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Cell Host Microbe. 2012 Dec 13;12(6):737-8. doi: 10.1016/j.chom.2012.11.006.

YopM puts caspase-1 on ice.

Author information

1
Department of Microbiology and Immunology and Lineberger Comprehensive Cancer Center, University of North Carolina at Chapel Hill, Chapel Hill, NC 27599, USA.

Abstract

Caspase-1-mediated detection of pathogens is a potent arm of the innate immune system. LaRock and Cookson (2012) show that the Yersinia type III secretion effector, YopM, directly inhibits caspase-1.

PMID:
23245318
PMCID:
PMC3590850
DOI:
10.1016/j.chom.2012.11.006
[Indexed for MEDLINE]
Free PMC Article

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