenvironment correlates with the survival of colorectal cancer patients following bevacizumab treatment.

Michielsen AJ, Noonan S, Martin P, Tosetto M, Marry J, Biniecka M, Maguire AA, Hyland JM, Sheahan KD, O'Donoghue DP, Mulcahy HE, Fennelly D, Ryan EJ, O'Sullivan JN.

Mol Cancer Ther. 2012 Aug;11(8):1829-37. doi: 10.1158/1535-7163.MCT-12-0162. Epub 2012 Jun 6.


Stage II colonic adenocarcinoma: a detailed study of pT4N0 with emphasis on peritoneal involvement and the role of tumour budding.

Canney AL, Kevans D, Wang LM, Hyland JM, Mulcahy HE, O'Donoghue DP, O'Sullivan J, Geraghty R, Sheahan K.

Histopathology. 2012 Sep;61(3):488-96. doi: 10.1111/j.1365-2559.2012.04250.x. Epub 2012 Mar 28.


Management of synchronous rectal and prostate cancer.

Kavanagh DO, Quinlan DM, Armstrong JG, Hyland JM, O'Connell PR, Winter DC.

Int J Colorectal Dis. 2012 Nov;27(11):1501-8. doi: 10.1007/s00384-012-1465-z. Epub 2012 Mar 28.


A prospective analysis of patient outcome following treatment of T3 rectal cancer with neo-adjuvant chemoradiotherapy and transanal excision.

Kennelly RP, Heeney A, White A, Fennelly D, Sheahan K, Hyland JM, O'Connell PR, Winter DC.

Int J Colorectal Dis. 2012 Jun;27(6):759-64. doi: 10.1007/s00384-011-1388-0. Epub 2011 Dec 17.


Tumour tissue microenvironment can inhibit dendritic cell maturation in colorectal cancer.

Michielsen AJ, Hogan AE, Marry J, Tosetto M, Cox F, Hyland JM, Sheahan KD, O'Donoghue DP, Mulcahy HE, Ryan EJ, O'Sullivan JN.

PLoS One. 2011;6(11):e27944. doi: 10.1371/journal.pone.0027944. Epub 2011 Nov 18.


The use of minimally invasive surgery in the management of idiopathic omental torsion: The diagnostic and therapeutic role of laparoscopy.

Peirce C, Martin ST, Hyland JM.

Int J Surg Case Rep. 2011;2(6):125-7. doi: 10.1016/j.ijscr.2011.02.012. Epub 2011 Mar 31.


How I do it: the stapled ileal J pouch at restorative proctocolectomy.

Martin ST, Tevlin R, Heeney A, Peirce C, Hyland JM, Winter DC.

Tech Coloproctol. 2011 Dec;15(4):451-4. doi: 10.1007/s10151-011-0757-6. Epub 2011 Oct 5.


Use of an electrothermal bipolar sealing device in ligation of major mesenteric vessels during laparoscopic colorectal resection.

Martin ST, Heeney A, Pierce C, O'Connell PR, Hyland JM, Winter DC.

Tech Coloproctol. 2011 Sep;15(3):285-9. doi: 10.1007/s10151-011-0707-3. Epub 2011 Jul 15.


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