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Items: 16


PhIP-Seq characterization of autoantibodies from patients with multiple sclerosis, type 1 diabetes and rheumatoid arthritis.

Larman HB, Laserson U, Querol L, Verhaeghen K, Solimini NL, Xu GJ, Klarenbeek PL, Church GM, Hafler DA, Plenge RM, Nigrovic PA, De Jager PL, Weets I, Martens GA, O'Connor KC, Elledge SJ.

J Autoimmun. 2013 Jun;43:1-9. doi: 10.1016/j.jaut.2013.01.013. Epub 2013 Mar 13.


STOP gene Phactr4 is a tumor suppressor.

Solimini NL, Liang AC, Xu C, Pavlova NN, Xu Q, Davoli T, Li MZ, Wong KK, Elledge SJ.

Proc Natl Acad Sci U S A. 2013 Jan 29;110(5):E407-14. doi: 10.1073/pnas.1221385110. Epub 2013 Jan 14.


Recurrent hemizygous deletions in cancers may optimize proliferative potential.

Solimini NL, Xu Q, Mermel CH, Liang AC, Schlabach MR, Luo J, Burrows AE, Anselmo AN, Bredemeyer AL, Li MZ, Beroukhim R, Meyerson M, Elledge SJ.

Science. 2012 Jul 6;337(6090):104-9. doi: 10.1126/science.1219580. Epub 2012 May 24.


Akt and ERK control the proliferative response of mammary epithelial cells to the growth factors IGF-1 and EGF through the cell cycle inhibitor p57Kip2.

Worster DT, Schmelzle T, Solimini NL, Lightcap ES, Millard B, Mills GB, Brugge JS, Albeck JG.

Sci Signal. 2012 Mar 6;5(214):ra19. doi: 10.1126/scisignal.2001986.


A SUMOylation-dependent transcriptional subprogram is required for Myc-driven tumorigenesis.

Kessler JD, Kahle KT, Sun T, Meerbrey KL, Schlabach MR, Schmitt EM, Skinner SO, Xu Q, Li MZ, Hartman ZC, Rao M, Yu P, Dominguez-Vidana R, Liang AC, Solimini NL, Bernardi RJ, Yu B, Hsu T, Golding I, Luo J, Osborne CK, Creighton CJ, Hilsenbeck SG, Schiff R, Shaw CA, Elledge SJ, Westbrook TF.

Science. 2012 Jan 20;335(6066):348-53. doi: 10.1126/science.1212728. Epub 2011 Dec 8.


Autoantigen discovery with a synthetic human peptidome.

Larman HB, Zhao Z, Laserson U, Li MZ, Ciccia A, Gakidis MA, Church GM, Kesari S, Leproust EM, Solimini NL, Elledge SJ.

Nat Biotechnol. 2011 May 22;29(6):535-41. doi: 10.1038/nbt.1856.


Principles of cancer therapy: oncogene and non-oncogene addiction.

Luo J, Solimini NL, Elledge SJ.

Cell. 2009 Mar 6;136(5):823-37. doi: 10.1016/j.cell.2009.02.024. Erratum in: Cell. 2009 Aug 21;138(4):807.


Cancer proliferation gene discovery through functional genomics.

Schlabach MR, Luo J, Solimini NL, Hu G, Xu Q, Li MZ, Zhao Z, Smogorzewska A, Sowa ME, Ang XL, Westbrook TF, Liang AC, Chang K, Hackett JA, Harper JW, Hannon GJ, Elledge SJ.

Science. 2008 Feb 1;319(5863):620-4. doi: 10.1126/science.1149200. Erratum in: Science.2008 Apr 18;320(5874):316.


Non-oncogene addiction and the stress phenotype of cancer cells.

Solimini NL, Luo J, Elledge SJ.

Cell. 2007 Sep 21;130(6):986-8.


ATM and ATR substrate analysis reveals extensive protein networks responsive to DNA damage.

Matsuoka S, Ballif BA, Smogorzewska A, McDonald ER 3rd, Hurov KE, Luo J, Bakalarski CE, Zhao Z, Solimini N, Lerenthal Y, Shiloh Y, Gygi SP, Elledge SJ.

Science. 2007 May 25;316(5828):1160-6.


Functional role and oncogene-regulated expression of the BH3-only factor Bmf in mammary epithelial anoikis and morphogenesis.

Schmelzle T, Mailleux AA, Overholtzer M, Carroll JS, Solimini NL, Lightcap ES, Veiby OP, Brugge JS.

Proc Natl Acad Sci U S A. 2007 Mar 6;104(10):3787-92. Epub 2007 Feb 26.


Functional proteomics approach to investigate the biological activities of cDNAs implicated in breast cancer.

Witt AE, Hines LM, Collins NL, Hu Y, Gunawardane RN, Moreira D, Raphael J, Jepson D, Koundinya M, Rolfs A, Taron B, Isakoff SJ, Brugge JS, LaBaer J.

J Proteome Res. 2006 Mar;5(3):599-610.


Psoriasin (S100A7) and calgranulin-B (S100A9) induction is dependent on reactive oxygen species and is downregulated by Bcl-2 and antioxidants.

Carlsson H, Yhr M, Petersson S, Collins N, Polyak K, Enerb├Ąck C.

Cancer Biol Ther. 2005 Sep;4(9):998-1005. Epub 2005 Sep 23.


G1/S cell cycle arrest provides anoikis resistance through Erk-mediated Bim suppression.

Collins NL, Reginato MJ, Paulus JK, Sgroi DC, Labaer J, Brugge JS.

Mol Cell Biol. 2005 Jun;25(12):5282-91.


The role of apoptosis in creating and maintaining luminal space within normal and oncogene-expressing mammary acini.

Debnath J, Mills KR, Collins NL, Reginato MJ, Muthuswamy SK, Brugge JS.

Cell. 2002 Oct 4;111(1):29-40. Erratum in: Cell. 2002 Nov 27;111(5):757..


Modulation of paclitaxel resistance by annexin IV in human cancer cell lines.

Han EK, Tahir SK, Cherian SP, Collins N, Ng SC.

Br J Cancer. 2000 Jul;83(1):83-8.

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