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Items: 1 to 20 of 452


Bone marrow mesenchymal stem cells protect against n-hexane-induced neuropathy through beclin 1-independent inhibition of autophagy.

Hao J, Li S, Shi X, Qian Z, Sun Y, Wang D, Zhou X, Qu H, Hu S, Zuo E, Zhang C, Hou L, Wang Q, Piao F.

Sci Rep. 2018 Mar 14;8(1):4516. doi: 10.1038/s41598-018-22857-x.


Hypnotic Effect of Portulaca oleracea L on Pentobarbital-Induced Sleep in Mice.

Hamedi S, Forouzanfar F, Rakhshandeh H, Arian A.

Curr Drug Discov Technol. 2018 Mar 8. doi: 10.2174/1570163815666180308142543. [Epub ahead of print]


Piper sarmentosum Roxb. confers neuroprotection on beta-amyloid (Aβ)-induced microglia-mediated neuroinflammation and attenuates tau hyperphosphorylation in SH-SY5Y cells.

Yeo ETY, Wong KWL, See ML, Wong KY, Gan SY, Chan EWL.

J Ethnopharmacol. 2018 May 10;217:187-194. doi: 10.1016/j.jep.2018.02.025. Epub 2018 Feb 17.


2,5-Hexanedione induces dopaminergic neurodegeneration through integrin αMβ2/NADPH oxidase axis-mediated microglial activation.

Zhang C, Hou L, Yang J, Che Y, Sun F, Li H, Wang Q.

Cell Death Dis. 2018 Jan 19;9(2):60. doi: 10.1038/s41419-017-0091-7.


2,5-hexanedione induces bone marrow mesenchymal stem cell apoptosis via inhibition of Akt/Bad signal pathway.

Sun J, Shi X, Li S, Piao F.

J Cell Biochem. 2018 Apr;119(4):3732-3743. doi: 10.1002/jcb.26602. Epub 2018 Jan 11.


Bioassay-guided Isolation of Neuroprotective Fatty Acids from <i>Nigella sativa</i> against 1-methyl-4-phenylpyridinium-induced Neurotoxicity.

Hosseinzadeh L, Monaghash H, Ahmadi F, Ghiasvand N, Shokoohinia Y.

Pharmacogn Mag. 2017 Oct-Dec;13(52):627-633. doi: 10.4103/pm.pm_470_16. Epub 2017 Nov 13.


2,5-Hexanedione induces autophagic death of VSC4.1 cells via a PI3K/Akt/mTOR pathway.

Guan H, Piao H, Qian Z, Zhou X, Sun Y, Gao C, Li S, Piao F.

Mol Biosyst. 2017 Sep 26;13(10):1993-2005. doi: 10.1039/c7mb00001d.


Amburana cearensis seed extract protects brain mitochondria from oxidative stress and cerebellar cells from excitotoxicity induced by glutamate.

Lima Pereira ÉP, Santos Souza C, Amparo J, Short Ferreira R, Nuñez-Figueredo Y, Gonzaga Fernandez L, Ribeiro PR, Braga-de-Souza S, Amaral da Silva VD, Lima Costa S.

J Ethnopharmacol. 2017 Sep 14;209:157-166. doi: 10.1016/j.jep.2017.07.017. Epub 2017 Jul 14.


2,5-hexanedione downregulates nerve growth factor and induces neuron apoptosis in the spinal cord of rats via inhibition of the PI3K/Akt signaling pathway.

Wang Z, Qiu Z, Gao C, Sun Y, Dong W, Zhang Y, Chen R, Qi Y, Li S, Guo Y, Piao Y, Li S, Piao F.

PLoS One. 2017 Jun 27;12(6):e0179388. doi: 10.1371/journal.pone.0179388. eCollection 2017.


n-Hexane intoxication in a Chinese medicine pharmaceutical plant: a case report.

Pan JH, Peng CY, Lo CT, Dai CY, Wang CL, Chuang HY.

J Med Case Rep. 2017 Apr 28;11(1):120. doi: 10.1186/s13256-017-1280-9.


