Sort by
Items per page

Send to

Choose Destination

Search results

Items: 1 to 20 of 63


The Combination of IFN β and TNF Induces an Antiviral and Immunoregulatory Program via Non-Canonical Pathways Involving STAT2 and IRF9.

Mariani MK, Dasmeh P, Fortin A, Caron E, Kalamujic M, Harrison AN, Hotea DI, Kasumba DM, Cervantes-Ortiz SL, Mukawera E, Serohijos AWR, Grandvaux N.

Cells. 2019 Aug 17;8(8). pii: E919. doi: 10.3390/cells8080919.


CSV2018: The 2nd Symposium of the Canadian Society for Virology.

Grandvaux N, McCormick C.

Viruses. 2019 Jan 18;11(1). pii: E79. doi: 10.3390/v11010079.


Therapeutic Targeting of RIG-I and MDA5 Might Not Lead to the Same Rome.

Kasumba DM, Grandvaux N.

Trends Pharmacol Sci. 2019 Feb;40(2):116-127. doi: 10.1016/ Epub 2018 Dec 31. Review.


Interleukin (IL)-6 Inhibits IL-27- and IL-30-Mediated Inflammatory Responses in Human Monocytes.

Petes C, Mariani MK, Yang Y, Grandvaux N, Gee K.

Front Immunol. 2018 Feb 15;9:256. doi: 10.3389/fimmu.2018.00256. eCollection 2018.


Virus Infection Triggers MAVS Polymers of Distinct Molecular Weight.

Zamorano Cuervo N, Osseman Q, Grandvaux N.

Viruses. 2018 Jan 30;10(2). pii: E56. doi: 10.3390/v10020056.


Structural basis of STAT2 recognition by IRF9 reveals molecular insights into ISGF3 function.

Rengachari S, Groiss S, Devos JM, Caron E, Grandvaux N, Panne D.

Proc Natl Acad Sci U S A. 2018 Jan 23;115(4):E601-E609. doi: 10.1073/pnas.1718426115. Epub 2018 Jan 9.


DUSP1 regulates apoptosis and cell migration, but not the JIP1-protected cytokine response, during Respiratory Syncytial Virus and Sendai Virus infection.

Robitaille AC, Caron E, Zucchini N, Mukawera E, Adam D, Mariani MK, Gélinas A, Fortin A, Brochiero E, Grandvaux N.

Sci Rep. 2017 Dec 12;7(1):17388. doi: 10.1038/s41598-017-17689-0.


HIV-1 selectively targets gut-homing CCR6+CD4+ T cells via mTOR-dependent mechanisms.

Planas D, Zhang Y, Monteiro P, Goulet JP, Gosselin A, Grandvaux N, Hope TJ, Fassati A, Routy JP, Ancuta P.

JCI Insight. 2017 Aug 3;2(15). pii: 93230. doi: 10.1172/jci.insight.93230. eCollection 2017 Aug 3.


Detection of IKKε by immunohistochemistry in primary breast cancer: association with EGFR expression and absence of lymph node metastasis.

Williams V, Grosset AA, Zamorano Cuervo N, St-Pierre Y, Sylvestre MP, Gaboury L, Grandvaux N.

BMC Cancer. 2017 May 22;17(1):356. doi: 10.1186/s12885-017-3321-6.


1st Workshop of the Canadian Society for Virology.

McCormick C, Grandvaux N.

Viruses. 2017 Mar 20;9(3). pii: E54. doi: 10.3390/v9030054.


Respiratory Syncytial Virus and Cellular Stress Responses: Impact on Replication and Physiopathology.

Cervantes-Ortiz SL, Zamorano Cuervo N, Grandvaux N.

Viruses. 2016 May 12;8(5). pii: E124. doi: 10.3390/v8050124. Review.


A High Resolution Method to Monitor Phosphorylation-dependent Activation of IRF3.

Robitaille AC, Mariani MK, Fortin A, Grandvaux N.

J Vis Exp. 2016 Jan 24;(107):e53723. doi: 10.3791/53723.


Redox-modulating agents target NOX2-dependent IKKε oncogenic kinase expression and proliferation in human breast cancer cell lines.

Mukawera E, Chartier S, Williams V, Pagano PJ, Lapointe R, Grandvaux N.

Redox Biol. 2015 Dec;6:9-18. doi: 10.1016/j.redox.2015.06.010. Epub 2015 Jun 23.


Lung epithelial NOX/DUOX and respiratory virus infections.

Grandvaux N, Mariani M, Fink K.

Clin Sci (Lond). 2015 Mar;128(6):337-47. doi: 10.1042/CS20140321. Review.


Fludarabine downregulates indoleamine 2,3-dioxygenase in tumors via a proteasome-mediated degradation mechanism.

Hanafi LA, Gauchat D, Godin-Ethier J, Possamaï D, Duvignaud JB, Leclerc D, Grandvaux N, Lapointe R.

PLoS One. 2014 Jun 9;9(6):e99211. doi: 10.1371/journal.pone.0099211. eCollection 2014.


Sustained activation of interferon regulatory factor 3 during infection by paramyxoviruses requires MDA5.

Grandvaux N, Guan X, Yoboua F, Zucchini N, Fink K, Doyon P, Martin L, Servant MJ, Chartier S.

J Innate Immun. 2014;6(5):650-62. doi: 10.1159/000360764. Epub 2014 Apr 30.


STAT2 and IRF9: Beyond ISGF3.

Fink K, Grandvaux N.

JAKSTAT. 2013 Oct 1;2(4):e27521. doi: 10.4161/jkst.27521. Epub 2013 Dec 18. Review.


Pathogen recognition receptor crosstalk in respiratory syncytial virus sensing: a host and cell type perspective.

Marr N, Turvey SE, Grandvaux N.

Trends Microbiol. 2013 Nov;21(11):568-74. doi: 10.1016/j.tim.2013.08.006. Epub 2013 Oct 9.


Genome-wide RNAi screen reveals a new role of a WNT/CTNNB1 signaling pathway as negative regulator of virus-induced innate immune responses.

Baril M, Es-Saad S, Chatel-Chaix L, Fink K, Pham T, Raymond VA, Audette K, Guenier AS, Duchaine J, Servant M, Bilodeau M, Cohen E, Grandvaux N, Lamarre D.

PLoS Pathog. 2013;9(6):e1003416. doi: 10.1371/journal.ppat.1003416. Epub 2013 Jun 13.


IFNβ/TNFα synergism induces a non-canonical STAT2/IRF9-dependent pathway triggering a novel DUOX2 NADPH oxidase-mediated airway antiviral response.

Fink K, Martin L, Mukawera E, Chartier S, De Deken X, Brochiero E, Miot F, Grandvaux N.

Cell Res. 2013 May;23(5):673-90. doi: 10.1038/cr.2013.47. Epub 2013 Apr 2. Erratum in: Cell Res. 2014 Apr;24(4):509.

Supplemental Content

Loading ...
Support Center