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Items: 1 to 20 of 116


Pyramidal cell-selective GluN1 knockout causes impairments in salience attribution and related EEG activity.

Forrest AD, Bang J, Featherstone RE, Bloom JH, Luminais MS, Zhang RV, Gajewski CR, McMullen MF, Liang Y, Siegel SJ.

Exp Brain Res. 2018 Mar;236(3):837-846. doi: 10.1007/s00221-017-5152-8. Epub 2018 Jan 19.


Protocadherin 10 alters γ oscillations, amino acid levels, and their coupling; baclofen partially restores these oscillatory deficits.

Port RG, Gajewski C, Krizman E, Dow HC, Hirano S, Brodkin ES, Carlson GC, Robinson MB, Roberts TPL, Siegel SJ.

Neurobiol Dis. 2017 Dec;108:324-338. doi: 10.1016/j.nbd.2017.08.013. Epub 2017 Aug 24.


GABA-B Agonist Baclofen Normalizes Auditory-Evoked Neural Oscillations and Behavioral Deficits in the Fmr1 Knockout Mouse Model of Fragile X Syndrome.

Sinclair D, Featherstone R, Naschek M, Nam J, Du A, Wright S, Pance K, Melnychenko O, Weger R, Akuzawa S, Matsumoto M, Siegel SJ.

eNeuro. 2017 Mar 1;4(1). pii: ENEURO.0380-16.2017. doi: 10.1523/ENEURO.0380-16.2017. eCollection 2017 Jan-Feb.


Amygdala activity associated with social choice in mice.

Mihara T, Mensah-Brown K, Sobota R, Lin R, Featherstone R, Siegel SJ.

Behav Brain Res. 2017 Aug 14;332:84-89. doi: 10.1016/j.bbr.2017.04.040. Epub 2017 Apr 21.


Multiple Drug Treatments That Increase cAMP Signaling Restore Long-Term Memory and Aberrant Signaling in Fragile X Syndrome Models.

Choi CH, Schoenfeld BP, Bell AJ, Hinchey J, Rosenfelt C, Gertner MJ, Campbell SR, Emerson D, Hinchey P, Kollaros M, Ferrick NJ, Chambers DB, Langer S, Sust S, Malik A, Terlizzi AM, Liebelt DA, Ferreiro D, Sharma A, Koenigsberg E, Choi RJ, Louneva N, Arnold SE, Featherstone RE, Siegel SJ, Zukin RS, McDonald TV, Bolduc FV, Jongens TA, McBride SM.

Front Behav Neurosci. 2016 Jun 30;10:136. doi: 10.3389/fnbeh.2016.00136. eCollection 2016.


Sensory processing in autism spectrum disorders and Fragile X syndrome-From the clinic to animal models.

Sinclair D, Oranje B, Razak KA, Siegel SJ, Schmid S.

Neurosci Biobehav Rev. 2017 May;76(Pt B):235-253. doi: 10.1016/j.neubiorev.2016.05.029. Epub 2016 May 24. Review.


Lysosomal iron modulates NMDA receptor-mediated excitation via small GTPase, Dexras1.

White RS, Bhattacharya AK, Chen Y, Byrd M, McMullen MF, Siegel SJ, Carlson GC, Kim SF.

Mol Brain. 2016 Apr 14;9:38. doi: 10.1186/s13041-016-0220-8.


Dexras1 a unique ras-GTPase interacts with NMDA receptor activity and provides a novel dissociation between anxiety, working memory and sensory gating.

Carlson GC, Lin RE, Chen Y, Brookshire BR, White RS, Lucki I, Siegel SJ, Kim SF.

Neuroscience. 2016 May 13;322:408-15. doi: 10.1016/j.neuroscience.2016.02.063. Epub 2016 Mar 3.


Mouse Model of Chromosome 15q13.3 Microdeletion Syndrome Demonstrates Features Related to Autism Spectrum Disorder.

Kogan JH, Gross AK, Featherstone RE, Shin R, Chen Q, Heusner CL, Adachi M, Lin A, Walton NM, Miyoshi S, Miyake S, Tajinda K, Ito H, Siegel SJ, Matsumoto M.

