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Items: 1 to 20 of 50

1.

Hypercapnia Impairs Na,K-ATPase Function by Inducing Endoplasmic Reticulum Retention of the β-Subunit of the Enzyme in Alveolar Epithelial Cells.

Kryvenko V, Wessendorf M, Morty RE, Herold S, Seeger W, Vagin O, Dada LA, Sznajder JI, Vadász I.

Int J Mol Sci. 2020 Feb 21;21(4). pii: E1467. doi: 10.3390/ijms21041467.

2.

Elevated CO2 regulates the Wnt signaling pathway in mammals, Drosophila melanogaster and Caenorhabditis elegans.

Shigemura M, Lecuona E, Angulo M, Dada LA, Edwards MB, Welch LC, Casalino-Matsuda SM, Sporn PHS, Vadász I, Helenius IT, Nader GA, Gruenbaum Y, Sharabi K, Cummins E, Taylor C, Bharat A, Gottardi CJ, Beitel GJ, Kaminski N, Budinger GRS, Berdnikovs S, Sznajder JI.

Sci Rep. 2019 Dec 3;9(1):18251. doi: 10.1038/s41598-019-54683-0.

3.

Linear ubiquitin assembly complex regulates lung epithelial-driven responses during influenza infection.

Brazee PL, Morales-Nebreda L, Magnani ND, Garcia JG, Misharin AV, Ridge KM, Budinger GRS, Iwai K, Dada LA, Sznajder JI.

J Clin Invest. 2020 Mar 2;130(3):1301-1314. doi: 10.1172/JCI128368.

4.

Influenza A Virus Infection Induces Muscle Wasting via IL-6 Regulation of the E3 Ubiquitin Ligase Atrogin-1.

Radigan KA, Nicholson TT, Welch LC, Chi M, Amarelle L, Angulo M, Shigemura M, Shigemura A, Runyan CE, Morales-Nebreda L, Perlman H, Ceco E, Lecuona E, Dada LA, Misharin AV, Mutlu GM, Sznajder JI, Budinger GRS.

J Immunol. 2019 Jan 15;202(2):484-493. doi: 10.4049/jimmunol.1701433. Epub 2018 Dec 7.

5.

Ubiquitin-proteasome signaling in lung injury.

Magnani ND, Dada LA, Sznajder JI.

Transl Res. 2018 Aug;198:29-39. doi: 10.1016/j.trsl.2018.04.003. Epub 2018 Apr 23. Review.

6.

Splice Wars: The Role of MLCK Isoforms in Ventilation-induced Lung Injury.

Brazee PL, Dada LA.

Am J Respir Cell Mol Biol. 2018 May;58(5):549-550. doi: 10.1165/rcmb.2017-0385ED. No abstract available.

7.

HIF and HOIL-1L-mediated PKCζ degradation stabilizes plasma membrane Na,K-ATPase to protect against hypoxia-induced lung injury.

Magnani ND, Dada LA, Queisser MA, Brazee PL, Welch LC, Anekalla KR, Zhou G, Vagin O, Misharin AV, Budinger GRS, Iwai K, Ciechanover AJ, Sznajder JI.

Proc Natl Acad Sci U S A. 2017 Nov 21;114(47):E10178-E10186. doi: 10.1073/pnas.1713563114. Epub 2017 Nov 6.

8.

Downregulation of PKCζ/Pard3/Pard6b is responsible for lung adenocarcinoma cell EMT and invasion.

Zhou Q, Dai J, Chen T, Dada LA, Zhang X, Zhang W, DeCamp MM, Winn RA, Sznajder JI, Zhou G.

Cell Signal. 2017 Oct;38:49-59. doi: 10.1016/j.cellsig.2017.06.016. Epub 2017 Jun 24.

9.

FXYD5 Is an Essential Mediator of the Inflammatory Response during Lung Injury.

Brazee PL, Soni PN, Tokhtaeva E, Magnani N, Yemelyanov A, Perlman HR, Ridge KM, Sznajder JI, Vagin O, Dada LA.

Front Immunol. 2017 Jun 1;8:623. doi: 10.3389/fimmu.2017.00623. eCollection 2017.

10.

Selective Assembly of Na,K-ATPase α2β2 Heterodimers in the Heart: DISTINCT FUNCTIONAL PROPERTIES AND ISOFORM-SELECTIVE INHIBITORS.

Habeck M, Tokhtaeva E, Nadav Y, Ben Zeev E, Ferris SP, Kaufman RJ, Bab-Dinitz E, Kaplan JH, Dada LA, Farfel Z, Tal DM, Katz A, Sachs G, Vagin O, Karlish SJ.

