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Items: 1 to 20 of 209

1.

Cellular adaptation to hypoxia through hypoxia inducible factors and beyond.

Lee P, Chandel NS, Simon MC.

Nat Rev Mol Cell Biol. 2020 Mar 6. doi: 10.1038/s41580-020-0227-y. [Epub ahead of print] Review.

PMID:
32144406
2.

FIH-1 engages novel binding partners to positively influence epithelial proliferation via p63.

Kaplan N, Dong Y, Wang S, Yang W, Park JK, Wang J, Fiolek E, Perez White B, Chandel NS, Peng H, Lavker RM.

FASEB J. 2020 Jan;34(1):525-539. doi: 10.1096/fj.201901512R. Epub 2019 Nov 25.

PMID:
31914679
3.

Mitochondrial TCA cycle metabolites control physiology and disease.

Martínez-Reyes I, Chandel NS.

Nat Commun. 2020 Jan 3;11(1):102. doi: 10.1038/s41467-019-13668-3. Review.

4.

Essentiality of fatty acid synthase in the 2D to anchorage-independent growth transition in transforming cells.

Bueno MJ, Jimenez-Renard V, Samino S, Capellades J, Junza A, López-Rodríguez ML, Garcia-Carceles J, Lopez-Fabuel I, Bolaños JP, Chandel NS, Yanes O, Colomer R, Quintela-Fandino M.

Nat Commun. 2019 Nov 1;10(1):5011. doi: 10.1038/s41467-019-13028-1.

5.

Mitochondrial stress causes neuronal dysfunction via an ATF4-dependent increase in L-2-hydroxyglutarate.

Hunt RJ, Granat L, McElroy GS, Ranganathan R, Chandel NS, Bateman JM.

J Cell Biol. 2019 Dec 2;218(12):4007-4016. doi: 10.1083/jcb.201904148. Epub 2019 Oct 23.

6.

Requirement of Mitochondrial Transcription Factor A in Tissue-Resident Regulatory T Cell Maintenance and Function.

Fu Z, Ye J, Dean JW, Bostick JW, Weinberg SE, Xiong L, Oliff KN, Chen ZE, Avram D, Chandel NS, Zhou L.

Cell Rep. 2019 Jul 2;28(1):159-171.e4. doi: 10.1016/j.celrep.2019.06.024.

7.

Glucose Metabolism Linked to Antiviral Responses.

Stoolman JS, Chandel NS.

Cell. 2019 Jun 27;178(1):10-11. doi: 10.1016/j.cell.2019.05.057.

PMID:
31251910
8.

Mitochondrial complex III is necessary for endothelial cell proliferation during angiogenesis.

Diebold LP, Gil HJ, Gao P, Martinez CA, Weinberg SE, Chandel NS.

Nat Metab. 2019 Jan;1(1):158-171. doi: 10.1038/s42255-018-0011-x. Epub 2019 Jan 7.

9.

Suppressing Mitochondrial Respiration Is Critical for Hypoxia Tolerance in the Fetal Growth Plate.

Yao Q, Khan MP, Merceron C, LaGory EL, Tata Z, Mangiavini L, Hu J, Vemulapalli K, Chandel NS, Giaccia AJ, Schipani E.

Dev Cell. 2019 Jun 3;49(5):748-763.e7. doi: 10.1016/j.devcel.2019.04.029. Epub 2019 May 16.

PMID:
31105007
10.

Immunometabolism of pro-repair cells.

Singer BD, Chandel NS.

J Clin Invest. 2019 May 13;129(7):2597-2607. doi: 10.1172/JCI124613. eCollection 2019 May 13. Review.

11.

HIF-1α Is a Metabolic Switch between Glycolytic-Driven Migration and Oxidative Phosphorylation-Driven Immunosuppression of Tregs in Glioblastoma.

Miska J, Lee-Chang C, Rashidi A, Muroski ME, Chang AL, Lopez-Rosas A, Zhang P, Panek WK, Cordero A, Han Y, Ahmed AU, Chandel NS, Lesniak MS.

Cell Rep. 2019 Apr 2;27(1):226-237.e4. doi: 10.1016/j.celrep.2019.03.029.

12.

NAD-biosynthetic pathways regulate innate immunity.

