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Items: 1 to 20 of 370

1.

Treating Alzheimer's disease by targeting iron.

Nikseresht S, Bush AI, Ayton S.

Br J Pharmacol. 2019 Jan 10. doi: 10.1111/bph.14567. [Epub ahead of print] Review.

PMID:
30632143
2.

Amyloid Precursor Protein Mediates Neuronal Protection from Rotenone Toxicity.

Cimdins K, Waugh HS, Chrysostomou V, Lopez Sanchez MIG, Johannsen VA, Cook MJ, Crowston JG, Hill AF, Duce JA, Bush AI, Trounce IA.

Mol Neurobiol. 2019 Jan 5. doi: 10.1007/s12035-018-1460-7. [Epub ahead of print]

PMID:
30612335
3.

Cerebrospinal fluid ferritin levels predict brain hypometabolism in people with underlying β-amyloid pathology.

Diouf I, Fazlollahi A, Bush AI, Ayton S; Alzheimer's disease Neuroimaging Initiative.

Neurobiol Dis. 2018 Dec 14;124:335-339. doi: 10.1016/j.nbd.2018.12.010. [Epub ahead of print]

PMID:
30557658
4.

Molecular Mechanisms of Glutaredoxin Enzymes: Versatile Hubs for Thiol-Disulfide Exchange between Protein Thiols and Glutathione.

Xiao Z, La Fontaine S, Bush AI, Wedd AG.

J Mol Biol. 2019 Jan 18;431(2):158-177. doi: 10.1016/j.jmb.2018.12.006. Epub 2018 Dec 12. Review.

PMID:
30552876
5.

Amyloid β1-42-Induced Rapid Zn2+ Influx into Dentate Granule Cells Attenuates Maintained LTP Followed by Retrograde Amnesia.

Tamano H, Suzuki H, Murakami T, Fujii H, Adlard PA, Bush AI, Takeda A.

Mol Neurobiol. 2018 Nov 20. doi: 10.1007/s12035-018-1429-6. [Epub ahead of print]

PMID:
30460616
6.

Parkinson's disease prevalence and the association with rurality and agricultural determinants.

Ayton D, Ayton S, Barker AL, Bush AI, Warren N.

Parkinsonism Relat Disord. 2018 Oct 23. pii: S1353-8020(18)30462-0. doi: 10.1016/j.parkreldis.2018.10.026. [Epub ahead of print]

PMID:
30377035
7.

Striking while the iron is hot: Iron metabolism and ferroptosis in neurodegeneration.

Masaldan S, Bush AI, Devos D, Rolland AS, Moreau C.

Free Radic Biol Med. 2018 Sep 25. pii: S0891-5849(18)31680-0. doi: 10.1016/j.freeradbiomed.2018.09.033. [Epub ahead of print]

PMID:
30266679
8.

Supranutritional Sodium Selenate Supplementation Delivers Selenium to the Central Nervous System: Results from a Randomized Controlled Pilot Trial in Alzheimer's Disease.

Cardoso BR, Roberts BR, Malpas CB, Vivash L, Genc S, Saling MM, Desmond P, Steward C, Hicks RJ, Callahan J, Brodtmann A, Collins S, Macfarlane S, Corcoran NM, Hovens CM, Velakoulis D, O'Brien TJ, Hare DJ, Bush AI.

Neurotherapeutics. 2018 Sep 13. doi: 10.1007/s13311-018-0662-z. [Epub ahead of print]

PMID:
30215171
9.

Targeting metals rescues the phenotype in an animal model of tauopathy.

Sedjahtera A, Gunawan L, Bray L, Hung LW, Parsons J, Okamura N, Villemagne VL, Yanai K, Liu XM, Chan J, Bush AI, Finkelstein DI, Barnham KJ, Cherny RA, Adlard PA.

Metallomics. 2018 Sep 19;10(9):1339-1347. doi: 10.1039/c8mt00153g.

PMID:
30168573
10.

Redox modulating factors impact longevity regulation in rotifers.

Macsai L, Olah Z, Bush AI, Galik B, Onody R, Kalman J, Datki Z.

J Gerontol A Biol Sci Med Sci. 2018 Aug 27. doi: 10.1093/gerona/gly193. [Epub ahead of print]

PMID:
30165673
11.

Manganese causes neurotoxic iron accumulation via translational repression of amyloid precursor protein and H-Ferritin.

Venkataramani V, Doeppner TR, Willkommen D, Cahill CM, Xin Y, Ye G, Liu Y, Southon A, Aron A, Au-Yeung HY, Huang X, Lahiri DK, Wang F, Bush AI, Wulf GG, Ströbel P, Michalke B, Rogers JT.

