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Items: 1 to 20 of 163

1.

Correction to: Endogenous oligodendroglial alpha-synuclein and TPPP/p25α orchestrate alpha-synuclein pathology in experimental multiple system atrophy models.

Mavroeidi P, Arvanitaki F, Karakitsou AK, Vetsi M, Kloukina I, Zweckstetter M, Giller K, Becker S, Sorrentino ZA, Giasson BI, Jensen PH, Stefanis L, Xilouri M.

Acta Neuropathol. 2019 Sep 3. doi: 10.1007/s00401-019-02068-y. [Epub ahead of print]

PMID:
31485733
2.

Unique α-synuclein pathology within the amygdala in Lewy body dementia: implications for disease initiation and progression.

Sorrentino ZA, Goodwin MS, Riffe CJ, Dhillon JS, Xia Y, Gorion KM, Vijayaraghavan N, McFarland KN, Golbe LI, Yachnis AT, Giasson BI.

Acta Neuropathol Commun. 2019 Sep 2;7(1):142. doi: 10.1186/s40478-019-0787-2.

3.

An anti-CRF antibody suppresses the HPA axis and reverses stress-induced phenotypes.

Futch HS, McFarland KN, Moore BD, Kuhn MZ, Giasson BI, Ladd TB, Scott KA, Shapiro MR, Nosacka RL, Goodwin MS, Ran Y, Cruz PE, Ryu DH, Croft CL, Levites Y, Janus C, Chakrabarty P, Judge AR, Brusko TM, de Kloet AD, Krause EG, Golde TE.

J Exp Med. 2019 Aug 29. pii: jem.20190430. doi: 10.1084/jem.20190430. [Epub ahead of print]

PMID:
31467037
4.

Exploring the Peripheral Initiation of Parkinson's Disease in Animal Models.

Sorrentino ZA, Giasson BI.

Neuron. 2019 Aug 21;103(4):547-549. doi: 10.1016/j.neuron.2019.07.031.

PMID:
31437447
5.

Combining P301L and S320F tau variants produces a novel accelerated model of tauopathy.

Koller EJ, De La Cruz EG, Machula T, Ibanez KR, Lin WL, Williams T, Riffe CJ, Ryu D, Strang KH, Liu X, Janus C, Golde TE, Dickson D, Giasson BI, Chakrabarty P.

Hum Mol Genet. 2019 Jul 1. pii: ddz151. doi: 10.1093/hmg/ddz151. [Epub ahead of print]

PMID:
31261380
6.

Comparative analyses of the in vivo induction and transmission of α-synuclein pathology in transgenic mice by MSA brain lysate and recombinant α-synuclein fibrils.

Dhillon JS, Trejo-Lopez JA, Riffe C, Levites Y, Sacino AN, Borchelt DR, Yachnis AY, Giasson BI.

Acta Neuropathol Commun. 2019 May 20;7(1):80. doi: 10.1186/s40478-019-0733-3.

7.

Endogenous oligodendroglial alpha-synuclein and TPPP/p25α orchestrate alpha-synuclein pathology in experimental multiple system atrophy models.

Mavroeidi P, Arvanitaki F, Karakitsou AK, Vetsi M, Kloukina I, Zweckstetter M, Giller K, Becker S, Sorrentino ZA, Giasson BI, Jensen PH, Stefanis L, Xilouri M.

Acta Neuropathol. 2019 Sep;138(3):415-441. doi: 10.1007/s00401-019-02014-y. Epub 2019 Apr 22. Erratum in: Acta Neuropathol. 2019 Sep 3;:.

PMID:
31011860
8.

α-Synuclein and astrocytes: tracing the pathways from homeostasis to neurodegeneration in Lewy body disease.

Sorrentino ZA, Giasson BI, Chakrabarty P.

Acta Neuropathol. 2019 Jul;138(1):1-21. doi: 10.1007/s00401-019-01977-2. Epub 2019 Feb 23. Review.

PMID:
30798354
9.

rAAV-based brain slice culture models of Alzheimer's and Parkinson's disease inclusion pathologies.

Croft CL, Cruz PE, Ryu DH, Ceballos-Diaz C, Strang KH, Woody BM, Lin WL, Deture M, Rodríguez-Lebrón E, Dickson DW, Chakrabarty P, Levites Y, Giasson BI, Golde TE.

J Exp Med. 2019 Mar 4;216(3):539-555. doi: 10.1084/jem.20182184. Epub 2019 Feb 15.

10.

MAPT mutations, tauopathy, and mechanisms of neurodegeneration.

