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Appl Environ Microbiol. 2010 Oct;76(20):6955-61. doi: 10.1128/AEM.01393-10. Epub 2010 Aug 27.

Acquisition of iron by alkaliphilic bacillus species.

Author information

1
Department of Microbiology and Immunology, University of Otago, Dunedin, New Zealand.

Abstract

The biochemical and molecular mechanisms used by alkaliphilic bacteria to acquire iron are unknown. We demonstrate that alkaliphilic (pH > 9) Bacillus species are sensitive to artificial iron (Fe³+) chelators and produce iron-chelating molecules. These alkaliphilic siderophores contain catechol and hydroxamate moieties, and their synthesis is stimulated by manganese(II) salts and suppressed by FeCl₃ addition. Purification and mass spectrometric characterization of the siderophore produced by Caldalkalibacillus thermarum failed to identify any matches to previously observed fragmentation spectra of known siderophores, suggesting a novel structure.

PMID:
20802068
PMCID:
PMC2953014
DOI:
10.1128/AEM.01393-10
[Indexed for MEDLINE]
Free PMC Article

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