Preclinical predictors that the orthosteric mGlu2/3 receptor antagonist LY3020371 will not engender ketamine-associated neurotoxic, motor, cognitive, subjective, or abuse-liability-related effects.

Witkin JM, Monn JA, Li J, Johnson B, McKinzie DL, Wang XS, Heinz BA, Li R, Ornstein PL, Smith SC, Mitch CH, Calligaro DO, Swanson S, Allen D, Phillips K, Gilmour G.

Pharmacol Biochem Behav. 2017 Apr;155:43-55. doi: 10.1016/j.pbb.2017.03.001. Epub 2017 Mar 8.


Using early life stages of marine animals to screen the toxicity of priority hazardous and noxious substances.

Cunha I, Torres T, Oliveira H, Martins R, McGowan T, Sheahan D, Santos MM.

Environ Sci Pollut Res Int. 2017 Apr;24(11):10510-10518. doi: 10.1007/s11356-017-8663-8. Epub 2017 Mar 10.


Diallyl trisulfide attenuated n-hexane induced neurotoxicity in rats by modulating P450 enzymes.

Wang S, Li M, Wang X, Li X, Yin H, Jiang L, Han W, Irving G, Zeng T, Xie K.

Chem Biol Interact. 2017 Mar 1;265:1-7. doi: 10.1016/j.cbi.2017.01.013. Epub 2017 Jan 20.


Taurine inhibits 2,5-hexanedione-induced oxidative stress and mitochondria-dependent apoptosis in PC12 cells.

Li S, Guan H, Qian Z, Sun Y, Gao C, Li G, Yang Y, Piao F, Hu S.

Ind Health. 2017 Apr 7;55(2):108-118. doi: 10.2486/indhealth.2016-0044. Epub 2016 Nov 11.


Solvent exposure and cognitive function in automotive technicians.

Bates MN, Reed BR, Liu S, Eisen EA, Hammond SK.

Neurotoxicology. 2016 Dec;57:22-30. doi: 10.1016/j.neuro.2016.08.009. Epub 2016 Aug 18.


Anti-neuropathic effects of Rosmarinus officinalis L. terpenoid fraction: relevance of nicotinic receptors.

Di Cesare Mannelli L, Micheli L, Maresca M, Cravotto G, Bellumori M, Innocenti M, Mulinacci N, Ghelardini C.

Sci Rep. 2016 Oct 7;6:34832. doi: 10.1038/srep34832.


Bone marrow mesenchymal stem cells attenuate 2,5-hexanedione-induced neuronal apoptosis through a NGF/AKT-dependent pathway.

Wang Q, Sun G, Gao C, Feng L, Zhang Y, Hao J, Zuo E, Zhang C, Li S, Piao F.

Sci Rep. 2016 Oct 5;6:34715. doi: 10.1038/srep34715.


Neuromodulatory effects of Calyptranthes grandifolia extracts against 6-hydroxydopamine-induced neurotoxicity in SH-SY5Y cells.

Kich DM, Bitencourt S, Alves C, Silva J, Pinteus S, Pedrosa R, Laufer S, de Souza CFV, Goettert MI.

Biomed Pharmacother. 2016 Dec;84:382-386. doi: 10.1016/j.biopha.2016.09.063. Epub 2016 Sep 23.


Determination of total urinary 2,5-hexanedione in the Chinese general population.

Xing-Fu P, Ya-Ling Q, Wei Z, Hong-Fang T, Zheng R, Bang-Hua W, Han-Lin H, Yu-Xin Z, Hui-Fang Y.

Environ Res. 2016 Oct;150:645-50. doi: 10.1016/j.envres.2016.05.030. Epub 2016 May 26.


Acquired Color Vision Defects and Hexane Exposure: A Study of San Francisco Bay Area Automotive Mechanics.

Beckman S, Eisen EA, Bates MN, Liu S, Haegerstrom-Portnoy G, Hammond SK.

Am J Epidemiol. 2016 Jun 1;183(11):969-76. doi: 10.1093/aje/kwv328. Epub 2016 May 17.

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