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Items: 1 to 20 of 166


A Controlled Fermented Samjunghwan Herbal Formula Ameliorates Non-alcoholic Hepatosteatosis in HepG2 Cells and OLETF Rats.

Ansari A, Bose S, Patra JK, Shin NR, Lim DW, Kim KW, Wang JH, Kim YM, Chin YW, Kim H.

Front Pharmacol. 2018 Jun 19;9:596. doi: 10.3389/fphar.2018.00596. eCollection 2018.


Alpha-Mangostin Improves Insulin Secretion and Protects INS-1 Cells from Streptozotocin-Induced Damage.

Lee D, Kim YM, Jung K, Chin YW, Kang KS.

Int J Mol Sci. 2018 May 16;19(5). pii: E1484. doi: 10.3390/ijms19051484.


Correction: Discovery of a FLT3 inhibitor LDD1937 as an anti-leukemic agent for acute myeloid leukemia.

Lee HJ, Lee J, Jeong P, Choi J, Baek J, Ahn SL, Moon Y, Heo JD, Choi YH, Chin YW, Kim YC, Han SY.

Oncotarget. 2018 Apr 13;9(28):20219. doi: 10.18632/oncotarget.25141. eCollection 2018 Apr 13.


Sauchinone controls hepatic cholesterol homeostasis by the negative regulation of PCSK9 transcriptional network.

Chae HS, You BH, Kim DY, Lee H, Ko HW, Ko HJ, Choi YH, Choi SS, Chin YW.

Sci Rep. 2018 Apr 30;8(1):6737. doi: 10.1038/s41598-018-24935-6.


HO-1 dependent antioxidant effects of ethyl acetate fraction from Physalis alkekengi fruit ameliorates scopolamine-induced cognitive impairments.

Moniruzzaman M, Chin YW, Cho J.

Cell Stress Chaperones. 2018 Jul;23(4):763-772. doi: 10.1007/s12192-018-0887-0. Epub 2018 Mar 15.


Two new lathyrane-type diterpenoid glycosides with IL-6 production inhibitory activity from the roots of Euphorbia kansui.

Kim YM, Ahn J, Chae HS, Choi YH, Kim J, Chin YW.

Bioorg Med Chem Lett. 2018 Apr 15;28(7):1207-1210. doi: 10.1016/j.bmcl.2018.02.050. Epub 2018 Feb 27.


Enzyme Kinetics and Molecular Docking Studies on Cytochrome 2B6, 2C19, 2E1, and 3A4 Activities by Sauchinone.

Gong EC, Chea S, Balupuri A, Kang NS, Chin YW, Choi YH.

Molecules. 2018 Mar 2;23(3). pii: E555. doi: 10.3390/molecules23030555.


Discovery of Flavonoids from Scutellaria baicalensis with Inhibitory Activity Against PCSK 9 Expression: Isolation, Synthesis and Their Biological Evaluation.

Nhoek P, Chae HS, Masagalli JN, Mailar K, Pel P, Kim YM, Choi WJ, Chin YW.

Molecules. 2018 Feb 24;23(2). pii: E504. doi: 10.3390/molecules23020504.


Houttuynia cordata extract increased systemic exposure and liver concentrations of metformin through OCTs and MATEs in rats.

You BH, Chin YW, Kim H, Choi HS, Choi YH.

Phytother Res. 2018 Jun;32(6):1004-1013. doi: 10.1002/ptr.6036. Epub 2018 Feb 26.


Discovery of a FLT3 inhibitor LDD1937 as an anti-leukemic agent for acute myeloid leukemia.

Lee HJ, Lee J, Jeong P, Choi J, Baek J, Ahn SJ, Moon Y, Heo JD, Choi YH, Chin YW, Kim YC, Han SY.

Oncotarget. 2017 Dec 14;9(1):924-936. doi: 10.18632/oncotarget.23221. eCollection 2018 Jan 2. Erratum in: Oncotarget. 2018 Apr 13;9(28):20219.


Nardostachys jatamansi Ethanol Extract Ameliorates Aβ42 Cytotoxicity.

Liu QF, Jeon Y, Sung YW, Lee JH, Jeong H, Kim YM, Yun HS, Chin YW, Jeon S, Cho KS, Koo BS.

Biol Pharm Bull. 2018 Apr 1;41(4):470-477. doi: 10.1248/bpb.b17-00750. Epub 2018 Feb 3.


Spiroketones and a Biphenyl Analog from Stems and Leaves of Larrea nitida and Their Inhibitory Activity against IL-6 Production.

Ahn J, Pei Y, Chae HS, Kim SH, Kim YM, Choi YH, Lee J, Chang M, Song YS, Rodriguez R, Oh DC, Kim J, Choi S, Joo SH, Chin YW.

Molecules. 2018 Jan 31;23(2). pii: E302. doi: 10.3390/molecules23020302.


Furylhydroquinones and miscellaneous compounds from the roots of Lithospermum erythrorhizon and their anti-inflammatory effect in HaCaT cells.

Ahn J, Chae HS, Chin YW, Kim J.

Nat Prod Res. 2018 Jan 31:1-8. doi: 10.1080/14786419.2018.1431632. [Epub ahead of print]


Flos Lonicera Combined with Metformin Ameliorates Hepatosteatosis and Glucose Intolerance in Association with Gut Microbiota Modulation.

Shin NR, Bose S, Wang JH, Ansari A, Lim SK, Chin YW, Choi HS, Kim H.

Front Microbiol. 2017 Nov 17;8:2271. doi: 10.3389/fmicb.2017.02271. eCollection 2017.


Protective effects of compounds from Garcinia mangostana L. (mangosteen) against UVB damage in HaCaT cells and hairless mice.

Im AR, Kim YM, Chin YW, Chae S.

Int J Mol Med. 2017 Dec;40(6):1941-1949. doi: 10.3892/ijmm.2017.3188. Epub 2017 Oct 13.


Houttuynia cordata Facilitates Metformin on Ameliorating Insulin Resistance Associated with Gut Microbiota Alteration in OLETF Rats.

Wang JH, Bose S, Lim SK, Ansari A, Chin YW, Choi HS, Kim H.

Genes (Basel). 2017 Sep 22;8(10). pii: E239. doi: 10.3390/genes8100239.


In vivo therapeutic effect of combination treatment with metformin and Scutellaria baicalensis on maintaining bile acid homeostasis.

Han K, Bose S, Wang JH, Lim SK, Chin YW, Kim YM, Choi HS, Kim H.

PLoS One. 2017 Sep 6;12(9):e0182467. doi: 10.1371/journal.pone.0182467. eCollection 2017.


α, γ-Mangostins Induce Autophagy and Show Synergistic Effect with Gemcitabine in Pancreatic Cancer Cell Lines.

Kim M, Chin YW, Lee EJ.

Biomol Ther (Seoul). 2017 Nov 1;25(6):609-617. doi: 10.4062/biomolther.2017.074.


New Aromatic Compounds from the Fruiting Body of Sparassis crispa (Wulf.) and Their Inhibitory Activities on Proprotein Convertase Subtilisin/Kexin Type 9 mRNA Expression.

Bang S, Chae HS, Lee C, Choi HG, Ryu J, Li W, Lee H, Jeong GS, Chin YW, Shim SH.

J Agric Food Chem. 2017 Aug 2;65(30):6152-6157. doi: 10.1021/acs.jafc.7b02657. Epub 2017 Jul 20.


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