J Neurochem. 2018 Dec;147(6):831-848. doi: 10.1111/jnc.14580. Epub 2018 Nov 19.

PMID:
30152072
12.

Marked Age-Related Changes in Brain Iron Homeostasis in Amyloid Protein Precursor Knockout Mice.

Belaidi AA, Gunn AP, Wong BX, Ayton S, Appukuttan AT, Roberts BR, Duce JA, Bush AI.

Neurotherapeutics. 2018 Oct;15(4):1055-1062. doi: 10.1007/s13311-018-0656-x.

PMID:
30112699
13.

Overcoming the Blood-Brain Barrier: The Role of Nanomaterials in Treating Neurological Diseases.

Furtado D, Björnmalm M, Ayton S, Bush AI, Kempe K, Caruso F.

Adv Mater. 2018 Nov;30(46):e1801362. doi: 10.1002/adma.201801362. Epub 2018 Jul 31. Review.

PMID:
30066406
14.

Adrenergic β receptor activation in the basolateral amygdala, which is intracellular Zn2+-dependent, rescues amyloid β1-42-induced attenuation of dentate gyrus LTP.

Tamano H, Kubota M, Fujise Y, Shimaya R, Itoh R, Suzuki M, Adlard PA, Bush AI, Takeda A.

Neurochem Int. 2018 Nov;120:43-48. doi: 10.1016/j.neuint.2018.07.005. Epub 2018 Jul 17.

PMID:
30030113
15.

Mediator effects of parameters of inflammation and neurogenesis from a N-acetyl cysteine clinical-trial for bipolar depression.

Panizzutti B, Bortolasci C, Hasebe K, Kidnapillai S, Gray L, Walder K, Berk M, Mohebbi M, Dodd S, Gama C, Magalhães PV, Cotton SM, Kapczinski F, Bush AI, Malhi GS, Dean OM.

Acta Neuropsychiatr. 2018 Dec;30(6):334-341. doi: 10.1017/neu.2018.13. Epub 2018 Jul 16.

PMID:
30008280
16.

Ablation of tau causes an olfactory deficit in a murine model of Parkinson's disease.

Beauchamp LC, Chan J, Hung LW, Padman BS, Vella LJ, Liu XM, Coleman B, Bush AI, Lazarou M, Hill AF, Jacobson L, Barnham KJ.

Acta Neuropathol Commun. 2018 Jul 5;6(1):57. doi: 10.1186/s40478-018-0560-y.

17.

Association of metals with the risk and clinical characteristics of Parkinson's disease.

Kim MJ, Oh SB, Kim J, Kim K, Ryu HS, Kim MS, Ayton S, Bush AI, Lee JY, Chung SJ.

Parkinsonism Relat Disord. 2018 Oct;55:117-121. doi: 10.1016/j.parkreldis.2018.05.022. Epub 2018 May 28.

PMID:
29891430
18.

Iron and Alzheimer's Disease: An Update on Emerging Mechanisms.

Lane DJR, Ayton S, Bush AI.

J Alzheimers Dis. 2018;64(s1):S379-S395. doi: 10.3233/JAD-179944.

PMID:
29865061
19.

Glutaredoxins employ parallel monothiol-dithiol mechanisms to catalyze thiol-disulfide exchanges with protein disulfides.

Ukuwela AA, Bush AI, Wedd AG, Xiao Z.

Chem Sci. 2017 Dec 6;9(5):1173-1183. doi: 10.1039/c7sc04416j. eCollection 2018 Feb 7.

20.

Alzheimer's Disease: A Journey from Amyloid Peptides and Oxidative Stress, to Biomarker Technologies and Disease Prevention Strategies-Gains from AIBL and DIAN Cohort Studies.

Martins RN, Villemagne V, Sohrabi HR, Chatterjee P, Shah TM, Verdile G, Fraser P, Taddei K, Gupta VB, Rainey-Smith SR, Hone E, Pedrini S, Lim WL, Martins I, Frost S, Gupta S, O'Bryant S, Rembach A, Ames D, Ellis K, Fuller SJ, Brown B, Gardener SL, Fernando B, Bharadwaj P, Burnham S, Laws SM, Barron AM, Goozee K, Wahjoepramono EJ, Asih PR, Doecke JD, Salvado O, Bush AI, Rowe CC, Gandy SE, Masters CL.

J Alzheimers Dis. 2018;62(3):965-992. doi: 10.3233/JAD-171145.

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