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Items: 1 to 20 of 59


Programmable DNA cleavage by Ago nucleases from mesophilic bacteria Clostridium butyricum and Limnothrix rosea.

Kuzmenko A, Yudin D, Ryazansky S, Kulbachinskiy A, Aravin AA.

Nucleic Acids Res. 2019 Jun 20;47(11):5822-5836. doi: 10.1093/nar/gkz379.


piRNA silencing contributes to interspecies hybrid sterility and reproductive isolation in Drosophila melanogaster.

Kotov AA, Adashev VE, Godneeva BK, Ninova M, Shatskikh AS, Bazylev SS, Aravin AA, Olenina LV.

Nucleic Acids Res. 2019 May 7;47(8):4255-4271. doi: 10.1093/nar/gkz130.


The Expanded Universe of Prokaryotic Argonaute Proteins.

Ryazansky S, Kulbachinskiy A, Aravin AA.

MBio. 2018 Dec 18;9(6). pii: e01935-18. doi: 10.1128/mBio.01935-18.


DNA interference and beyond: structure and functions of prokaryotic Argonaute proteins.

Lisitskaya L, Aravin AA, Kulbachinskiy A.

Nat Commun. 2018 Dec 4;9(1):5165. doi: 10.1038/s41467-018-07449-7. Review.


Accommodation of Helical Imperfections in Rhodobacter sphaeroides Argonaute Ternary Complexes with Guide RNA and Target DNA.

Liu Y, Esyunina D, Olovnikov I, Teplova M, Kulbachinskiy A, Aravin AA, Patel DJ.

Cell Rep. 2018 Jul 10;24(2):453-462. doi: 10.1016/j.celrep.2018.06.021.


Argonaute Proteins and Mechanisms of RNA Interference in Eukaryotes and Prokaryotes.

Olina AV, Kulbachinskiy AV, Aravin AA, Esyunina DM.

Biochemistry (Mosc). 2018 May;83(5):483-497. doi: 10.1134/S0006297918050024. Review.


piRNA Biogenesis in Drosophila melanogaster.

Huang X, Fejes Tóth K, Aravin AA.

Trends Genet. 2017 Nov;33(11):882-894. doi: 10.1016/j.tig.2017.09.002. Epub 2017 Sep 27. Review.


Cutoff Suppresses RNA Polymerase II Termination to Ensure Expression of piRNA Precursors.

Chen YA, Stuwe E, Luo Y, Ninova M, Le Thomas A, Rozhavskaya E, Li S, Vempati S, Laver JD, Patel DJ, Smibert CA, Lipshitz HD, Toth KF, Aravin AA.

Mol Cell. 2016 Jul 7;63(1):97-109. doi: 10.1016/j.molcel.2016.05.010. Epub 2016 Jun 9.


Splicing-independent loading of TREX on nascent RNA is required for efficient expression of dual-strand piRNA clusters in Drosophila.

Hur JK, Luo Y, Moon S, Ninova M, Marinov GK, Chung YD, Aravin AA.

Genes Dev. 2016 Apr 1;30(7):840-55. doi: 10.1101/gad.276030.115.


Aub and Ago3 Are Recruited to Nuage through Two Mechanisms to Form a Ping-Pong Complex Assembled by Krimper.

Webster A, Li S, Hur JK, Wachsmuth M, Bois JS, Perkins EM, Patel DJ, Aravin AA.

Mol Cell. 2015 Aug 20;59(4):564-75. doi: 10.1016/j.molcel.2015.07.017.


MIWI2 and MILI Have Differential Effects on piRNA Biogenesis and DNA Methylation.

Manakov SA, Pezic D, Marinov GK, Pastor WA, Sachidanandam R, Aravin AA.

Cell Rep. 2015 Aug 25;12(8):1234-43. doi: 10.1016/j.celrep.2015.07.036. Epub 2015 Aug 13.


Erratum: MORC1 represses transposable elements in the mouse male germline.

Pastor WA, Stroud H, Nee K, Liu W, Pezic D, Manakov S, Lee SA, Moissiard G, Zamudio N, Bourc'his D, Aravin AA, Clark AT, Jacobsen SE.

Nat Commun. 2015 Jul 10;6:7604. doi: 10.1038/ncomms8604. No abstract available.


Pitfalls of mapping high-throughput sequencing data to repetitive sequences: Piwi's genomic targets still not identified.

Marinov GK, Wang J, Handler D, Wold BJ, Weng Z, Hannon GJ, Aravin AA, Zamore PD, Brennecke J, Toth KF.

Dev Cell. 2015 Mar 23;32(6):765-71. doi: 10.1016/j.devcel.2015.01.013.


MORC1 represses transposable elements in the mouse male germline.

Pastor WA, Stroud H, Nee K, Liu W, Pezic D, Manakov S, Lee SA, Moissiard G, Zamudio N, Bourc'his D, Aravin AA, Clark AT, Jacobsen SE.

Nat Commun. 2014 Dec 12;5:5795. doi: 10.1038/ncomms6795. Erratum in: Nat Commun. 2015;6:7604.


A transgenerational process defines piRNA biogenesis in Drosophila virilis.

Le Thomas A, Marinov GK, Aravin AA.

Cell Rep. 2014 Sep 25;8(6):1617-1623. doi: 10.1016/j.celrep.2014.08.013. Epub 2014 Sep 4.


Transgenerationally inherited piRNAs trigger piRNA biogenesis by changing the chromatin of piRNA clusters and inducing precursor processing.

Le Thomas A, Stuwe E, Li S, Du J, Marinov G, Rozhkov N, Chen YC, Luo Y, Sachidanandam R, Toth KF, Patel D, Aravin AA.

Genes Dev. 2014 Aug 1;28(15):1667-80. doi: 10.1101/gad.245514.114.


Two waves of de novo methylation during mouse germ cell development.

Molaro A, Falciatori I, Hodges E, Aravin AA, Marran K, Rafii S, McCombie WR, Smith AD, Hannon GJ.

Genes Dev. 2014 Jul 15;28(14):1544-9. doi: 10.1101/gad.244350.114.


piRNA pathway targets active LINE1 elements to establish the repressive H3K9me3 mark in germ cells.

Pezic D, Manakov SA, Sachidanandam R, Aravin AA.

Genes Dev. 2014 Jul 1;28(13):1410-28. doi: 10.1101/gad.240895.114. Epub 2014 Jun 17.


Prokaryotic Argonautes defend genomes against invasive DNA.

Hur JK, Olovnikov I, Aravin AA.

Trends Biochem Sci. 2014 Jun;39(6):257-9. doi: 10.1016/j.tibs.2014.04.006. Epub 2014 May 13.

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