J Neurosci. 2015 Dec 9;35(49):16282-94. doi: 10.1523/JNEUROSCI.3967-14.2015.


Cellular and circuit models of increased resting-state network gamma activity in schizophrenia.

White RS, Siegel SJ.

Neuroscience. 2016 May 3;321:66-76. doi: 10.1016/j.neuroscience.2015.11.011. Epub 2015 Nov 11. Review.


The Role of Nicotine in Schizophrenia.

Featherstone RE, Siegel SJ.

Int Rev Neurobiol. 2015;124:23-78. doi: 10.1016/bs.irn.2015.07.002. Epub 2015 Aug 21. Review.


Ceftriaxone reverses ketamine-induced lasting EEG and astrocyte alterations in juvenile mice.

Dodman K, Featherstone RE, Bang J, Liang Y, Siegel SJ.

Drug Alcohol Depend. 2015 Nov 1;156:14-20. doi: 10.1016/j.drugalcdep.2015.07.1198. Epub 2015 Sep 21.


Delayed emergence of behavioral and electrophysiological effects following juvenile ketamine exposure in mice.

Nagy LR, Featherstone RE, Hahn CG, Siegel SJ.

Transl Psychiatry. 2015 Sep 15;5:e635. doi: 10.1038/tp.2015.111.


Oxytocin reduces amygdala activity, increases social interactions, and reduces anxiety-like behavior irrespective of NMDAR antagonism.

Sobota R, Mihara T, Forrest A, Featherstone RE, Siegel SJ.

Behav Neurosci. 2015 Aug;129(4):389-98. doi: 10.1037/bne0000074.


Clearance of Pneumococcal Colonization in Infants Is Delayed through Altered Macrophage Trafficking.

Siegel SJ, Tamashiro E, Weiser JN.

PLoS Pathog. 2015 Jun 24;11(6):e1005004. doi: 10.1371/journal.ppat.1005004. eCollection 2015 Jun.


EEG biomarkers of target engagement, therapeutic effect, and disease process.

Featherstone RE, McMullen MF, Ward KR, Bang J, Xiao J, Siegel SJ.

Ann N Y Acad Sci. 2015 May;1344:12-26. doi: 10.1111/nyas.12745. Epub 2015 Mar 30.


Prospective MEG biomarkers in ASD: pre-clinical evidence and clinical promise of electrophysiological signatures.

Port RG, Anwar AR, Ku M, Carlson GC, Siegel SJ, Roberts TP.

Yale J Biol Med. 2015 Mar 4;88(1):25-36. eCollection 2015 Mar. Review.


PDE-4 inhibition rescues aberrant synaptic plasticity in Drosophila and mouse models of fragile X syndrome.

Choi CH, Schoenfeld BP, Weisz ED, Bell AJ, Chambers DB, Hinchey J, Choi RJ, Hinchey P, Kollaros M, Gertner MJ, Ferrick NJ, Terlizzi AM, Yohn N, Koenigsberg E, Liebelt DA, Zukin RS, Woo NH, Tranfaglia MR, Louneva N, Arnold SE, Siegel SJ, Bolduc FV, McDonald TV, Jongens TA, McBride SM.

J Neurosci. 2015 Jan 7;35(1):396-408. doi: 10.1523/JNEUROSCI.1356-12.2015.


Convergence of circuit dysfunction in ASD: a common bridge between diverse genetic and environmental risk factors and common clinical electrophysiology.

Port RG, Gandal MJ, Roberts TP, Siegel SJ, Carlson GC.

Front Cell Neurosci. 2014 Dec 8;8:414. doi: 10.3389/fncel.2014.00414. eCollection 2014. Review.


Mice with subtle reduction of NMDA NR1 receptor subunit expression have a selective decrease in mismatch negativity: Implications for schizophrenia prodromal population.

Featherstone RE, Shin R, Kogan JH, Liang Y, Matsumoto M, Siegel SJ.

Neurobiol Dis. 2015 Jan;73:289-95. doi: 10.1016/j.nbd.2014.10.010. Epub 2014 Oct 22.


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