Billingham LK, Chandel NS.

Nat Immunol. 2019 Apr;20(4):380-382. doi: 10.1038/s41590-019-0353-x. No abstract available.

PMID:
30858621
13.

Serine Metabolism Supports Macrophage IL-1β Production.

Rodriguez AE, Ducker GS, Billingham LK, Martinez CA, Mainolfi N, Suri V, Friedman A, Manfredi MG, Weinberg SE, Rabinowitz JD, Chandel NS.

Cell Metab. 2019 Apr 2;29(4):1003-1011.e4. doi: 10.1016/j.cmet.2019.01.014. Epub 2019 Feb 14.

PMID:
30773464
14.

Metformin Targets Mitochondrial Electron Transport to Reduce Air-Pollution-Induced Thrombosis.

Soberanes S, Misharin AV, Jairaman A, Morales-Nebreda L, McQuattie-Pimentel AC, Cho T, Hamanaka RB, Meliton AY, Reyfman PA, Walter JM, Chen CI, Chi M, Chiu S, Gonzalez-Gonzalez FJ, Antalek M, Abdala-Valencia H, Chiarella SE, Sun KA, Woods PS, Ghio AJ, Jain M, Perlman H, Ridge KM, Morimoto RI, Sznajder JI, Balch WE, Bhorade SM, Bharat A, Prakriya M, Chandel NS, Mutlu GM, Budinger GRS.

Cell Metab. 2019 Feb 5;29(2):503. doi: 10.1016/j.cmet.2018.12.001. No abstract available.

15.

The mitochondrial retrograde signaling regulates Wnt signaling to promote tumorigenesis in colon cancer.

Wen YA, Xiong X, Scott T, Li AT, Wang C, Weiss HL, Tan L, Bradford E, Fan TWM, Chandel NS, Barrett TA, Gao T.

Cell Death Differ. 2019 Oct;26(10):1955-1969. doi: 10.1038/s41418-018-0265-6. Epub 2019 Jan 18.

PMID:
30659235
16.

Mitochondrial complex III is essential for suppressive function of regulatory T cells.

Weinberg SE, Singer BD, Steinert EM, Martinez CA, Mehta MM, Martínez-Reyes I, Gao P, Helmin KA, Abdala-Valencia H, Sena LA, Schumacker PT, Turka LA, Chandel NS.

Nature. 2019 Jan;565(7740):495-499. doi: 10.1038/s41586-018-0846-z. Epub 2019 Jan 9.

17.

IDH3α regulates one-carbon metabolism in glioblastoma.

May JL, Kouri FM, Hurley LA, Liu J, Tommasini-Ghelfi S, Ji Y, Gao P, Calvert AE, Lee A, Chandel NS, Davuluri RV, Horbinski CM, Locasale JW, Stegh AH.

Sci Adv. 2019 Jan 2;5(1):eaat0456. doi: 10.1126/sciadv.aat0456. eCollection 2019 Jan.

18.

Efferocytosis Fuels Requirements of Fatty Acid Oxidation and the Electron Transport Chain to Polarize Macrophages for Tissue Repair.

Zhang S, Weinberg S, DeBerge M, Gainullina A, Schipma M, Kinchen JM, Ben-Sahra I, Gius DR, Yvan-Charvet L, Chandel NS, Schumacker PT, Thorp EB.

Cell Metab. 2019 Feb 5;29(2):443-456.e5. doi: 10.1016/j.cmet.2018.12.004. Epub 2018 Dec 27.

19.

Probing mitochondrial metabolism in vivo.

McElroy GS, Chandel NS.

Proc Natl Acad Sci U S A. 2019 Jan 2;116(1):20-22. doi: 10.1073/pnas.1819614116. Epub 2018 Dec 18. No abstract available.

20.

Hepatic HKDC1 Expression Contributes to Liver Metabolism.

Pusec CM, De Jesus A, Khan MW, Terry AR, Ludvik AE, Xu K, Giancola N, Pervaiz H, Daviau Smith E, Ding X, Harrison S, Chandel NS, Becker TC, Hay N, Ardehali H, Cordoba-Chacon J, Layden BT.

Endocrinology. 2019 Feb 1;160(2):313-330. doi: 10.1210/en.2018-00887.

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