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Items: 1 to 20 of 309

1.

Hypothalamic Leptin Gene Therapy Reduces Bone Marrow Adiposity in ob/ob Mice Fed Regular and High-Fat Diets.

Lindenmaier LB, Philbrick KA, Branscum AJ, Kalra SP, Turner RT, Iwaniec UT.

Front Endocrinol (Lausanne). 2016 Aug 16;7:110. doi: 10.3389/fendo.2016.00110. eCollection 2016.

2.

Hypothalamic leptin gene therapy reduces body weight without accelerating age-related bone loss.

Turner RT, Dube M, Branscum AJ, Wong CP, Olson DA, Zhong X, Kweh MF, Larkin IV, Wronski TJ, Rosen CJ, Kalra SP, Iwaniec UT.

J Endocrinol. 2015 Dec;227(3):129-41. doi: 10.1530/JOE-15-0280. Epub 2015 Oct 20.

3.

Should leptin replace insulin as a lifetime monotherapy for diabetes type 1 and 2?

Kalra SP.

Indian J Endocrinol Metab. 2013 Oct;17(Suppl 1):S23-4. doi: 10.4103/2230-8210.119496. Review.

4.

A case for new therapy for diabetes, is it leptin?

Kalra SP.

Indian J Endocrinol Metab. 2012 Dec;16(Suppl 3):S525-8. doi: 10.4103/2230-8210.105566. No abstract available.

5.

Peripheral leptin regulates bone formation.

Turner RT, Kalra SP, Wong CP, Philbrick KA, Lindenmaier LB, Boghossian S, Iwaniec UT.

J Bone Miner Res. 2013 Jan;28(1):22-34. doi: 10.1002/jbmr.1734.

6.

Effects of increased hypothalamic leptin gene expression on ovariectomy-induced bone loss in rats.

Jackson MA, Iwaniec UT, Turner RT, Wronski TJ, Kalra SP.

Peptides. 2011 Aug;32(8):1575-80. doi: 10.1016/j.peptides.2011.04.029. Epub 2011 May 27.

7.

Hypothalamic leptin gene therapy prevents weight gain without long-term detrimental effects on bone in growing and skeletally mature female rats.

Iwaniec UT, Boghossian S, Trevisiol CH, Wronski TJ, Turner RT, Kalra SP.

J Bone Miner Res. 2011 Jul;26(7):1506-16. doi: 10.1002/jbmr.365.

8.

Pivotal role of leptin-hypothalamus signaling in the etiology of diabetes uncovered by gene therapy: a new therapeutic intervention?

Kalra SP.

Gene Ther. 2011 Apr;18(4):319-25. doi: 10.1038/gt.2010.164. Epub 2011 Jan 6. Review.

PMID:
21209624
9.

Neuroendocrine control of energy homeostasis: update on new insights.

Kalra SP, Kalra PS.

Prog Brain Res. 2010;181:17-33. doi: 10.1016/S0079-6123(08)81002-3. Review.

PMID:
20478430
10.
11.

Leptin increases osteoblast-specific osteocalcin release through a hypothalamic relay.

Kalra SP, Dube MG, Iwaniec UT.

Peptides. 2009 May;30(5):967-73. doi: 10.1016/j.peptides.2009.01.020. Epub 2009 Feb 7.

12.

Central leptin gene therapy, a substitute for insulin therapy to ameliorate hyperglycemia and hyperphagia, and promote survival in insulin-deficient diabetic mice.

Kojima S, Asakawa A, Amitani H, Sakoguchi T, Ueno N, Inui A, Kalra SP.

Peptides. 2009 May;30(5):962-6. doi: 10.1016/j.peptides.2009.01.007. Epub 2009 Jan 22.

PMID:
19428774
13.

Body mass influences cortical bone mass independent of leptin signaling.

Iwaniec UT, Dube MG, Boghossian S, Song H, Helferich WG, Turner RT, Kalra SP.

Bone. 2009 Mar;44(3):404-12. doi: 10.1016/j.bone.2008.10.058. Epub 2008 Nov 27.

14.

Inhibition of p66ShcA redox activity in cardiac muscle cells attenuates hyperglycemia-induced oxidative stress and apoptosis.

Malhotra A, Vashistha H, Yadav VS, Dube MG, Kalra SP, Abdellatif M, Meggs LG.

Am J Physiol Heart Circ Physiol. 2009 Feb;296(2):H380-8. doi: 10.1152/ajpheart.00225.2008. Epub 2008 Dec 5.

15.
16.

Increased leptin expression selectively in the hypothalamus suppresses inflammatory markers CRP and IL-6 in leptin-deficient diabetic obese mice.

Dube MG, Torto R, Kalra SP.

Peptides. 2008 Apr;29(4):593-8. doi: 10.1016/j.peptides.2008.01.001. Epub 2008 Jan 17.

18.
19.

Central leptin gene therapy corrects skeletal abnormalities in leptin-deficient ob/ob mice.

Iwaniec UT, Boghossian S, Lapke PD, Turner RT, Kalra SP.

Peptides. 2007 May;28(5):1012-9. Epub 2007 Feb 12.

20.

Neuroendocrine actions and regulation of hypothalamic neuropeptide Y during lactation.

Crowley WR, Ramoz G, Torto R, Keefe KA, Wang JJ, Kalra SP.

Peptides. 2007 Feb;28(2):447-52. Epub 2007 Jan 22. Review.

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