J Biol Chem. 2016 Oct 28;291(44):23159-23174. Epub 2016 Sep 13.

11.

The O-glycosylated ectodomain of FXYD5 impairs adhesion by disrupting cell-cell trans-dimerization of Na,K-ATPase β1 subunits.

Tokhtaeva E, Sun H, Deiss-Yehiely N, Wen Y, Soni PN, Gabrielli NM, Marcus EA, Ridge KM, Sachs G, Vazquez-Levin M, Sznajder JI, Vagin O, Dada LA.

J Cell Sci. 2016 Jun 15;129(12):2394-406. doi: 10.1242/jcs.186148. Epub 2016 May 3.

12.

FXYD5 Protein Has a Pro-inflammatory Role in Epithelial Cells.

Lubarski-Gotliv I, Asher C, Dada LA, Garty H.

J Biol Chem. 2016 May 20;291(21):11072-82. doi: 10.1074/jbc.M115.699041. Epub 2016 Mar 22.

13.

Role of Linear Ubiquitination in Health and Disease.

Brazee P, Dada LA, Sznajder JI.

Am J Respir Cell Mol Biol. 2016 Jun;54(6):761-8. doi: 10.1165/rcmb.2016-0014TR. Review.

14.

High CO2 Leads to Na,K-ATPase Endocytosis via c-Jun Amino-Terminal Kinase-Induced LMO7b Phosphorylation.

Dada LA, Trejo Bittar HE, Welch LC, Vagin O, Deiss-Yehiely N, Kelly AM, Baker MR, Capri J, Cohn W, Whitelegge JP, Vadász I, Gruenbaum Y, Sznajder JI.

Mol Cell Biol. 2015 Dec;35(23):3962-73. doi: 10.1128/MCB.00813-15. Epub 2015 Sep 14.

15.

High CO2 levels cause skeletal muscle atrophy via AMP-activated kinase (AMPK), FoxO3a protein, and muscle-specific Ring finger protein 1 (MuRF1).

Jaitovich A, Angulo M, Lecuona E, Dada LA, Welch LC, Cheng Y, Gusarova G, Ceco E, Liu C, Shigemura M, Barreiro E, Patterson C, Nader GA, Sznajder JI.

J Biol Chem. 2015 Apr 3;290(14):9183-94. doi: 10.1074/jbc.M114.625715. Epub 2015 Feb 17.

16.

Septin dynamics are essential for exocytosis.

Tokhtaeva E, Capri J, Marcus EA, Whitelegge JP, Khuzakhmetova V, Bukharaeva E, Deiss-Yehiely N, Dada LA, Sachs G, Fernandez-Salas E, Vagin O.

J Biol Chem. 2015 Feb 27;290(9):5280-97. doi: 10.1074/jbc.M114.616201. Epub 2015 Jan 9.

17.

Intratracheal administration of influenza virus is superior to intranasal administration as a model of acute lung injury.

Morales-Nebreda L, Chi M, Lecuona E, Chandel NS, Dada LA, Ridge K, Soberanes S, Nigdelioglu R, Sznajder JI, Mutlu GM, Budinger GR, Radigan KA.

J Virol Methods. 2014 Dec;209:116-20. doi: 10.1016/j.jviromet.2014.09.004. Epub 2014 Sep 17.

18.

HOIL-1L functions as the PKCζ ubiquitin ligase to promote lung tumor growth.

Queisser MA, Dada LA, Deiss-Yehiely N, Angulo M, Zhou G, Kouri FM, Knab LM, Liu J, Stegh AH, DeCamp MM, Budinger GR, Chandel NS, Ciechanover A, Iwai K, Sznajder JI.

Am J Respir Crit Care Med. 2014 Sep 15;190(6):688-98. doi: 10.1164/rccm.201403-0463OC.

19.

Evolutionary conserved role of c-Jun-N-terminal kinase in CO2-induced epithelial dysfunction.

Vadász I, Dada LA, Briva A, Helenius IT, Sharabi K, Welch LC, Kelly AM, Grzesik BA, Budinger GR, Liu J, Seeger W, Beitel GJ, Gruenbaum Y, Sznajder JI.

PLoS One. 2012;7(10):e46696. doi: 10.1371/journal.pone.0046696. Epub 2012 Oct 8.

20.

Lord of the RING: ubiquitination and directed degradation of skeletal muscle in acute lung injury.

Vadász I, Dada LA, Maltais F.

Am J Respir Crit Care Med. 2012 Apr 15;185(8):795-6. doi: 10.1164/rccm.201202-0225ED. No abstract available.

PMID:
22505748

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