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Items: 1 to 20 of 92


Structure-activity relationship study of angiotensin II analogs in terms of β-arrestin-dependent signaling to aldosterone production.

Valero TR, Sturchler E, Jafferjee M, Rengo G, Magafa V, Cordopatis P, McDonald P, Koch WJ, Lymperopoulos A.

Pharmacol Res Perspect. 2016 Mar 8;4(2):e00226. doi: 10.1002/prp2.226. eCollection 2016 Apr.


Glutathione analogues as substrates or inhibitors that discriminate between allozymes of the MDR-involved human glutathione transferase P1-1.

Zompra A, Georgakis N, Pappa E, Thireou T, Eliopoulos E, Labrou N, Cordopatis P, Clonis Y.

Biopolymers. 2016 May;106(3):330-44. doi: 10.1002/bip.22844.


Structural studies and cytotoxicity assays of "aggregation-prone" IAPP(8-16) and its non-amyloidogenic variants suggest its important role in fibrillogenesis and cytotoxicity of human amylin.

Louros NN, Tsiolaki PL, Zompra AA, Pappa EV, Magafa V, Pairas G, Cordopatis P, Cheimonidou C, Trougakos IP, Iconomidou VA, Hamodrakas SJ.

Biopolymers. 2015 May;104(3):196-205. doi: 10.1002/bip.22650.


Involvement of angiotensin II type 2 receptor (AT2R) signaling in human pancreatic ductal adenocarcinoma (PDAC): a novel AT2R agonist effectively attenuates growth of PDAC grafts in mice.

Ishiguro S, Yoshimura K, Tsunedomi R, Oka M, Takao S, Inui M, Kawabata A, Wall T, Magafa V, Cordopatis P, Tzakos AG, Tamura M.

Cancer Biol Ther. 2015;16(2):307-16. doi: 10.1080/15384047.2014.1002357.


Structural studies of "aggregation-prone" peptide-analogues of teleostean egg chorion ZPB proteins.

Louros NN, Petronikolou N, Karamanos T, Cordopatis P, Iconomidou VA, Hamodrakas SJ.

Biopolymers. 2014 Nov;102(6):427-36. doi: 10.1002/bip.22563.


The thyroxine-containing thyroglobulin peptide (aa 2549-2560) is a target epitope in iodide-accelerated spontaneous autoimmune thyroiditis.

Kolypetri P, Carayanniotis K, Rahman S, Georghiou PE, Magafa V, Cordopatis P, Carayanniotis G.

J Immunol. 2014 Jul 1;193(1):96-101. doi: 10.4049/jimmunol.1400561. Epub 2014 May 30.


Electronic sculpting of ligand-GPCR subtype selectivity: the case of angiotensin II.

Magnani F, Pappas CG, Crook T, Magafa V, Cordopatis P, Ishiguro S, Ohta N, Selent J, Bosnyak S, Jones ES, Gerothanassis IP, Tamura M, Widdop RE, Tzakos AG.

ACS Chem Biol. 2014 Jul 18;9(7):1420-5. doi: 10.1021/cb500063y. Epub 2014 May 14.


[DOTA]Somatostatin-14 analogs and their (111)In-radioligands: effects of decreasing ring-size on sst1-5 profile, stability and tumor targeting.

Tatsi A, Maina T, Cescato R, Waser B, Krenning EP, de Jong M, Cordopatis P, Reubi JC, Nock BA.

Eur J Med Chem. 2014 Feb 12;73:30-7. doi: 10.1016/j.ejmech.2013.12.003. Epub 2013 Dec 16.


Structure-activity studies of lGnRH-III through rational amino acid substitution and NMR conformational studies.

Pappa EV, Zompra AA, Diamantopoulou Z, Spyranti Z, Pairas G, Lamari FN, Katsoris P, Spyroulias GA, Cordopatis P.

Biopolymers. 2012;98(6):525-34. doi: 10.1002/bip.22123.


[111In-DOTA]Somatostatin-14 analogs as potential pansomatostatin-like radiotracers - first results of a preclinical study.

Tatsi A, Maina T, Cescato R, Waser B, Krenning EP, de Jong M, Cordopatis P, Reubi JC, Nock BA.

