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Items: 1 to 20 of 35

1.

Peptide-based sequestration of the adaptor protein Nck1 in pancreatic β cells enhances insulin biogenesis and protects against diabetogenic stresses.

Kefalas G, Jouvet N, Baldwin C, Estall JL, Larose L.

J Biol Chem. 2018 Aug 10;293(32):12516-12524. doi: 10.1074/jbc.RA118.002728. Epub 2018 Jun 25.

PMID:
29941454
2.

Linking Metabolic Disease With the PGC-1α Gly482Ser Polymorphism.

Vandenbeek R, Khan NP, Estall JL.

Endocrinology. 2018 Feb 1;159(2):853-865. doi: 10.1210/en.2017-00872. Review.

PMID:
29186342
3.

The pancreas: Bandmaster of glucose homeostasis.

Jouvet N, Estall JL.

Exp Cell Res. 2017 Nov 1;360(1):19-23. doi: 10.1016/j.yexcr.2017.03.050. Epub 2017 Mar 27. Review.

PMID:
28351751
4.

Estrogen Signals Through Peroxisome Proliferator-Activated Receptor-γ Coactivator 1α to Reduce Oxidative Damage Associated With Diet-Induced Fatty Liver Disease.

Besse-Patin A, Léveillé M, Oropeza D, Nguyen BN, Prat A, Estall JL.

Gastroenterology. 2017 Jan;152(1):243-256. doi: 10.1053/j.gastro.2016.09.017. Epub 2016 Sep 20.

PMID:
27658772
5.

Searching for the β-Cell Fountain of Youth.

Jouvet N, Estall JL.

Endocrinology. 2016 Sep;157(9):3388-90. doi: 10.1210/en.2016-1561.

PMID:
27580804
6.

PGC-1 coactivators in β-cells regulate lipid metabolism and are essential for insulin secretion coupled to fatty acids.

Oropeza D, Jouvet N, Bouyakdan K, Perron G, Ringuette LJ, Philipson LH, Kiss RS, Poitout V, Alquier T, Estall JL.

Mol Metab. 2015 Aug 14;4(11):811-22. doi: 10.1016/j.molmet.2015.08.001. eCollection 2015 Nov.

7.

Phenotypic Characterization of MIP-CreERT1Lphi Mice With Transgene-Driven Islet Expression of Human Growth Hormone.

Oropeza D, Jouvet N, Budry L, Campbell JE, Bouyakdan K, Lacombe J, Perron G, Bergeron V, Neuman JC, Brar HK, Fenske RJ, Meunier C, Sczelecki S, Kimple ME, Drucker DJ, Screaton RA, Poitout V, Ferron M, Alquier T, Estall JL.

Diabetes. 2015 Nov;64(11):3798-807. doi: 10.2337/db15-0272. Epub 2015 Jul 7.

8.

To Be(ta Cell) or Not to Be(ta cell): New Mouse Models for Studying Gene Function in the Pancreatic β-Cell.

Estall JL, Screaton RA.

Endocrinology. 2015 Jul;156(7):2365-7. doi: 10.1210/en.2015-1418.

PMID:
26091426
9.

An Intimate Relationship between ROS and Insulin Signalling: Implications for Antioxidant Treatment of Fatty Liver Disease.

Besse-Patin A, Estall JL.

Int J Cell Biol. 2014;2014:519153. doi: 10.1155/2014/519153. Epub 2014 Feb 12. Review.

10.

β-Aminoisobutyric acid induces browning of white fat and hepatic β-oxidation and is inversely correlated with cardiometabolic risk factors.

Roberts LD, Boström P, O'Sullivan JF, Schinzel RT, Lewis GD, Dejam A, Lee YK, Palma MJ, Calhoun S, Georgiadi A, Chen MH, Ramachandran VS, Larson MG, Bouchard C, Rankinen T, Souza AL, Clish CB, Wang TJ, Estall JL, Soukas AA, Cowan CA, Spiegelman BM, Gerszten RE.

Cell Metab. 2014 Jan 7;19(1):96-108. doi: 10.1016/j.cmet.2013.12.003.

