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Items: 1 to 20 of 26


Interstitial telomeric loops and implications of the interaction between TRF2 and lamin A/C.

Smith ED, Garza-Gongora AG, MacQuarrie KL, Kosak ST.

Differentiation. 2018 Jul - Aug;102:19-26. doi: 10.1016/j.diff.2018.06.001. Epub 2018 Jun 18. Review.


Coils spring into action: Cajal bodies and the genomic organization of transcription (comment DOI 10.1002/bies.201600144).

Fanslow D, Kosak ST.

Bioessays. 2016 Dec;38(12):1190. doi: 10.1002/bies.201600232. Epub 2016 Nov 17. No abstract available.


Persistent nuclear actin filaments inhibit transcription by RNA polymerase II.

Serebryannyy LA, Parilla M, Annibale P, Cruz CM, Laster K, Gratton E, Kudryashov D, Kosak ST, Gottardi CJ, de Lanerolle P.

J Cell Sci. 2016 Sep 15;129(18):3412-25. doi: 10.1242/jcs.195867. Epub 2016 Aug 2.


Topologically associated domains enriched for lineage-specific genes reveal expression-dependent nuclear topologies during myogenesis.

Neems DS, Garza-Gongora AG, Smith ED, Kosak ST.

Proc Natl Acad Sci U S A. 2016 Mar 22;113(12):E1691-700. doi: 10.1073/pnas.1521826113. Epub 2016 Mar 8.


Differential contribution of cis-regulatory elements to higher order chromatin structure and expression of the CFTR locus.

Yang R, Kerschner JL, Gosalia N, Neems D, Gorsic LK, Safi A, Crawford GE, Kosak ST, Leir SH, Harris A.

Nucleic Acids Res. 2016 Apr 20;44(7):3082-94. doi: 10.1093/nar/gkv1358. Epub 2015 Dec 15.


A beginning of the end: new insights into the functional organization of telomeres.

Wood AM, Laster K, Rice EL, Kosak ST.

Nucleus. 2015;6(3):172-8. doi: 10.1080/19491034.2015.1048407.


TRF2 and lamin A/C interact to facilitate the functional organization of chromosome ends.

Wood AM, Rendtlew Danielsen JM, Lucas CA, Rice EL, Scalzo D, Shimi T, Goldman RD, Smith ED, Le Beau MM, Kosak ST.

Nat Commun. 2014 Nov 17;5:5467. doi: 10.1038/ncomms6467.


Architectural proteins CTCF and cohesin have distinct roles in modulating the higher order structure and expression of the CFTR locus.

Gosalia N, Neems D, Kerschner JL, Kosak ST, Harris A.

Nucleic Acids Res. 2014 Sep;42(15):9612-22. doi: 10.1093/nar/gku648. Epub 2014 Jul 31.


α-Catenin is an inhibitor of transcription.

Daugherty RL, Serebryannyy L, Yemelyanov A, Flozak AS, Yu HJ, Kosak ST, deLanerolle P, Gottardi CJ.

Proc Natl Acad Sci U S A. 2014 Apr 8;111(14):5260-5. doi: 10.1073/pnas.1308663111. Epub 2014 Mar 25.


A Crowdsourced nucleus: understanding nuclear organization in terms of dynamically networked protein function.

Wood AM, Garza-Gongora AG, Kosak ST.

Biochim Biophys Acta. 2014 Mar;1839(3):178-90. doi: 10.1016/j.bbagrm.2014.01.003. Epub 2014 Jan 9. Review.


Characterization of a large human transgene following invasin-mediated delivery in a bacterial artificial chromosome.

Gillen AE, Lucas CA, Haussecker PL, Kosak ST, Harris A.

Chromosoma. 2013 Oct;122(5):351-61. doi: 10.1007/s00412-013-0418-9. Epub 2013 Jun 9.


The role of nuclear lamin B1 in cell proliferation and senescence.

Shimi T, Butin-Israeli V, Adam SA, Hamanaka RB, Goldman AE, Lucas CA, Shumaker DK, Kosak ST, Chandel NS, Goldman RD.

Genes Dev. 2011 Dec 15;25(24):2579-93. doi: 10.1101/gad.179515.111. Epub 2011 Dec 8.


A model of early human embryonic stem cell differentiation reveals inter- and intracellular changes on transition to squamous epithelium.

Galat V, Malchenko S, Galat Y, Ishkin A, Nikolsky Y, Kosak ST, Soares BM, Iannaccone P, Crispino JD, Hendrix MJ.

Stem Cells Dev. 2012 May 20;21(8):1250-63. doi: 10.1089/scd.2010.0578. Epub 2011 Oct 19.


Turning down the volume on transcriptional noise.

Neems D, Kosak ST.

Nat Cell Biol. 2010 Oct;12(10):929-31. doi: 10.1038/ncb1010-929.


Networking the nucleus.

Rajapakse I, Scalzo D, Tapscott SJ, Kosak ST, Groudine M.

Mol Syst Biol. 2010 Jul;6:395. doi: 10.1038/msb.2010.48. Review.


Genomic Pangea: coordinate gene regulation and cell-specific chromosomal topologies.

Laster K, Kosak ST.

Curr Opin Cell Biol. 2010 Jun;22(3):314-9. doi: 10.1016/ Epub 2010 May 22.


The emergence of lineage-specific chromosomal topologies from coordinate gene regulation.

Rajapakse I, Perlman MD, Scalzo D, Kooperberg C, Groudine M, Kosak ST.

Proc Natl Acad Sci U S A. 2009 Apr 21;106(16):6679-84. doi: 10.1073/pnas.0900986106. Epub 2009 Mar 10.


Coordinate gene regulation during hematopoiesis is related to genomic organization.

Kosak ST, Scalzo D, Alworth SV, Li F, Palmer S, Enver T, Lee JS, Groudine M.

PLoS Biol. 2007 Nov;5(11):e309.


Gene order and dynamic domains.

Kosak ST, Groudine M.

Science. 2004 Oct 22;306(5696):644-7.


Form follows function: The genomic organization of cellular differentiation.

Kosak ST, Groudine M.

Genes Dev. 2004 Jun 15;18(12):1371-84. Review.

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