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Items: 1 to 20 of 145

1.

Effectiveness of methylcobalamin and folinic Acid treatment on adaptive behavior in children with autistic disorder is related to glutathione redox status.

Frye RE, Melnyk S, Fuchs G, Reid T, Jernigan S, Pavliv O, Hubanks A, Gaylor DW, Walters L, James SJ.

Autism Res Treat. 2013;2013:609705. doi: 10.1155/2013/609705. Epub 2013 Oct 12.

2.

Development of a chronic noncancer oral reference dose and drinking water screening level for sulfolane using benchmark dose modeling.

Thompson CM, Gaylor DW, Tachovsky JA, Perry C, Carakostas MC, Haws LC.

J Appl Toxicol. 2013 Dec;33(12):1395-406. doi: 10.1002/jat.2799. Epub 2012 Aug 31.

PMID:
22936336
3.

Metabolic imbalance associated with methylation dysregulation and oxidative damage in children with autism.

Melnyk S, Fuchs GJ, Schulz E, Lopez M, Kahler SG, Fussell JJ, Bellando J, Pavliv O, Rose S, Seidel L, Gaylor DW, James SJ.

J Autism Dev Disord. 2012 Mar;42(3):367-77. doi: 10.1007/s10803-011-1260-7.

4.

A functional polymorphism in the reduced folate carrier gene and DNA hypomethylation in mothers of children with autism.

James SJ, Melnyk S, Jernigan S, Pavliv O, Trusty T, Lehman S, Seidel L, Gaylor DW, Cleves MA.

Am J Med Genet B Neuropsychiatr Genet. 2010 Sep;153B(6):1209-20. doi: 10.1002/ajmg.b.31094.

5.

Pathology Working Group review and evaluation of proliferative lesions of mammary gland tissues in female rats fed ammonium perfluorooctanoate (APFO) in the diet for 2 years.

Hardisty JF, Willson GA, Brown WR, McConnell EE, Frame SR, Gaylor DW, Kennedy GL, Butenhoff JL.

Drug Chem Toxicol. 2010 Apr;33(2):131-7. doi: 10.3109/01480541003667610.

PMID:
20307141
6.

Cellular and mitochondrial glutathione redox imbalance in lymphoblastoid cells derived from children with autism.

James SJ, Rose S, Melnyk S, Jernigan S, Blossom S, Pavliv O, Gaylor DW.

FASEB J. 2009 Aug;23(8):2374-83. doi: 10.1096/fj.08-128926. Epub 2009 Mar 23.

7.

Efficacy of methylcobalamin and folinic acid treatment on glutathione redox status in children with autism.

James SJ, Melnyk S, Fuchs G, Reid T, Jernigan S, Pavliv O, Hubanks A, Gaylor DW.

Am J Clin Nutr. 2009 Jan;89(1):425-30. doi: 10.3945/ajcn.2008.26615. Epub 2008 Dec 3.

8.

Abnormal Transmethylation/transsulfuration Metabolism and DNA Hypomethylation Among Parents of Children with Autism.

James SJ, Melnyk S, Jernigan S, Hubanks A, Rose S, Gaylor DW.

J Autism Dev Disord. 2008 Nov;38(10):1976. doi: 10.1007/s10803-008-0614-2. No abstract available.

PMID:
19011973
9.

Abnormal transmethylation/transsulfuration metabolism and DNA hypomethylation among parents of children with autism.

James SJ, Melnyk S, Jernigan S, Hubanks A, Rose S, Gaylor DW.

J Autism Dev Disord. 2008 Nov;38(10):1966-75. doi: 10.1007/s10803-008-0591-5. Epub 2008 May 30. Erratum in: J Autism Dev Disord. 2008 Nov;38(10):1976. Jill James, S [corrected to James, S Jill].

10.

Dose-response relationships for cancer incidence reflect susceptibility distributions.

Lutz WK, Gaylor DW.

Chem Res Toxicol. 2008 May;21(5):971-2; author reply 972-3. doi: 10.1021/tx800090a. Epub 2008 Apr 23. No abstract available.

PMID:
18429623
11.

Metabolic endophenotype and related genotypes are associated with oxidative stress in children with autism.

James SJ, Melnyk S, Jernigan S, Cleves MA, Halsted CH, Wong DH, Cutler P, Bock K, Boris M, Bradstreet JJ, Baker SM, Gaylor DW.

Am J Med Genet B Neuropsychiatr Genet. 2006 Dec 5;141B(8):947-56.

12.

Population variability in biological adaptive responses to DNA damage and the shapes of carcinogen dose-response curves.

Conolly RB, Gaylor DW, Lutz WK.

Toxicol Appl Pharmacol. 2005 Sep 1;207(2 Suppl):570-5. Review.

PMID:
15996697
13.
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15.

Are tumor incidence rates from chronic bioassays telling us what we need to know about carcinogens?

Gaylor DW.

Regul Toxicol Pharmacol. 2005 Mar;41(2):128-33. Epub 2004 Dec 19.

PMID:
15698536
16.

Role of the standard deviation in the estimation of benchmark doses with continuous data.

Gaylor DW, Slikker W Jr.

Risk Anal. 2004 Dec;24(6):1683-7.

PMID:
15660621
17.

Metabolic biomarkers of increased oxidative stress and impaired methylation capacity in children with autism.

James SJ, Cutler P, Melnyk S, Jernigan S, Janak L, Gaylor DW, Neubrander JA.

Am J Clin Nutr. 2004 Dec;80(6):1611-7.

PMID:
15585776
18.

Dose-dependent transitions in mechanisms of toxicity: case studies.

Slikker W Jr, Andersen ME, Bogdanffy MS, Bus JS, Cohen SD, Conolly RB, David RM, Doerrer NG, Dorman DC, Gaylor DW, Hattis D, Rogers JM, Setzer RW, Swenberg JA, Wallace K.

Toxicol Appl Pharmacol. 2004 Dec 15;201(3):226-94. Review.

PMID:
15582646
19.

Dose-dependent transitions in mechanisms of toxicity.

Slikker W Jr, Andersen ME, Bogdanffy MS, Bus JS, Cohen SD, Conolly RB, David RM, Doerrer NG, Dorman DC, Gaylor DW, Hattis D, Rogers JM, Setzer RW, Swenberg JA, Wallace K.

Toxicol Appl Pharmacol. 2004 Dec 15;201(3):203-25. Review.

PMID:
15582645
20.

A comparison of microbial dose-response models fitted to human data.

Moon H, Chen JJ, Gaylor DW, Kodell RL.

Regul Toxicol Pharmacol. 2004 Oct;40(2):177-84.

PMID:
15450720

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