11.

Loss of Pgc-1α expression in aging mouse muscle potentiates glucose intolerance and systemic inflammation.

Sczelecki S, Besse-Patin A, Abboud A, Kleiner S, Laznik-Bogoslavski D, Wrann CD, Ruas JL, Haibe-Kains B, Estall JL.

Am J Physiol Endocrinol Metab. 2014 Jan 15;306(2):E157-67. doi: 10.1152/ajpendo.00578.2013. Epub 2013 Nov 26.

12.

The protein level of PGC-1α, a key metabolic regulator, is controlled by NADH-NQO1.

Adamovich Y, Shlomai A, Tsvetkov P, Umansky KB, Reuven N, Estall JL, Spiegelman BM, Shaul Y.

Mol Cell Biol. 2013 Jul;33(13):2603-13. doi: 10.1128/MCB.01672-12. Epub 2013 May 6.

13.

A PGC-1α isoform induced by resistance training regulates skeletal muscle hypertrophy.

Ruas JL, White JP, Rao RR, Kleiner S, Brannan KT, Harrison BC, Greene NP, Wu J, Estall JL, Irving BA, Lanza IR, Rasbach KA, Okutsu M, Nair KS, Yan Z, Leinwand LA, Spiegelman BM.

Cell. 2012 Dec 7;151(6):1319-31. doi: 10.1016/j.cell.2012.10.050.

14.

Development of insulin resistance in mice lacking PGC-1α in adipose tissues.

Kleiner S, Mepani RJ, Laznik D, Ye L, Jurczak MJ, Jornayvaz FR, Estall JL, Chatterjee Bhowmick D, Shulman GI, Spiegelman BM.

Proc Natl Acad Sci U S A. 2012 Jun 12;109(24):9635-40. doi: 10.1073/pnas.1207287109. Epub 2012 May 29.

15.

The Foxo family: partners in crime or silent heroes.

Estall JL.

Endocrinology. 2012 Feb;153(2):549-51. doi: 10.1210/en.2011-2080. No abstract available.

PMID:
22267684
16.

Integrated regulation of hepatic metabolism by fibroblast growth factor 21 (FGF21) in vivo.

Fisher FM, Estall JL, Adams AC, Antonellis PJ, Bina HA, Flier JS, Kharitonenkov A, Spiegelman BM, Maratos-Flier E.

Endocrinology. 2011 Aug;152(8):2996-3004. doi: 10.1210/en.2011-0281. Epub 2011 Jun 28.

17.

Separation of the gluconeogenic and mitochondrial functions of PGC-1{alpha} through S6 kinase.

Lustig Y, Ruas JL, Estall JL, Lo JC, Devarakonda S, Laznik D, Choi JH, Ono H, Olsen JV, Spiegelman BM.

Genes Dev. 2011 Jun 15;25(12):1232-44. doi: 10.1101/gad.2054711. Epub 2011 Jun 6.

18.

Transcriptional control of adipose lipid handling by IRF4.

Eguchi J, Wang X, Yu S, Kershaw EE, Chiu PC, Dushay J, Estall JL, Klein U, Maratos-Flier E, Rosen ED.

Cell Metab. 2011 Mar 2;13(3):249-59. doi: 10.1016/j.cmet.2011.02.005.

19.

The unfolded protein response mediates adaptation to exercise in skeletal muscle through a PGC-1α/ATF6α complex.

Wu J, Ruas JL, Estall JL, Rasbach KA, Choi JH, Ye L, Boström P, Tyra HM, Crawford RW, Campbell KP, Rutkowski DT, Kaufman RJ, Spiegelman BM.

Cell Metab. 2011 Feb 2;13(2):160-9. doi: 10.1016/j.cmet.2011.01.003.

20.

Prdm16 determines the thermogenic program of subcutaneous white adipose tissue in mice.

Seale P, Conroe HM, Estall J, Kajimura S, Frontini A, Ishibashi J, Cohen P, Cinti S, Spiegelman BM.

J Clin Invest. 2011 Jan;121(1):96-105. doi: 10.1172/JCI44271. Epub 2010 Dec 1.

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