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A Novel Tetramethylpyrazine Derivative Protects Against Glutamate-Induced Cytotoxicity Through PGC1α/Nrf2 and PI3K/Akt Signaling Pathways.

Chen H, Cao J, Zhu Z, Zhang G, Shan L, Yu P, Wang Y, Sun Y, Zhang Z.

Front Neurosci. 2018 Aug 15;12:567. doi: 10.3389/fnins.2018.00567. eCollection 2018.


Differentially expressed genes in response to amitraz treatment suggests a proposed model of resistance to amitraz in R. decoloratus ticks.

Baron S, Barrero RA, Black M, Bellgard MI, van Dalen EMS, Fourie J, Maritz-Olivier C.

Int J Parasitol Drugs Drug Resist. 2018 Jun 18;8(3):361-371. doi: 10.1016/j.ijpddr.2018.06.005. [Epub ahead of print]


MicroRNA-132 provides neuroprotection for tauopathies via multiple signaling pathways.

El Fatimy R, Li S, Chen Z, Mushannen T, Gongala S, Wei Z, Balu DT, Rabinovsky R, Cantlon A, Elkhal A, Selkoe DJ, Sonntag KC, Walsh DM, Krichevsky AM.

Acta Neuropathol. 2018 Oct;136(4):537-555. doi: 10.1007/s00401-018-1880-5. Epub 2018 Jul 7.


RNA Editing Deficiency in Neurodegeneration.

Lorenzini I, Moore S, Sattler R.

Adv Neurobiol. 2018;20:63-83. doi: 10.1007/978-3-319-89689-2_3.


Inflammatory Cytokine, IL-1β, Regulates Glial Glutamate Transporter via microRNA-181a in vitro.

Zumkehr J, Rodriguez-Ortiz CJ, Medeiros R, Kitazawa M.

J Alzheimers Dis. 2018;63(3):965-975. doi: 10.3233/JAD-170828.


The Parkinson's Disease-Linked Protein DJ-1 Associates with Cytoplasmic mRNP Granules During Stress and Neurodegeneration.

Repici M, Hassanjani M, Maddison DC, Garção P, Cimini S, Patel B, Szegö ÉM, Straatman KR, Lilley KS, Borsello T, Outeiro TF, Panman L, Giorgini F.

Mol Neurobiol. 2018 Apr 19. doi: 10.1007/s12035-018-1084-y. [Epub ahead of print]


In Vitro Assays for Mouse Müller Cell Phenotyping Through microRNA Profiling in the Damaged Retina.

Reyes-Aguirre LI, Quintero H, Estrada-Leyva B, Lamas M.

Methods Mol Biol. 2018;1753:305-315. doi: 10.1007/978-1-4939-7720-8_21.


Metabotropic glutamate receptor involvement in the pathophysiology of amyotrophic lateral sclerosis: new potential drug targets for therapeutic applications.

Battaglia G, Bruno V.

Curr Opin Pharmacol. 2018 Feb;38:65-71. doi: 10.1016/j.coph.2018.02.007. Epub 2018 Mar 9. Review.


Synaptic dysfunction and altered excitability in C9ORF72 ALS/FTD.

Starr A, Sattler R.

Brain Res. 2018 Aug 15;1693(Pt A):98-108. doi: 10.1016/j.brainres.2018.02.011. Epub 2018 Feb 14. Review.


Biomarkers of Amyotrophic Lateral Sclerosis: Current Status and Interest of Oxysterols and Phytosterols.

Vejux A, Namsi A, Nury T, Moreau T, Lizard G.

Front Mol Neurosci. 2018 Jan 31;11:12. doi: 10.3389/fnmol.2018.00012. eCollection 2018. Review.


A Regulatory Circuitry Between Gria2, miR-409, and miR-495 Is Affected by ALS FUS Mutation in ESC-Derived Motor Neurons.

Capauto D, Colantoni A, Lu L, Santini T, Peruzzi G, Biscarini S, Morlando M, Shneider NA, Caffarelli E, Laneve P, Bozzoni I.

Mol Neurobiol. 2018 Oct;55(10):7635-7651. doi: 10.1007/s12035-018-0884-4. Epub 2018 Feb 12.