Strang KH, Golde TE, Giasson BI.

Lab Invest. 2019 Jul;99(7):912-928. doi: 10.1038/s41374-019-0197-x. Epub 2019 Feb 11. Review.

PMID:
30742061
11.

Dissecting α-synuclein inclusion pathology diversity in multiple system atrophy: implications for the prion-like transmission hypothesis.

Dhillon JS, Trejo-Lopez JA, Riffe C, McFarland NR, Hiser WM, Giasson BI, Yachnis AT.

Lab Invest. 2019 Jul;99(7):982-992. doi: 10.1038/s41374-019-0198-9. Epub 2019 Feb 8. Review.

PMID:
30737468
12.

Phosphorylation of serine 305 in tau inhibits aggregation.

Strang KH, Sorrentino ZA, Riffe CJ, Gorion KM, Vijayaraghavan N, Golde TE, Giasson BI.

Neurosci Lett. 2019 Jan 23;692:187-192. doi: 10.1016/j.neulet.2018.11.011. Epub 2018 Nov 10.

PMID:
30423399
13.

Physiological C-terminal truncation of α-synuclein potentiates the prion-like formation of pathological inclusions.

Sorrentino ZA, Vijayaraghavan N, Gorion KM, Riffe CJ, Strang KH, Caldwell J, Giasson BI.

J Biol Chem. 2018 Dec 7;293(49):18914-18932. doi: 10.1074/jbc.RA118.005603. Epub 2018 Oct 16.

PMID:
30327435
14.

Designing antibodies against LRRK2-targeted tau epitopes.

Hamm M, Ladd TB, Levites Y, Golde TE, Giasson BI, Lewis J.

PLoS One. 2018 Sep 27;13(9):e0204367. doi: 10.1371/journal.pone.0204367. eCollection 2018.

15.

Motor neuron loss and neuroinflammation in a model of α-synuclein-induced neurodegeneration.

Sorrentino ZA, Xia Y, Funk C, Riffe CJ, Rutherford NJ, Ceballos Diaz C, Sacino AN, Price ND, Golde TE, Giasson BI, Chakrabarty P.

Neurobiol Dis. 2018 Dec;120:98-106. doi: 10.1016/j.nbd.2018.09.005. Epub 2018 Sep 6.

PMID:
30195075
16.

TLR5 decoy receptor as a novel anti-amyloid therapeutic for Alzheimer's disease.

Chakrabarty P, Li A, Ladd TB, Strickland MR, Koller EJ, Burgess JD, Funk CC, Cruz PE, Allen M, Yaroshenko M, Wang X, Younkin C, Reddy J, Lohrer B, Mehrke L, Moore BD, Liu X, Ceballos-Diaz C, Rosario AM, Medway C, Janus C, Li HD, Dickson DW, Giasson BI, Price ND, Younkin SG, Ertekin-Taner N, Golde TE.

J Exp Med. 2018 Sep 3;215(9):2247-2264. doi: 10.1084/jem.20180484.

17.

Changes in proteome solubility indicate widespread proteostatic disruption in mouse models of neurodegenerative disease.

Pace MC, Xu G, Fromholt S, Howard J, Crosby K, Giasson BI, Lewis J, Borchelt DR.

Acta Neuropathol. 2018 Dec;136(6):919-938. doi: 10.1007/s00401-018-1895-y. Epub 2018 Aug 23.

18.

Localized Induction of Wild-Type and Mutant Alpha-Synuclein Aggregation Reveals Propagation along Neuroanatomical Tracts.

Ayers JI, Riffe CJ, Sorrentino ZA, Diamond J, Fagerli E, Brooks M, Galaleldeen A, Hart PJ, Giasson BI.

J Virol. 2018 Aug 29;92(18). pii: e00586-18. doi: 10.1128/JVI.00586-18. Print 2018 Sep 15.

19.

Partial loss of ATP13A2 causes selective gliosis independent of robust lipofuscinosis.

Rayaprolu S, Seven YB, Howard J, Duffy C, Altshuler M, Moloney C, Giasson BI, Lewis J.

Mol Cell Neurosci. 2018 Oct;92:17-26. doi: 10.1016/j.mcn.2018.05.009. Epub 2018 Jun 1.

PMID:
29859891
20.

Differential induction of mutant SOD1 misfolding and aggregation by tau and α-synuclein pathology.

Pace MC, Xu G, Fromholt S, Howard J, Giasson BI, Lewis J, Borchelt DR.

Mol Neurodegener. 2018 May 18;13(1):23. doi: 10.1186/s13024-018-0253-9.

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