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Items: 1 to 20 of 606


Cancer drug development: The missing links.

Kunnumakkara AB, Bordoloi D, Sailo BL, Roy NK, Thakur KK, Banik K, Shakibaei M, Gupta SC, Aggarwal BB.

Exp Biol Med (Maywood). 2019 May;244(8):663-689. doi: 10.1177/1535370219839163. Epub 2019 Apr 8.


Induction of the Epithelial-to-Mesenchymal Transition of Human Colorectal Cancer by Human TNF-β (Lymphotoxin) and its Reversal by Resveratrol.

Buhrmann C, Yazdi M, Popper B, Kunnumakkara AB, Aggarwal BB, Shakibaei M.

Nutrients. 2019 Mar 26;11(3). pii: E704. doi: 10.3390/nu11030704.


Correction: Celastrol Suppresses Angiogenesis-Mediated Tumor Growth through Inhibition of AKT/Mammalian Target of Rapamycin Pathway.

Pang X, Yi Z, Zhang J, Lu B, Sung B, Qu W, Aggarwal BB, Liu M.

Cancer Res. 2019 Feb 1;79(3):685. doi: 10.1158/0008-5472.CAN-18-3859. No abstract available.


Evidence that TNF-β induces proliferation in colorectal cancer cells and resveratrol can down-modulate it.

Buhrmann C, Yazdi M, Popper B, Shayan P, Goel A, Aggarwal BB, Shakibaei M.

Exp Biol Med (Maywood). 2019 Jan;244(1):1-12. doi: 10.1177/1535370218824538. Epub 2019 Jan 19.


Inflammation, a Double-Edge Sword for Cancer and Other Age-Related Diseases.

Gupta SC, Kunnumakkara AB, Aggarwal S, Aggarwal BB.

Front Immunol. 2018 Sep 27;9:2160. doi: 10.3389/fimmu.2018.02160. eCollection 2018. Review.


Googling the Guggul (Commiphora and Boswellia) for Prevention of Chronic Diseases.

Kunnumakkara AB, Banik K, Bordoloi D, Harsha C, Sailo BL, Padmavathi G, Roy NK, Gupta SC, Aggarwal BB.

Front Pharmacol. 2018 Aug 6;9:686. doi: 10.3389/fphar.2018.00686. eCollection 2018. Review.


Resveratrol Chemosensitizes TNF-β-Induced Survival of 5-FU-Treated Colorectal Cancer Cells.

Buhrmann C, Yazdi M, Popper B, Shayan P, Goel A, Aggarwal BB, Shakibaei M.

Nutrients. 2018 Jul 12;10(7). pii: E888. doi: 10.3390/nu10070888.


Dietary nutraceuticals as backbone for bone health.

Pandey MK, Gupta SC, Karelia D, Gilhooley PJ, Shakibaei M, Aggarwal BB.

Biotechnol Adv. 2018 Nov 1;36(6):1633-1648. doi: 10.1016/j.biotechadv.2018.03.014. Epub 2018 Mar 27. Review.


Chronic diseases, inflammation, and spices: how are they linked?

Kunnumakkara AB, Sailo BL, Banik K, Harsha C, Prasad S, Gupta SC, Bharti AC, Aggarwal BB.

J Transl Med. 2018 Jan 25;16(1):14. doi: 10.1186/s12967-018-1381-2. Review.


Curcumin-Free Turmeric Exhibits Activity against Human HCT-116 Colon Tumor Xenograft: Comparison with Curcumin and Whole Turmeric.

Prasad S, Tyagi AK, Siddik ZH, Aggarwal BB.

Front Pharmacol. 2017 Dec 12;8:871. doi: 10.3389/fphar.2017.00871. eCollection 2017. Retraction in: Front Pharmacol. 2018 Apr 16;9:400.


Resveratrol downregulates inflammatory pathway activated by lymphotoxin α (TNF-β) in articular chondrocytes: Comparison with TNF-α.

Buhrmann C, Popper B, Aggarwal BB, Shakibaei M.

PLoS One. 2017 Nov 2;12(11):e0186993. doi: 10.1371/journal.pone.0186993. eCollection 2017.


Food Antioxidants and Their Anti-Inflammatory Properties: A Potential Role in Cardiovascular Diseases and Cancer Prevention.

Griffiths K, Aggarwal BB, Singh RB, Buttar HS, Wilson D, De Meester F.

Diseases. 2016 Aug 1;4(3). pii: E28. doi: 10.3390/diseases4030028. Review.


Calebin A, a novel component of turmeric, suppresses NF-κB regulated cell survival and inflammatory gene products leading to inhibition of cell growth and chemosensitization.

Tyagi AK, Prasad S, Majeed M, Aggarwal BB.

Phytomedicine. 2017 Oct 15;34:171-181. doi: 10.1016/j.phymed.2017.08.021. Epub 2017 Aug 31.


Neem (Azadirachta indica): An indian traditional panacea with modern molecular basis.

Gupta SC, Prasad S, Tyagi AK, Kunnumakkara AB, Aggarwal BB.

Phytomedicine. 2017 Oct 15;34:14-20. doi: 10.1016/j.phymed.2017.07.001. Epub 2017 Jul 3. Review.


Regulation of cell signaling pathways by dietary agents for cancer prevention and treatment.

Pandey MK, Gupta SC, Nabavizadeh A, Aggarwal BB.

Semin Cancer Biol. 2017 Oct;46:158-181. doi: 10.1016/j.semcancer.2017.07.002. Epub 2017 Aug 16. Review.


Curcumin mediates anticancer effects by modulating multiple cell signaling pathways.

Kunnumakkara AB, Bordoloi D, Harsha C, Banik K, Gupta SC, Aggarwal BB.

Clin Sci (Lond). 2017 Jul 5;131(15):1781-1799. doi: 10.1042/CS20160935. Print 2017 Aug 1. Review.


Curcumin, the golden nutraceutical: multitargeting for multiple chronic diseases.

Kunnumakkara AB, Bordoloi D, Padmavathi G, Monisha J, Roy NK, Prasad S, Aggarwal BB.

Br J Pharmacol. 2017 Jun;174(11):1325-1348. doi: 10.1111/bph.13621. Epub 2016 Oct 21. Review.


Prevention and Treatment of Cancer: Hypes and Hopes 6th International Translational Cancer Research Conference.

Patel P, Vora H, Aggarwal BB, Gandhi V, Mehta K, Pathak S.

Anticancer Res. 2016 Sep;36(9):4971-5.


γ-Tocotrienol suppresses growth and sensitises human colorectal tumours to capecitabine in a nude mouse xenograft model by down-regulating multiple molecules.

Prasad S, Gupta SC, Tyagi AK, Aggarwal BB.

Br J Cancer. 2016 Sep 27;115(7):814-24. doi: 10.1038/bjc.2016.257. Epub 2016 Aug 30.


3-Formylchromone interacts with cysteine 38 in p65 protein and with cysteine 179 in IκBα kinase, leading to down-regulation of nuclear factor-κB (NF-κB)-regulated gene products and sensitization of tumor cells.

Yadav VR, Prasad S, Gupta SC, Sung B, Phatak SS, Zhang S, Aggarwal BB.

J Biol Chem. 2016 Aug 5;291(32):16926. doi: 10.1074/jbc.A111.274613. No abstract available.

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