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Items: 19

1.

Fibroblast growth factors (FGFs) prime the limb specific Shh enhancer for chromatin changes that balance histone acetylation mediated by E26 transformation-specific (ETS) factors.

Peluso S, Douglas A, Hill A, De Angelis C, Moore BL, Grimes G, Petrovich G, Essafi A, Hill RE.

Elife. 2017 Sep 26;6. pii: e28590. doi: 10.7554/eLife.28590.

2.

Mutations in HNF1A result in marked alterations of plasma glycan profile.

Thanabalasingham G, Huffman JE, Kattla JJ, Novokmet M, Rudan I, Gloyn AL, Hayward C, Adamczyk B, Reynolds RM, Muzinic A, Hassanali N, Pucic M, Bennett AJ, Essafi A, Polasek O, Mughal SA, Redzic I, Primorac D, Zgaga L, Kolcic I, Hansen T, Gasperikova D, Tjora E, Strachan MW, Nielsen T, Stanik J, Klimes I, Pedersen OB, Njølstad PR, Wild SH, Gyllensten U, Gornik O, Wilson JF, Hastie ND, Campbell H, McCarthy MI, Rudd PM, Owen KR, Lauc G, Wright AF.

Diabetes. 2013 Apr;62(4):1329-37. doi: 10.2337/db12-0880. Epub 2012 Dec 28.

3.

Opposing functions of the ETS factor family define Shh spatial expression in limb buds and underlie polydactyly.

Lettice LA, Williamson I, Wiltshire JH, Peluso S, Devenney PS, Hill AE, Essafi A, Hagman J, Mort R, Grimes G, DeAngelis CL, Hill RE.

Dev Cell. 2012 Feb 14;22(2):459-67. doi: 10.1016/j.devcel.2011.12.010.

4.

A wt1-controlled chromatin switching mechanism underpins tissue-specific wnt4 activation and repression.

Essafi A, Webb A, Berry RL, Slight J, Burn SF, Spraggon L, Velecela V, Martinez-Estrada OM, Wiltshire JH, Roberts SG, Brownstein D, Davies JA, Hastie ND, Hohenstein P.

Dev Cell. 2011 Sep 13;21(3):559-74. doi: 10.1016/j.devcel.2011.07.014. Epub 2011 Aug 25.

5.

Genomics meets glycomics-the first GWAS study of human N-Glycome identifies HNF1α as a master regulator of plasma protein fucosylation.

Lauc G, Essafi A, Huffman JE, Hayward C, Knežević A, Kattla JJ, Polašek O, Gornik O, Vitart V, Abrahams JL, Pučić M, Novokmet M, Redžić I, Campbell S, Wild SH, Borovečki F, Wang W, Kolčić I, Zgaga L, Gyllensten U, Wilson JF, Wright AF, Hastie ND, Campbell H, Rudd PM, Rudan I.

PLoS Genet. 2010 Dec 23;6(12):e1001256. doi: 10.1371/journal.pgen.1001256.

6.

Shaping melons: agronomic and genetic characterization of QTLs that modify melon fruit morphology.

Fernandez-Silva I, Moreno E, Essafi A, Fergany M, Garcia-Mas J, Martín-Hernandez AM, Alvarez JM, Monforte AJ.

Theor Appl Genet. 2010 Sep;121(5):931-40. doi: 10.1007/s00122-010-1361-2. Epub 2010 May 27.

PMID:
20506012
7.

WT1 the oncogene: a tale of death and HtrA.

Essafi A, Hastie ND.

Mol Cell. 2010 Jan 29;37(2):153-5. doi: 10.1016/j.molcel.2010.01.010.

8.

Wt1 is required for cardiovascular progenitor cell formation through transcriptional control of Snail and E-cadherin.

Martínez-Estrada OM, Lettice LA, Essafi A, Guadix JA, Slight J, Velecela V, Hall E, Reichmann J, Devenney PS, Hohenstein P, Hosen N, Hill RE, Muñoz-Chapuli R, Hastie ND.

Nat Genet. 2010 Jan;42(1):89-93. doi: 10.1038/ng.494. Epub 2009 Dec 20.

9.

Highly conserved non-coding elements on either side of SOX9 associated with Pierre Robin sequence.

