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Items: 16


A Systematic Analysis of Factors Localized to Damaged Chromatin Reveals PARP-Dependent Recruitment of Transcription Factors.

Izhar L, Adamson B, Ciccia A, Lewis J, Pontano-Vaites L, Leng Y, Liang AC, Westbrook TF, Harper JW, Elledge SJ.

Cell Rep. 2015 Jun 9;11(9):1486-500. doi: 10.1016/j.celrep.2015.04.053. Epub 2015 May 21.


Treacher Collins syndrome TCOF1 protein cooperates with NBS1 in the DNA damage response.

Ciccia A, Huang JW, Izhar L, Sowa ME, Harper JW, Elledge SJ.

Proc Natl Acad Sci U S A. 2014 Dec 30;111(52):18631-6. doi: 10.1073/pnas.1422488112. Epub 2014 Dec 15.


Protein interaction discovery using parallel analysis of translated ORFs (PLATO).

Zhu J, Larman HB, Gao G, Somwar R, Zhang Z, Laserson U, Ciccia A, Pavlova N, Church G, Zhang W, Kesari S, Elledge SJ.

Nat Biotechnol. 2013 Apr;31(4):331-334. doi: 10.1038/nbt.2539. Epub 2013 Mar 17.


Polyubiquitinated PCNA recruits the ZRANB3 translocase to maintain genomic integrity after replication stress.

Ciccia A, Nimonkar AV, Hu Y, Hajdu I, Achar YJ, Izhar L, Petit SA, Adamson B, Yoon JC, Kowalczykowski SC, Livingston DM, Haracska L, Elledge SJ.

Mol Cell. 2012 Aug 10;47(3):396-409. doi: 10.1016/j.molcel.2012.05.024. Epub 2012 Jun 14.


Wolf-Hirschhorn syndrome candidate 1 is involved in the cellular response to DNA damage.

Hajdu I, Ciccia A, Lewis SM, Elledge SJ.

Proc Natl Acad Sci U S A. 2011 Aug 9;108(32):13130-4. doi: 10.1073/pnas.1110081108. Epub 2011 Jul 25.


Proliferating cell nuclear antigen (PCNA)-associated KIAA0101/PAF15 protein is a cell cycle-regulated anaphase-promoting complex/cyclosome substrate.

Emanuele MJ, Ciccia A, Elia AE, Elledge SJ.

Proc Natl Acad Sci U S A. 2011 Jun 14;108(24):9845-50. doi: 10.1073/pnas.1106136108. Epub 2011 May 31.


Autoantigen discovery with a synthetic human peptidome.

Larman HB, Zhao Z, Laserson U, Li MZ, Ciccia A, Gakidis MA, Church GM, Kesari S, Leproust EM, Solimini NL, Elledge SJ.

Nat Biotechnol. 2011 May 22;29(6):535-41. doi: 10.1038/nbt.1856.


The pINDUCER lentiviral toolkit for inducible RNA interference in vitro and in vivo.

Meerbrey KL, Hu G, Kessler JD, Roarty K, Li MZ, Fang JE, Herschkowitz JI, Burrows AE, Ciccia A, Sun T, Schmitt EM, Bernardi RJ, Fu X, Bland CS, Cooper TA, Schiff R, Rosen JM, Westbrook TF, Elledge SJ.

Proc Natl Acad Sci U S A. 2011 Mar 1;108(9):3665-70. doi: 10.1073/pnas.1019736108. Epub 2011 Feb 9.


A genome-wide camptothecin sensitivity screen identifies a mammalian MMS22L-NFKBIL2 complex required for genomic stability.

O'Connell BC, Adamson B, Lydeard JR, Sowa ME, Ciccia A, Bredemeyer AL, Schlabach M, Gygi SP, Elledge SJ, Harper JW.

Mol Cell. 2010 Nov 24;40(4):645-57. doi: 10.1016/j.molcel.2010.10.022. Epub 2010 Nov 4.


The DNA damage response: making it safe to play with knives.

Ciccia A, Elledge SJ.

Mol Cell. 2010 Oct 22;40(2):179-204. doi: 10.1016/j.molcel.2010.09.019. Review.


The SIOD disorder protein SMARCAL1 is an RPA-interacting protein involved in replication fork restart.

Ciccia A, Bredemeyer AL, Sowa ME, Terret ME, Jallepalli PV, Harper JW, Elledge SJ.

Genes Dev. 2009 Oct 15;23(20):2415-25. doi: 10.1101/gad.1832309. Epub 2009 Sep 30.


FANCM and FAAP24 function in ATR-mediated checkpoint signaling independently of the Fanconi anemia core complex.

Collis SJ, Ciccia A, Deans AJ, Horejsí Z, Martin JS, Maslen SL, Skehel JM, Elledge SJ, West SC, Boulton SJ.

Mol Cell. 2008 Nov 7;32(3):313-24. doi: 10.1016/j.molcel.2008.10.014.


Structural and functional relationships of the XPF/MUS81 family of proteins.

Ciccia A, McDonald N, West SC.

Annu Rev Biochem. 2008;77:259-87. doi: 10.1146/annurev.biochem.77.070306.102408. Review.


Identification of FAAP24, a Fanconi anemia core complex protein that interacts with FANCM.

Ciccia A, Ling C, Coulthard R, Yan Z, Xue Y, Meetei AR, Laghmani el H, Joenje H, McDonald N, de Winter JP, Wang W, West SC.

Mol Cell. 2007 Feb 9;25(3):331-43.


Eme1 is involved in DNA damage processing and maintenance of genomic stability in mammalian cells.

Abraham J, Lemmers B, Hande MP, Moynahan ME, Chahwan C, Ciccia A, Essers J, Hanada K, Chahwan R, Khaw AK, McPherson P, Shehabeldin A, Laister R, Arrowsmith C, Kanaar R, West SC, Jasin M, Hakem R.

EMBO J. 2003 Nov 17;22(22):6137-47.


Identification and characterization of the human mus81-eme1 endonuclease.

Ciccia A, Constantinou A, West SC.

J Biol Chem. 2003 Jul 4;278(27):25172-8. Epub 2003 Apr 29.

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