EJNMMI Res. 2012 Jun 9;2(1):25. doi: 10.1186/2191-219X-2-25.


Pleiotrophin expression and role in physiological angiogenesis in vivo: potential involvement of nucleolin.

Koutsioumpa M, Drosou G, Mikelis C, Theochari K, Vourtsis D, Katsoris P, Giannopoulou E, Courty J, Petrou C, Magafa V, Cordopatis P, Papadimitriou E.

Vasc Cell. 2012 Mar 16;4:4. doi: 10.1186/2045-824X-4-4.


The silkmoth eggshell as a natural amyloid shield for the safe development of insect oocyte and embryo: insights from studies of silkmoth chorion protein peptide-analogues of the B family.

Iconomidou VA, Cordopatis P, Hoenger A, Hamodrakas SJ.

Biopolymers. 2011;96(6):723-33. doi: 10.1002/bip.21606. Epub 2011 Feb 18.


Clinical outcome of patients with various advanced cancer types vaccinated with an optimized cryptic human telomerase reverse transcriptase (TERT) peptide: results of an expanded phase II study.

Kotsakis A, Vetsika EK, Christou S, Hatzidaki D, Vardakis N, Aggouraki D, Konsolakis G, Georgoulias V, Christophyllakis Ch, Cordopatis P, Kosmatopoulos K, Mavroudis D.

Ann Oncol. 2012 Feb;23(2):442-9. doi: 10.1093/annonc/mdr396. Epub 2011 Aug 25.


Insights into ectopic estrogen receptor expression, nucleocytoplasmic distribution and interaction with chromatin obtained with new antibodies to estrogen receptors α and β.

Chantzi NI, Meligova AK, Dhimolea E, Petrou CC, Mitsiou DJ, Magafa V, Pechtelidou A, Florentin I, Kitraki E, Cordopatis P, Tiniakos DG, Alexis MN.

Steroids. 2011 Sep-Oct;76(10-11):974-85. doi: 10.1016/j.steroids.2011.05.010. Epub 2011 Jun 29.


A new validated SPE-HPLC method for monitoring crocetin in human plasma--application after saffron tea consumption.

Chryssanthi DG, Lamari FN, Georgakopoulos CD, Cordopatis P.

J Pharm Biomed Anal. 2011 Jun 1;55(3):563-8. doi: 10.1016/j.jpba.2011.02.018. Epub 2011 Feb 21.


A peptide corresponding to the C-terminal region of pleiotrophin inhibits angiogenesis in vivo and in vitro.

Mikelis C, Lamprou M, Koutsioumpa M, Koutsioubas AG, Spyranti Z, Zompra AA, Spiliopoulos N, Vradis AA, Katsoris P, Spyroulias GA, Cordopatis P, Courty J, Papadimitriou E.

J Cell Biochem. 2011 Jun;112(6):1532-43. doi: 10.1002/jcb.23066.


Memory enhancing effects of saffron in aged mice are correlated with antioxidant protection.

Papandreou MA, Tsachaki M, Efthimiopoulos S, Cordopatis P, Lamari FN, Margarity M.

Behav Brain Res. 2011 Jun 1;219(2):197-204. doi: 10.1016/j.bbr.2011.01.007. Epub 2011 Jan 14.


Crocetin inhibits invasiveness of MDA-MB-231 breast cancer cells via downregulation of matrix metalloproteinases.

Chryssanthi DG, Dedes PG, Karamanos NK, Cordopatis P, Lamari FN.

Planta Med. 2011 Jan;77(2):146-51. doi: 10.1055/s-0030-1250178. Epub 2010 Aug 27.


Synthesis and Biological Evaluation of New CRH Analogues.

Papazacharias S, Magafa V, Bernad N, Pairas G, Spyroulias GA, Martinez J, Cordopatis P.

Bioinorg Chem Appl. 2010. pii: 252348. doi: 10.1155/2010/252348. Epub 2010 Jun 28.


Synthetic peptides as structural maquettes of Angiotensin-I converting enzyme catalytic sites.

Spyranti Z, Galanis AS, Pairas G, Spyroulias GA, Manessi-Zoupa E, Cordopatis P.

Bioinorg Chem Appl. 2010:820476. doi: 10.1155/2010/820476. Epub 2010 Jun 9.

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