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Items: 1 to 20 of 96


EdgeProps: A Computational Platform for Correlative Analysis of Cell Dynamics and Near-Edge Protein Activity.

Zhurikhina A, Qi T, Hahn KM, Elston TC, Tsygankov D.

Methods Mol Biol. 2018;1821:47-56. doi: 10.1007/978-1-4939-8612-5_4.


Principles that govern competition or co-existence in Rho-GTPase driven polarization.

Chiou JG, Ramirez SA, Elston TC, Witelski TP, Schaeffer DG, Lew DJ.

PLoS Comput Biol. 2018 Apr 12;14(4):e1006095. doi: 10.1371/journal.pcbi.1006095. eCollection 2018 Apr.


Particle-based simulations of polarity establishment reveal stochastic promotion of Turing pattern formation.

Pablo M, Ramirez SA, Elston TC.

PLoS Comput Biol. 2018 Mar 12;14(3):e1006016. doi: 10.1371/journal.pcbi.1006016. eCollection 2018 Mar.


An RNAi screen of Rho signalling networks identifies RhoH as a regulator of Rac1 in prostate cancer cell migration.

Tajadura-Ortega V, Garg R, Allen R, Owczarek C, Bright MD, Kean S, Mohd-Noor A, Grigoriadis A, Elston TC, Hahn KM, Ridley AJ.

BMC Biol. 2018 Mar 6;16(1):29. doi: 10.1186/s12915-018-0489-4.


Dose-Duration Reciprocity for G protein activation: Modulation of kinase to substrate ratio alters cell signaling.

Liao KL, Melvin CE, Sozzani R, Jones RD, Elston TC, Jones AM.

PLoS One. 2017 Dec 29;12(12):e0190000. doi: 10.1371/journal.pone.0190000. eCollection 2017.


Mathematical model reveals role of nucleotide signaling in airway surface liquid homeostasis and its dysregulation in cystic fibrosis.

Sandefur CI, Boucher RC, Elston TC.

Proc Natl Acad Sci U S A. 2017 Aug 29;114(35):E7272-E7281. doi: 10.1073/pnas.1617383114. Epub 2017 Aug 14.


A Reaction-Diffusion Model Explains Amplification of the PLC/PKC Pathway in Fibroblast Chemotaxis.

Mohan K, Nosbisch JL, Elston TC, Bear JE, Haugh JM.

Biophys J. 2017 Jul 11;113(1):185-194. doi: 10.1016/j.bpj.2017.05.035.


Testing the limits of gradient sensing.

Lakhani V, Elston TC.

PLoS Comput Biol. 2017 Feb 16;13(2):e1005386. doi: 10.1371/journal.pcbi.1005386. eCollection 2017 Feb.


A shadow detector for photosynthesis efficiency.

Liao KL, Jones RD, McCarter P, Tunc-Ozdemir M, Draper JA, Elston TC, Kramer D, Jones AM.

J Theor Biol. 2017 Feb 7;414:231-244. doi: 10.1016/j.jtbi.2016.11.027. Epub 2016 Dec 3.


Modeling the Excess Cell Surface Stored in a Complex Morphology of Bleb-Like Protrusions.

Kapustina M, Tsygankov D, Zhao J, Wessler T, Yang X, Chen A, Roach N, Elston TC, Wang Q, Jacobson K, Forest MG.

PLoS Comput Biol. 2016 Mar 25;12(3):e1004841. doi: 10.1371/journal.pcbi.1004841. eCollection 2016 Mar.


Role of Polarized G Protein Signaling in Tracking Pheromone Gradients.

McClure AW, Minakova M, Dyer JM, Zyla TR, Elston TC, Lew DJ.

Dev Cell. 2015 Nov 23;35(4):471-82. doi: 10.1016/j.devcel.2015.10.024.


Spatio-Temporal Regulation of Rac1 Mobility by Actin Islands.

Lakhani VV, Hinde E, Gratton E, Elston TC.

PLoS One. 2015 Nov 25;10(11):e0143753. doi: 10.1371/journal.pone.0143753. eCollection 2015.


Role of competition between polarity sites in establishing a unique front.

Wu CF, Chiou JG, Minakova M, Woods B, Tsygankov D, Zyla TR, Savage NS, Elston TC, Lew DJ.

Elife. 2015 Nov 2;4. pii: e11611. doi: 10.7554/eLife.11611.


Expression of an S phase-stabilized version of the CDK inhibitor Dacapo can alter endoreplication.

Swanson CI, Meserve JH, McCarter PC, Thieme A, Mathew T, Elston TC, Duronio RJ.

Development. 2015 Dec 15;142(24):4288-98. doi: 10.1242/dev.115006. Epub 2015 Oct 22.


Modulation of receptor dynamics by the regulator of G protein signaling Sst2.

Venkatapurapu SP, Kelley JB, Dixit G, Pena M, Errede B, Dohlman HG, Elston TC.

Mol Biol Cell. 2015 Nov 5;26(22):4124-34. doi: 10.1091/mbc.E14-12-1635. Epub 2015 Aug 26.


Divergent roles of CAAX motif-signaled posttranslational modifications in the regulation and subcellular localization of Ral GTPases.

Gentry LR, Nishimura A, Cox AD, Martin TD, Tsygankov D, Nishida M, Elston TC, Der CJ.

J Biol Chem. 2015 Sep 11;290(37):22851-61. doi: 10.1074/jbc.M115.656710. Epub 2015 Jul 27.


Pheromone-induced morphogenesis and gradient tracking are dependent on the MAPK Fus3 binding to Gα.

Errede B, Vered L, Ford E, Pena MI, Elston TC.

Mol Biol Cell. 2015 Sep 15;26(18):3343-58. doi: 10.1091/mbc.E15-03-0176. Epub 2015 Jul 15.


Signal inhibition by a dynamically regulated pool of monophosphorylated MAPK.

Nagiec MJ, McCarter PC, Kelley JB, Dixit G, Elston TC, Dohlman HG.

Mol Biol Cell. 2015 Sep 15;26(18):3359-71. doi: 10.1091/mbc.E15-01-0037. Epub 2015 Jul 15.


RGS proteins and septins cooperate to promote chemotropism by regulating polar cap mobility.

Kelley JB, Dixit G, Sheetz JB, Venkatapurapu SP, Elston TC, Dohlman HG.

Curr Biol. 2015 Feb 2;25(3):275-285. doi: 10.1016/j.cub.2014.11.047. Epub 2015 Jan 15.


MAPK feedback encodes a switch and timer for tunable stress adaptation in yeast.

English JG, Shellhammer JP, Malahe M, McCarter PC, Elston TC, Dohlman HG.

Sci Signal. 2015 Jan 13;8(359):ra5. doi: 10.1126/scisignal.2005774.

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