Cross-talk between pathogenic mechanisms in neurodegeneration: the role of oxidative stress in Amyotrophic Lateral Sclerosis.

Chico L, Modena M, Lo Gerfo A, Ricci G, Caldarazzo Ienco E, Ryskalin L, Fornai F, Siciliano G.

Arch Ital Biol. 2017 Dec 1;155(4):131-141. doi: 10.12871/00039829201744. Review.


C9ORF72 repeat expansion causes vulnerability of motor neurons to Ca2+-permeable AMPA receptor-mediated excitotoxicity.

Selvaraj BT, Livesey MR, Zhao C, Gregory JM, James OT, Cleary EM, Chouhan AK, Gane AB, Perkins EM, Dando O, Lillico SG, Lee YB, Nishimura AL, Poreci U, Thankamony S, Pray M, Vasistha NA, Magnani D, Borooah S, Burr K, Story D, McCampbell A, Shaw CE, Kind PC, Aitman TJ, Whitelaw CBA, Wilmut I, Smith C, Miles GB, Hardingham GE, Wyllie DJA, Chandran S.

Nat Commun. 2018 Jan 24;9(1):347. doi: 10.1038/s41467-017-02729-0.


Tubby-like protein 1 (Tulp1) is a target of microRNA-134 and is down-regulated in experimental epilepsy.

Rodriguez AS, Engel T, Palfi A, Farrar GJ, Henshall DC, Jimenez-Mateos EM.

Int J Physiol Pathophysiol Pharmacol. 2017 Dec 25;9(6):178-187. eCollection 2017.


Causative Genes in Amyotrophic Lateral Sclerosis and Protein Degradation Pathways: a Link to Neurodegeneration.

Maurel C, Dangoumau A, Marouillat S, Brulard C, Chami A, Hergesheimer R, Corcia P, Blasco H, Andres CR, Vourc'h P.

Mol Neurobiol. 2018 Aug;55(8):6480-6499. doi: 10.1007/s12035-017-0856-0. Epub 2018 Jan 10. Review.


The Ubiquitin E3 Ligase TRAF6 Exacerbates Ischemic Stroke by Ubiquitinating and Activating Rac1.

Li T, Qin JJ, Yang X, Ji YX, Guo F, Cheng WL, Wu X, Gong FH, Hong Y, Zhu XY, Gong J, Wang Z, Huang Z, She ZG, Li H.

J Neurosci. 2017 Dec 13;37(50):12123-12140. doi: 10.1523/JNEUROSCI.1751-17.2017. Epub 2017 Nov 7.


Negative modulation of the GABAA ρ1 receptor function by l-cysteine.

Beltrán González AN, Vicentini F, Calvo DJ.

J Neurochem. 2018 Jan;144(1):50-57. doi: 10.1111/jnc.14237. Epub 2017 Nov 7.


Sonic hedgehog induces GLT-1 degradation via PKC delta to suppress its transporter activities.

Wang Y, Lu S, Qu Z, Wu L, Wang Y.

Neuroscience. 2017 Dec 4;365:217-225. doi: 10.1016/j.neuroscience.2017.09.051. Epub 2017 Oct 6.


Changes in the expression level of MAPK pathway components induced by monosodium glutamate-administration produce neuronal death in the hippocampus from neonatal rats.

Rivera-Carvantes MC, Jarero-Basulto JJ, Feria-Velasco AI, Beas-Zárate C, Navarro-Meza M, González-López MB, Gudiño-Cabrera G, García-Rodríguez JC.

Neuroscience. 2017 Dec 4;365:57-69. doi: 10.1016/j.neuroscience.2017.09.029. Epub 2017 Sep 24.


Massive transcriptome sequencing of human spinal cord tissues provides new insights into motor neuron degeneration in ALS.

D'Erchia AM, Gallo A, Manzari C, Raho S, Horner DS, Chiara M, Valletti A, Aiello I, Mastropasqua F, Ciaccia L, Locatelli F, Pisani F, Nicchia GP, Svelto M, Pesole G, Picardi E.

Sci Rep. 2017 Aug 30;7(1):10046. doi: 10.1038/s41598-017-10488-7.

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