Benko S, Fantes JA, Amiel J, Kleinjan DJ, Thomas S, Ramsay J, Jamshidi N, Essafi A, Heaney S, Gordon CT, McBride D, Golzio C, Fisher M, Perry P, Abadie V, Ayuso C, Holder-Espinasse M, Kilpatrick N, Lees MM, Picard A, Temple IK, Thomas P, Vazquez MP, Vekemans M, Roest Crollius H, Hastie ND, Munnich A, Etchevers HC, Pelet A, Farlie PG, Fitzpatrick DR, Lyonnet S.

Nat Genet. 2009 Mar;41(3):359-64. doi: 10.1038/ng.329. Epub 2009 Feb 22.

PMID:
19234473
10.

Studying the subcellular localization and DNA-binding activity of FoxO transcription factors, downstream effectors of PI3K/Akt.

Essafi A, Gomes AR, Pomeranz KM, Zwolinska AK, Varshochi R, McGovern UB, Lam EW.

Methods Mol Biol. 2009;462:201-11. doi: 10.1007/978-1-60327-115-8_13.

PMID:
19160671
11.

Dissection of the oligogenic resistance to Cucumber mosaic virus in the melon accession PI 161375.

Essafi A, Díaz-Pendón JA, Moriones E, Monforte AJ, Garcia-Mas J, Martín-Hernández AM.

Theor Appl Genet. 2009 Jan;118(2):275-84. doi: 10.1007/s00122-008-0897-x. Epub 2008 Sep 30.

PMID:
18825359
12.

Induction of Mxi1-SR alpha by FOXO3a contributes to repression of Myc-dependent gene expression.

Delpuech O, Griffiths B, East P, Essafi A, Lam EW, Burgering B, Downward J, Schulze A.

Mol Cell Biol. 2007 Jul;27(13):4917-30. Epub 2007 Apr 23.

13.

[Recurrent hydatidiform mole. Case report of 9 successive molar pregnancies].

Sahraoui W, Hajji S, Haouas N, Ladib N, Essafi A, Hmissa S, Bibi M, Khairi H.

Tunis Med. 2006 Aug;84(8):506-8. French.

PMID:
17175694
14.

FOXO3a induces differentiation of Bcr-Abl-transformed cells through transcriptional down-regulation of Id1.

Birkenkamp KU, Essafi A, van der Vos KE, da Costa M, Hui RC, Holstege F, Koenderman L, Lam EW, Coffer PJ.

J Biol Chem. 2007 Jan 26;282(4):2211-20. Epub 2006 Nov 27.

15.

Epstein-Barr virus represses the FoxO1 transcription factor through latent membrane protein 1 and latent membrane protein 2A.

Shore AM, White PC, Hui RC, Essafi A, Lam EW, Rowe M, Brennan P.

J Virol. 2006 Nov;80(22):11191-9. Epub 2006 Aug 30.

16.

[Prognosis of local recurrence of breast cancer in Tunisia].

Sahraoui W, Essafi A, Laajili H, Haouas N, Hmissa S, Sebri L, Hraiech S, Bibi M, Bouaouina N, Ben Ahmed S, Khairi H.

Tunis Med. 2006 Feb;84(2):97-102. French.

PMID:
16755973
17.

Progestins regulate the expression and activity of the forkhead transcription factor FOXO1 in differentiating human endometrium.

Labied S, Kajihara T, Madureira PA, Fusi L, Jones MC, Higham JM, Varshochi R, Francis JM, Zoumpoulidou G, Essafi A, Fernandez de Mattos S, Lam EW, Brosens JJ.

Mol Endocrinol. 2006 Jan;20(1):35-44. Epub 2005 Aug 25.

PMID:
16123151
18.

Direct transcriptional regulation of Bim by FoxO3a mediates STI571-induced apoptosis in Bcr-Abl-expressing cells.

Essafi A, Fernández de Mattos S, Hassen YA, Soeiro I, Mufti GJ, Thomas NS, Medema RH, Lam EW.

Oncogene. 2005 Mar 31;24(14):2317-29.

PMID:
15688014
19.

FoxO3a and BCR-ABL regulate cyclin D2 transcription through a STAT5/BCL6-dependent mechanism.

Fernández de Mattos S, Essafi A, Soeiro I, Pietersen AM, Birkenkamp KU, Edwards CS, Martino A, Nelson BH, Francis JM, Jones MC, Brosens JJ, Coffer PJ, Lam EW.

Mol Cell Biol. 2004 Nov;24(22):10058-71.

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