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Items: 1 to 20 of 78

1.

Targeting Protein Tyrosine Phosphatase PTP-PEST for Therapeutic Intervention in Acute Myocardial Infarction.

Yang CF, Chen YY, Singh JP, Hsu SF, Liu YW, Yang CY, Chang CW, Chen SN, Shih RH, Hsu SD, Jou YS, Cheng CF, Meng TC.

Cardiovasc Res. 2019 Jun 22. pii: cvz165. doi: 10.1093/cvr/cvz165. [Epub ahead of print]

PMID:
31228185
2.

Untying a Knotted SPOUT RNA Methyltransferase by Circular Permutation Results in a Domain-Swapped Dimer.

Ko KT, Hu IC, Huang KF, Lyu PC, Hsu SD.

Structure. 2019 Aug 6;27(8):1224-1233.e4. doi: 10.1016/j.str.2019.04.004. Epub 2019 May 16.

PMID:
31104814
3.

Untying a Protein Knot by Circular Permutation.

Chuang YC, Hu IC, Lyu PC, Hsu SD.

J Mol Biol. 2019 Feb 15;431(4):857-863. doi: 10.1016/j.jmb.2019.01.005. Epub 2019 Jan 9.

PMID:
30639189
4.

Soluble Siglec-14 glycan-recognition protein is generated by alternative splicing and suppresses myeloid inflammatory responses.

Huang PJ, Low PY, Wang I, Hsu SD, Angata T.

J Biol Chem. 2018 Dec 21;293(51):19645-19658. doi: 10.1074/jbc.RA118.005676. Epub 2018 Oct 30.

PMID:
30377253
5.

Comparative folding analyses of unknotted versus trefoil-knotted ornithine transcarbamylases suggest stabilizing effects of protein knots.

Sriramoju MK, Yang TJ, Hsu SD.

Biochem Biophys Res Commun. 2018 Sep 5;503(2):822-829. doi: 10.1016/j.bbrc.2018.06.082. Epub 2018 Jun 21.

PMID:
29920242
6.

How Native and Non-Native Cations Bind and Modulate the Properties of GTP/ATP.

Dudev T, Grauffel C, Hsu SD, Lim C.

J Chem Theory Comput. 2018 Jun 12;14(6):3311-3320. doi: 10.1021/acs.jctc.8b00259. Epub 2018 May 30.

PMID:
29768917
7.

Topologically knotted deubiquitinases exhibit unprecedented mechanostability to withstand the proteolysis by an AAA+ protease.

Sriramoju MK, Chen Y, Lee YC, Hsu SD.

Sci Rep. 2018 May 4;8(1):7076. doi: 10.1038/s41598-018-25470-0.

8.

A Natively Monomeric Deubiquitinase UCH-L1 Forms Highly Dynamic but Defined Metastable Oligomeric Folding Intermediates.

Lee YC, Hsu SD.

J Phys Chem Lett. 2018 May 3;9(9):2433-2437. doi: 10.1021/acs.jpclett.8b00815. Epub 2018 Apr 25.

PMID:
29688017
9.

Dissecting the Structure-Activity Relationship of Galectin-Ligand Interactions.

Chan YC, Lin HY, Tu Z, Kuo YH, Hsu SD, Lin CH.

Int J Mol Sci. 2018 Jan 29;19(2). pii: E392. doi: 10.3390/ijms19020392. Review.

10.

Lactose Binding Induces Opposing Dynamics Changes in Human Galectins Revealed by NMR-Based Hydrogen-Deuterium Exchange.

Chien CH, Ho MR, Lin CH, Hsu SD.

Molecules. 2017 Aug 16;22(8). pii: E1357. doi: 10.3390/molecules22081357.

11.
12.

Protein knotting through concatenation significantly reduces folding stability.

Hsu SD.

Sci Rep. 2016 Dec 16;6:39357. doi: 10.1038/srep39357.

13.

Folding analysis of the most complex Stevedore's protein knot.

Wang I, Chen SY, Hsu ST.

Sci Rep. 2016 Aug 16;6:31514. doi: 10.1038/srep31514.

14.

Dual thio-digalactoside-binding modes of human galectins as the structural basis for the design of potent and selective inhibitors.

Hsieh TJ, Lin HY, Tu Z, Lin TC, Wu SC, Tseng YY, Liu FT, Hsu ST, Lin CH.

Sci Rep. 2016 Jul 15;6:29457. doi: 10.1038/srep29457.

15.

The Knotted Protein UCH-L1 Exhibits Partially Unfolded Forms under Native Conditions that Share Common Structural Features with Its Kinetic Folding Intermediates.

Lou SC, Wetzel S, Zhang H, Crone EW, Lee YT, Jackson SE, Hsu SD.

J Mol Biol. 2016 Jun 5;428(11):2507-2520. doi: 10.1016/j.jmb.2016.04.002. Epub 2016 Apr 8.

PMID:
27067109
16.

A Multivalent Marine Lectin from Crenomytilus grayanus Possesses Anti-cancer Activity through Recognizing Globotriose Gb3.

Liao JH, Chien CT, Wu HY, Huang KF, Wang I, Ho MR, Tu IF, Lee IM, Li W, Shih YL, Wu CY, Lukyanov PA, Hsu ST, Wu SH.

J Am Chem Soc. 2016 Apr 13;138(14):4787-95. doi: 10.1021/jacs.6b00111. Epub 2016 Apr 1.

PMID:
27010847
17.

A novel transition pathway of ligand-induced topological conversion from hybrid forms to parallel forms of human telomeric G-quadruplexes.

Wang ZF, Li MH, Chen WW, Hsu ST, Chang TC.

Nucleic Acids Res. 2016 May 5;44(8):3958-68. doi: 10.1093/nar/gkw145. Epub 2016 Mar 14.

18.

Moenomycin Biosynthesis: Structure and Mechanism of Action of the Prenyltransferase MoeN5.

Zhang L, Chen CC, Ko TP, Huang JW, Zheng Y, Liu W, Wang I, Malwal SR, Feng X, Wang K, Huang CH, Hsu ST, Wang AH, Oldfield E, Guo RT.

Angew Chem Int Ed Engl. 2016 Apr 4;55(15):4716-20. doi: 10.1002/anie.201511388. Epub 2016 Mar 8.

19.

Structures of Trypanosome Vacuolar Soluble Pyrophosphatases: Antiparasitic Drug Targets.

Yang Y, Ko TP, Chen CC, Huang G, Zheng Y, Liu W, Wang I, Ho MR, Hsu ST, O'Dowd B, Huff HC, Huang CH, Docampo R, Oldfield E, Guo RT.

ACS Chem Biol. 2016 May 20;11(5):1362-71. doi: 10.1021/acschembio.5b00724. Epub 2016 Mar 4.

20.

Familial Mutations and Post-translational Modifications of UCH-L1 in Parkinson's Disease and Neurodegenerative Disorders.

Lee YC, Hsu SD.

Curr Protein Pept Sci. 2017;18(7):733-745. doi: 10.2174/1389203717666160217143721. Review.

PMID:
26899237

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